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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
CellProfiler Image Analysis Software
 
Resource Report
Resource Website
1000+ mentions
CellProfiler Image Analysis Software (RRID:SCR_007358) software resource, image analysis software, data processing software, software application Software tool to enable biologists without training in computer vision or programming to quantitatively measure phenotypes from thousands of images automatically. It counts cells and also measures the size, shape, intensity and texture of every cell (and every labeled subcellular compartment) in every image. It was designed for high throughput screening but can perform automated image analysis for images from time-lapse movies and low-throughput experiments. CellProfiler has an increasing number of algorithms to identify and measure properties of neuronal cell types. high-throughput, high content imaging, software, image, cell, phenotype, measurement, subcellular, intensity, size, shape, analysis, algorithm is listed by: Debian
is related to: CellProfiler Analyst
has parent organization: Broad Institute
NIGMS R01 GM089652;
NIGMS RC2 GM092519;
NHGRI RL1 HG004671
PMID:21349861
PMID:17076895
PMID:19014601
PMID:19188593
Free, Available for download, Freely available SCR_010649, nlx_66812, nif-0000-00280 https://sources.debian.org/src/cellprofiler/ SCR_007358 Cell Profiler, CellProfiler - cell image analysis software 2026-02-14 02:05:31 3265
Protein Cross-Linking Database
 
Resource Report
Resource Website
1+ mentions
Protein Cross-Linking Database (RRID:SCR_021027) ProXL, proxl, Protein XL web service, data or information resource, data access protocol, software resource, database Web application and database designed for sharing, visualizing, and analyzing protein cross-linking mass spectrometry data with emphasis on structural analysis and quality control. Includes public and private data sharing capabilities, project based interface designed to ensure security and facilitate collaboration among multiple researchers. Used for private collaboration and public data dissemination. Protein cross-linking, mass spectrometry data, analysis, visualization, sharing, structural analysis, quality control, private collaboration, public data dissemination uses: Kojak
has parent organization: University of Washington; Seattle; USA
NIGMS P41 GM103533;
University of Washington Proteomics Resource
PMID:27302480 Free, Available for download, Freely available https://github.com/yeastrc/proxl-web-app SCR_021027 Protein XL Database 2026-02-14 02:04:41 5
Kojak
 
Resource Report
Resource Website
1+ mentions
Kojak (RRID:SCR_021028) data analysis software, software resource, data processing software, software application Software tool for identification of cross-linked peptides from mass spectra. Used for analysis of chemically cross-linked protein complexes. Used to analyze both novel and existing data sets. Mass spectra, cross-linked peptides identification, protein complexes analysis, novel data analysis, existing data analysis is used by: Protein Cross-Linking Database
has parent organization: University of Washington; Seattle; USA
National Science Foundation MRI grant 0923536;
NIGMS P50 GM076547;
NIGMS P50 GM08722150;
NCRR S10 RR027584;
NIGMS P41 GM103533
PMID:25812159 Free, Available for download, Freely available SCR_021028 2026-02-14 02:04:09 3
Simbios
 
Resource Report
Resource Website
1+ mentions
Simbios (RRID:SCR_004320) postdoctoral program resource, training resource, portal, journal article, data or information resource, organization portal, software resource Simbios is the NIH Center for physics-based Simulation of Biological Structures. Simbios provides infrastructure, software, and training to help biomedical researchers understand biological form and function as they create novel drugs, synthetic tissues, medical devices, and surgical interventions. Simbios is investigating a wide scale of biological structures - from molecules to organisms. Driving biological problems include RNA folding, protein folding, myosin dynamics, cardiovascular dynamics, and neuromuscular biomechanics. Investigators interested in collaborating with Simbios can apply for NIH funding. To encourage collaboration in building accurate biological models and simulations, Simbios also provides the biomedical community with https://simtk.org, a free, secure, distributed, development system for projects. Projects may include models, software, data, documentation, publications, and graphics and have automatic backups and off-site storage. Projects may be public or private and have project-specific mailing lists, forums, bug & feature databases, news, blogs, and source-code repositories. Simbios is developing and disseminating the SimTK core simulation toolkit, (simtk.org/home/simtkcore). SimTK core is open-source software developed by experienced professionals. The software includes advanced capabilities for modeling the geometry and physics of biological systems. To ensure utility and accuracy, the software and training material is being developed and tested in close collaboration with biomedical scientists. Simbios has developed OpenSim, an application for advanced neuromuscular modeling that uses the SimTK toolkit, and is making it openly available at simtk.org/home/opensim. Simbios also publishes the Biomedical Computation Review, a magazine devoted to the science and tools in biocomputation, aimed at the community which encompasses the diverse biocomputation disciplines. To help researchers find high quality software and tools Simbios has also establishes the Simbiome an inventory of high-quality commercial and academic bio-simulation tools. Simbios has recurring openings for postdoctoral researchers. is related to: Biomedical Computation Review
is related to: National Centers for Biomedical Computing
has parent organization: Stanford University; Stanford; California
is parent organization of: Simtk.org
is parent organization of: Biomedical Computation Review
is parent organization of: BioSimulation Course
NIGMS U54 GM072970 PMID:22081222
PMID:20107615
nlx_33018 SCR_004320 Simbios - NIH Center for Biomedical Computation at Stanford, physics-based Simulation of Biological Structures 2026-02-14 02:04:52 1
MOPED - Model Organism Protein Expression Database
 
Resource Report
Resource Website
1+ mentions
MOPED - Model Organism Protein Expression Database (RRID:SCR_006065) MOPED data analysis service, analysis service resource, resource, data or information resource, production service resource, service resource, database An expanding multi-omics resource that enables rapid browsing of gene and protein expression information from publicly available studies on humans and model organisms. MOPED also serves the greater research community by enabling users to visualize their own expression data, compare it with existing studies, and share it with others via private accounts. MOPED uniquely provides gene and protein level expression data, meta-analysis capabilities and quantitative data from standardized analysis utilizing SPIRE (Systematic Protein Investigative Research Environment). Data can be queried for specific genes and proteins; browsed based on organism, tissue, localization and condition; and sorted by false discovery rate and expression. MOPED links to various gene, protein, and pathway databases, including GeneCards, Entrez, UniProt, KEGG and Reactome. The current version of MOPED (MOPED 2.5) The current version of MOPED (MOPED 2.5, 2014) contains approximately 5 million total records including ~260 experiments and ~390 conditions. protein expression, gene expression, model organism, gene, protein, pathway, proteomics, transcriptomics, data visualization, overlap plot, heatmap, dot plot, data sharing, protein localization, gene localization is related to: GeneCards
is related to: UniProt
is related to: KEGG
is related to: Reactome
Robert B McMillen Foundation ;
NSF DBI0544757;
NIGMS 5R01GM076680;
NIDDK UO1DK072473;
NIDDK 1U01DK089571
PMID:24350770
PMID:22139914
nlx_151470 SCR_006065 Multi-Omics Profiling Expression Database 2026-02-14 02:04:53 2
EcoliWiki
 
Resource Report
Resource Website
1+ mentions
EcoliWiki (RRID:SCR_010656) EcoliWiki web service, data or information resource, wiki, data access protocol, software resource, narrative resource A component of EcoliHub, EcoliWiki is a wiki-based system for finding, editing, and adding information about E. coli K-12 and other model organism strains of E. coli. EcoliWiki is being constructed to include information about bacteriophage, plasmids, and mobile genetic elements. Information should be easily accessible and correct, and users have the right to edit any information they feel is incorrect. Most of the E. coli information was initially seeded with a subset of information from parsing EcoCyc data dumps. For phage gamma and the F plasmid, Genbank accessions were converted to GFF, which was parsed into the appropriate tables. Other sources of content include: * user additions * monthly addition of annotations from EcoCyc * structural data from the PDB * domains and motif information from InterPro * various databases including EcoGene, RegulonDB, Genbank, GenoBase, ASAP * many many scientific papers EcoliWiki participates in the RefGenome project. EcoliWiki provides REST web services as part of the EcoliHub Web Services infrastructure project. phantom gene, genome sequence, bacteriophage, escherichia coli, e. coli, prokaryotic, gene, model organism, annotation NIGMS U24GM088849 nlx_68806 SCR_010656 2026-02-14 02:04:34 4
BioDepot-workflow-builder
 
Resource Report
Resource Website
1+ mentions
BioDepot-workflow-builder (RRID:SCR_017402) Bwb software resource, workflow software, data processing software, software application Software tool to create and execute reproducible bioinformatics workflows using drag and drop interface. Graphical widgets represent Docker containers executing modular task. Widgets are linked graphically to build bioinformatics workflows that can be reproducibly deployed across different local and cloud platforms. Each widget contains form-based user interface to facilitate parameter entry and console to display intermediate results. bioinformatics, big, data, workflow, reproducible, Docker NIGMS R01 GM126019;
NHLBI U54 HL127624;
NHGRI U24HG012674;
NIAID R03AI159286
DOI:10.1016/j.cels.2019.08.007 Free, Available for download, Freely available SCR_017402 2026-02-14 02:04:57 1
StringTie
 
Resource Report
Resource Website
1000+ mentions
StringTie (RRID:SCR_016323) sequence analysis software, data processing software, data analysis software, software application, software resource Software application for assembling of RNA-Seq alignments into potential transcripts. It enables improved reconstruction of a transcriptome from RNA-seq reads. This transcript assembling and quantification program is implemented in C++ . assembling, RNA, sequence, transcript, gene, alignment, reconstruction, read, analysis, process, bio.tools is listed by: bio.tools
is listed by: Debian
is listed by: OMICtools
the Cancer Prevention and Research Institute of Texas ;
NHGRI R01 HG006677;
NIGMS R01 GM105705;
NHGRI R01 HG006102;
NCI R01 CA120185;
NCI R01 CA134292
PMID:25690850
DOI:10.1038/nbt.3122
Open source, Free, Freely available, Available for download biotools:stringtie, OMICS_07226 https://github.com/gpertea/stringtie
https://bio.tools/stringtie
https://sources.debian.org/src/stringtie/
SCR_016323 2026-02-14 02:04:34 4072
Oufti
 
Resource Report
Resource Website
10+ mentions
Oufti (RRID:SCR_016244) software resource, image analysis software, data processing software, software application Software designed for analysis of microscopy data. It performs sub-pixel precision detection, quantification of cells and fluorescence signals, as well as other image analysis functions. microscopy, data, imaging, image, analysis, pixel, fluorescent, bio.tools is listed by: Debian
is listed by: bio.tools
NIGMS R01 GM065835 PMID:26538279 biotools:oufti https://bio.tools/oufti SCR_016244 outfi 2026-02-14 02:05:34 13
RSRef
 
Resource Report
Resource Website
1+ mentions
RSRef (RRID:SCR_017211) software resource, data processing software, software application Software for fitting of atomic models into density maps derived from x-ray crystallography or electron microscopy. Fitting, atomic, model, density, map, x ray, crystallography, electron, microscopy NIGMS R01 GM66875;
NIGMS R01 GM78538
PMID:23376441 Free, Available for download, Freely available http://xtal.ohsu.edu/software/rsref/readme.txt SCR_017211 2026-02-14 02:05:38 1
Phenix.refine
 
Resource Report
Resource Website
10+ mentions
Phenix.refine (RRID:SCR_016736) Phenix.refine software resource, data processing software, software application Software tool for a general purpose crystallographic structure refinement within the PHENIX package. Serves as a critical component in automated model building, final structure refinement, structure validation and deposition to the wwPDB. crystallographic, structure, refinement, Phenix, model, building, validation is listed by: SoftCite
is provided by: Phenix
NIGMS GM063210;
US Department of Energy
PMID:22505256 Free, Available for download for non profit, For profit access PHENIX through a Consortium agreement, Tutorial available, Acknowledgement requested SCR_016736 Python-based Hierarchical ENvironment for Integrated Xtallography.refine, Phenix.refine, Phenix 2026-02-14 02:05:40 39
ProteomeTools
 
Resource Report
Resource Website
10+ mentions
ProteomeTools (RRID:SCR_018535) data or information resource, portal, project portal Project for building molecular and digital tools from human proteome to facilitate biomedical research, drug discovery, personalized medicine and life science research. Molecular tool, human proteome, proteome, human, peptide, data is related to: ProteomicsDB
is related to: ProteomeXchange
German Federal Ministry of Education and Research ;
Alexander von Humboldt Foundation ;
American Recovery and Reinvestment Act ;
NHGRI RC2 HG005805;
NIGMS R01 GM087221;
NCRR S10 RR027584;
NIGMS P50 GM076547;
European Research Council ;
Swiss National Science Foundation
PMID:28135259 Free, Freely available http://www.proteometools.org SCR_018535 2026-02-14 02:05:41 21
mosdepth
 
Resource Report
Resource Website
10+ mentions
mosdepth (RRID:SCR_018929) software resource, data processing software, software application Software command line tool for rapidly calculating genome wide sequencing coverage. Measures depth from BAM or CRAM files at either each nucleotide position in genome or for sets of genomic regions. Used for fast BAM/CRAM depth calculation for WGS, exome, or targeted sequencing quick coverage calculation for genomes and exomes. Calculating genome, wide sequencing coverage, depth measurement, BAM file, CRAM file, nucleotide position, genome, genomic region set, WGS exom, targeted sequencing, coverage calculation, exom, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
NHGRI R01 HG006693;
NHGRI R01 HG009141;
NIGMS R01 GM124355;
NCI U24 CA209999
PMID:29096012 Free, Available for download, Freely available OMICS_20873, biotools:mosdepth https://bio.tools/mosdepth
https://sources.debian.org/src/mosdepth/
SCR_018929 2026-02-14 02:05:18 38
CRISPResso
 
Resource Report
Resource Website
10+ mentions
CRISPResso (RRID:SCR_021538) sequence analysis software, data processing software, data analysis software, software toolkit, software application, software resource Software suite of tools to qualitatively and quantitatively evaluate outcomes of genome editing experiments in which target loci are subject to deep sequencing and provides integrated, user friendly interface. Used for analysis of CRISPR-Cas9 genome editing outcomes from sequencing data. CRISPResso2 provides accurate and rapid genome editing sequence analysis.Used for analysis of deep sequencing data for rapid and intuitive interpretation of genome editing experiments. Quantification, visualization, CRISPR-Cas9 outcomes, coding sequences evaluation, noncoding elements evaluation, selected off target sites evaluation, genome editing evaluation. NHGRI RM1 HG009490;
NIBIB R01 EB022376;
NIGMS R35 GM118062;
NIGMS R35 GM118158;
NIDDK R03 DK109232;
NHLBI P01 HL32262;
NHGRI R00 HG008399;
NIDDK P30 DK049216;
NHLBI R01 HL119099;
NHGRI R01 HG005085
PMID:27404874
PMID:30809026
Free, Available for download, Freely available https://github.com/pinellolab/CRISPResso2
https://github.com/pinellolab/CRISPResso
SCR_021538 CRISPResso2 2026-02-14 02:04:17 21
RepEnrich
 
Resource Report
Resource Website
10+ mentions
RepEnrich (RRID:SCR_021733) data analysis software, software resource, data processing software, software application Software tool to profile enrichment of next generation sequencing reads at transposable elements. Method to estimate repetitive element enrichment using high throughput sequencing data. Used to study genome wide transcriptional regulation of repetitive elements.RepEnrich2 is updated method to estimate repetitive element enrichment using high-throughput sequencing data. profile enrichment, next generation sequencing reads, transposable elements, estimate repetitive element enrichment, genome wide transcriptional regulation, sequencing data has parent organization: Brown University; Rhode Island; USA NIA K25 AG028753;
NIGMS T32 GM007601;
NIA R37 AG016694
PMID:25012247 Free, Available for download, Freely available https://github.com/nerettilab/RepEnrich2 SCR_021733 RepEnrich2 2026-02-14 02:04:22 21
DeepCell
 
Resource Report
Resource Website
10+ mentions
DeepCell (RRID:SCR_022197) data processing software, software application, segmentation software, software resource, image analysis software Software for segmenting individual cells in microscopy images using deep learning. Cell segmentation software. segmenting individual cells, microscopy image, cell segmentation Paul Allen Family Foundation ;
NIGMS F32 GM119319;
NIGMS P50 GM107615;
NLM DP1 LM01150
DOI:10.1371/journal.pcbi.1005177 Free, Available for download, Freely available SCR_022197 Deepcell 2026-02-14 02:04:27 10
SCIRun
 
Resource Report
Resource Website
10+ mentions
SCIRun (RRID:SCR_002541) SCIRun data visualization software, data processing software, software toolkit, software application, software resource, simulation software A Problem Solving Environment (PSE) for modeling, simulation and visualization of scientific problems. SCIRun now includes the biomedical components formally released as BioPSE, as well as BioMesh3D. BioMesh3D is a free, easy to use program for generating quality meshes for the use in biological simulations. The most recent stable release is version 4.6. modeling, simulation, visualization is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is related to: BioMesh3D
is related to: BioMesh3D
is related to: BioPSE
is related to: BioPSE
has parent organization: University of Utah; Utah; USA
NCRR 5P41RR012553-15;
NIGMS 8 P41 GM103545-15
Free, Available for download, Freely available nlx_155949 http://www.nitrc.org/projects/scirun SCR_002541 2026-02-14 02:04:51 21
ImageJ
 
Resource Report
Resource Website
10000+ mentions
ImageJ (RRID:SCR_003070) data processing software, software toolkit, software application, image processing software, software resource, image analysis software Open source Java based image processing software program designed for scientific multidimensional images. ImageJ has been transformed to ImageJ2 application to improve data engine to be sufficient to analyze modern datasets. image, data, processing, analysis, datasets, visualization, uses: NeuriteTracer
is used by: Mouse Behavioral Analysis Toolbox
is used by: Focinator
is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is listed by: Debian
is listed by: SoftCite
is related to: uManager
is related to: Fiji
is related to: NIH Image
is related to: TrakEM2
is related to: BioVoxxel Toolbox
is related to: Golddigger
is related to: Analyze Complex Roots Tool
is related to: Analyze Spheroid Cell Invasion In 3D Matrix
is related to: PyImageJ
has parent organization: Research Services Branch National Institutes of Mental Health
has plug in: Diffusing Tensor Imaging in Java
has plug in: OrientationJ
has plug in: GRatio for ImageJ
has plug in: BioVoxxel Toolbox
has plug in: WormSizer
has plug in: MultiStackReg
has plug in: Iterative Deconvolve 3D
has plug in: Thunder STORM
has plug in: Whisker tracking macro
has plug in: 3D Roi Manager
has plug in: 3D Objects Counter
has plug in: BoneJ
has plug in: QuickFigures
has plug in: ObjectJ
has plug in: ADAPT
has plug in: DHM Utilities
has plug in: Sholl Analysis
has plug in: nTracer
has plug in: IHC Profiler
has plug in: MicrobeJ
has plug in: AccPbFRET
has plug in: RiFRET
has plug in: JaCoP
has plug in: Cell Counter Plugin for ImageJ
has plug in: Puncta Analyzer
has plug in: SpinalJ
works with: Intensity Ratio Nuclei Cytoplasm Tool
works with: 3D ImageJ Suite
works with: Wound Healing Tool
works with: MorphoLibJ
NINDS ;
NIGMS RC2 GM092519;
Wellcome Trust Strategic Award 095931;
the Laboratory for Optical and Computational Instrumentation ;
the Morgridge Institute for Research ;
NIH ;
NIMH
PMID:22930834
PMID:29187165
DOI:10.1038/nmeth.2089
Free, Available for download, Freely available ascl:1206.013, rid_000070, Q1659584, 2012ascl.soft06013R, nif-0000-30467, SCR_018407 https://imagej.net/ij/
http://rsbweb.nih.gov/ij
https://imagej.nih.gov/ij/download.html
https://imagej.nih.gov/ij/
https://sources.debian.org/src/imagej/
https://imagej.nih.gov/ij/, http://www.nitrc.org/projects/incf_imagej, SCR_003070 Image J, ImageJ - Image Processing and Analysis in Java, ImageJ2, ImageJ 2026-02-14 02:04:29 27070
ToRNADo
 
Resource Report
Resource Website
50+ mentions
ToRNADo (RRID:SCR_002706) data visualization software, software resource, data processing software, software application A software application for animating and visualising RNA and other macromolecular structures. Users are able to use their intuition to interactively refold RNA structures and produce morphs from one structure to another. It allow researchers to explore and manipulate molecular structures Imported from BiositeMaps registry, to better understand structure:function relationships, folding pathways, and molecular motion. duplex, protein, rna, visualization has parent organization: Stanford University; Stanford; California NIH ;
NIGMS R01GM107340;
NIGMS U54GM072970
Free, Available for download, Freely available nif-0000-23335 SCR_002706 2026-02-14 02:04:29 95
Add Health (National Longitudinal Study of Adolescent Health)
 
Resource Report
Resource Website
10+ mentions
Add Health (National Longitudinal Study of Adolescent Health) (RRID:SCR_007434) Add Health data or information resource, database Longitudinal study of a nationally representative sample of adolescents in grades 7-12 in the United States during the 1994-95 school year. Public data on about 21,000 people first surveyed in 1994 are available on the first phases of the study, as well as study design specifications. It also includes some parent and biomarker data. The Add Health cohort has been followed into young adulthood with four in-home interviews, the most recent in 2008, when the sample was aged 24-32. Add Health combines longitudinal survey data on respondents social, economic, psychological and physical well-being with contextual data on the family, neighborhood, community, school, friendships, peer groups, and romantic relationships, providing unique opportunities to study how social environments and behaviors in adolescence are linked to health and achievement outcomes in young adulthood. The fourth wave of interviews expanded the collection of biological data in Add Health to understand the social, behavioral, and biological linkages in health trajectories as the Add Health cohort ages through adulthood. The restricted-use contract includes four hours of free consultation with appropriate staff; after that, there''s a fee for help. Researchers can also share information through a listserv devoted to the database. adolescent, longitudinal, adult human, interview, social, behavior, health, early adult human, FASEB list has parent organization: University of North Carolina at Chapel Hill; North Carolina; USA Aging NICHD ;
NCI ;
CDC ;
NIAID ;
NIMHD ;
NIDCD ;
NIGMS ;
NIMH ;
NINR ;
NIA ;
NIAAA ;
NIDA ;
NSF ;
NIH ;
Department of Health and Human Services ;
MacArthur Foundation ;
Robert Wood Johnson Foundation
Restricted use nif-0000-00621 SCR_007434 National Longitudinal Study of Adolescent Health 2026-02-14 02:06:03 37

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