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https://www.cincinnatichildrens.org/research/cores/mmac

Provides solutions in areas of study design, bioinformatic processing of amplicon and shotgun metagenomic sequencing data, integration of metagenomic and clinical data structures, and statistical analyses of microbial community samples. MMAC works closely with Microbial Genomics and Metagenomics Laboratory to streamline workflows for metagenomic sequencing, bioinformatic processing, and statistical analysis of microbiome projects.

Proper citation: Cincinnati Children's Hospital Microbial Metagenomics Analysis Center Microbial Genomics and Metagenomics Core Facility (RRID:SCR_022649) Copy   

•   Source: SciCrunch Registry

https://research.med.psu.edu/core-facilities/light-microscopy/

Provides consultation and training in ultra high resolution imaging of cells and tissues in fixed or live states. Provides expertise in quantitative image analysis and consultations on microscopy related research projects.

Proper citation: Penn State Hershey College of Medicine Light Microscopy Imaging Core Facility (RRID:SCR_022526) Copy   

•   Source: SciCrunch Registry

https://www.utsouthwestern.edu/education/medical-school/departments/neurology/research/neuro-models-facility/

Facilitates scientific research of nervous system function to enhance development and testing of novel therapeutic strategies for treatment of nervous system disorders. Provides resource capacity typically unavailable or impractical in individual laboratory. Major areas of specialization include surgical approaches to model production and assessment, behavior testing of sensorimotor functions, in vivo electrophysiological recording (EEG, EMG, ERP). Procedures are intended for mice and rats. Procedures can be developed based on client interests.

Proper citation: University of Texas Southwestern Medical Center Neuro Models Core Facility (RRID:SCR_022529) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/CMSDLD/the-molecular-pathology-and-imaging-core-mpic.html

Provides histological services, equipment, and technical expertise for processing and analyses of digestive, pancreatic, and liver tissues as well as three dimensional tissue culture models.�Part of the Center for Molecular Studies in Digestive and Liver Diseases

Proper citation: University of Pennsylvania Perelman School of Medicine Molecular Pathology and Imaging Core (MPIC) (RRID:SCR_022420) Copy   

•   Source: SciCrunch Registry

https://bauercore.fas.harvard.edu/

Helps to advance research efforts in life sciences that cannot readily be accomplished in the traditional academic laboratory because of need for expensive instrumentation or automation, scientific or organizational infrastructure, or multidisciplinary expertise. Provides expertise and hands-on training and use of instrumentation for nominal fee. Researchers can sign up to use instrumentation through on-line scheduling system and conduct their experiments independently.

Proper citation: Harvard University Bauer Core Facility (RRID:SCR_022656) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/cvi/mouse-cardiovascular-phenotyping-core.html

Core provides services to assess cardiovascular function in mouse models and to provide validated surgical models of heart and vascular disease in mice to assess genetic or therapeutic interventions. Works with investigators to design and implement study along with any associated grant applications, animal protocol submissions and manuscript preparation. While central focus of facility is cardiovascular research, techniques employed are often useful to investigators in other fields. Helps to assess your needs and provide necessary technical training and scientific assistance in animal protocol preparation. Core runs on a fee for service model.�Accordingly, investigators will be responsible for costs incurred for their projects and prior animal protocol approval by Penn IACUC., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.

Proper citation: University of Pennsylvania Perelman School of Medicine Mouse Cardiovascular Phenotyping Core Facility (RRID:SCR_022419) Copy   

•   Source: SciCrunch Registry

https://www.cincinnatichildrens.org/research/cores/dna-sequencing-genotyping

Supports production and analysis of DNA and RNA related data. Provides DNA and RNA sequencing, Next Generation sequencing, DNA extraction and high and low throughput SNP genotyping.

Proper citation: Cincinnati Children's Hospital DNA Sequencing and Genotyping Core Facility (RRID:SCR_022630) Copy   

•   Source: SciCrunch Registry

https://www.cincinnatichildrens.org/research/cores/translational-core-laboratory/cell-manipulations-laboratory

Supports development, scale -up and processing of innovative cell based therapies for clinical studies.

Proper citation: Cincinnati Children's Hospital Cell Manipulation Laboratory Core Facility (RRID:SCR_022627) Copy   

•   Source: SciCrunch Registry

https://www.cincinnatichildrens.org/research/cores/dmac

Centralized resource for clinical research data management, programming for clinical research databases, and statistical analysis.

Proper citation: Cincinnati Children's Hospital Data Management and Analysis Center Core Facility (RRID:SCR_022625) Copy   

•   Source: SciCrunch Registry

https://www.cincinnatichildrens.org/research/cores/mouse-core

Offers services for researchers exploring cancer systems through animal models. Provides animals from specific inbred mouse strains primarily used in cancer and hematopoietic research, offers cell transplant, harvest and irradiation services and can handle animal cancer model systems involving xenotransplant procedures.

Proper citation: Cincinnati Children's Hospital Comprehensive Mouse and Cancer Core Facility (RRID:SCR_022624) Copy   

•   Source: SciCrunch Registry

https://www.cincinnatichildrens.org/research/cores/translational-core-laboratory/cell-processing-core

Supplies mononuclear cells, stem cells or other enriched cell populations. Provides stem cells and other tissue samples from normal donor or patient populations such as disease specific repositories or specific research studies requiring sample processing. Samples are provided fresh or cryopreserved according to availability, unprocessed or with further lab processing.Common processing techniques include PBMC isolation,Serum and plasma isolation,Separation of marker specific populations,Flow cytometric characterization of samples,Interferon gamma EliSpot.Additional services may be available upon request

Proper citation: Cincinnati Children's Hospital Cell Processing Core Facility (RRID:SCR_022623) Copy   

•   Source: SciCrunch Registry

https://www.unmc.edu/vcr/cores/vcr-cores/camri/index.html

Provides research MRI capabilities for investigators at UNMC and across greater Omaha area. Housed in Hixson-Lied Center, CAMRI operates Siemens 3T Prisma MRI instrument that can collect high quality data of any MR modality using advanced gradients and research grade pulse sequences. Variety of head coils (20-, 32-, and 64-channel) are available to optimize data collection for needs of specific studies. Studies incorporating functional MRI can take advantage of CAMRI�s suite of MRI-compatible response devices, mirrored 32-inch LCD screen, and integrated stimulus display computer.

Proper citation: University of Nebraska Medical Center Advanced Magnetic Resonance Imaging Core Facility (RRID:SCR_022468) Copy   

•   Source: SciCrunch Registry

https://www.unmc.edu/vcr/cores/vcr-cores/confocal-microscopy/index.html

Facility houses imaging technologies ranging from super resolution (~ 0.120 um to 0.020 um) to microscopic (~ 0.300 um) to mesoscopic (~ 1 um) biomedical imaging. Imaging specialists provide training and/or actively assist researchers collecting images across imaging instrumentation. Instrumentation includes Zeiss ELYRA PS.1 is inverted microscope for super resolution (SR) structured illumination microscopy (SIM) and single molecule localization microscopy (SMLM) including, PhotoActivated Localization Microscopy (PALM) using photo switchable/convertible fluorescent proteins, Total Internal Reflection Fluorescence (TIRF) and STochastic Optical Reconstruction Microscopy (STORM);Zeiss 800 CLSM with Airyscan is an inverted microscope dramatically increasing conventional confocal image resolution to ~180 nm using Airyscan technology; Zeiss 710 LSM is inverted microscope supporting most basic imaging applications, multi channel and spectral, co localization, live cell, 3D, and time series imaging; Zeiss Celldiscoverer 7 is widefield imaging system for automated, time lapse imaging of live samples; Zeiss Axioscan 7 is high performance whole slide scanning system for fluorescence, brightfield, and polarization imaging;Miltenyi Biotec Ultramicroscope II Light Sheet fluorescence microscope (LSFM) extends fluorescent imaging into true 3D, large scale volumetric imaging of intact tissues, organs, and small organisms. AMCF also houses several high-end data analysis workstations with premier image analysis software including HALO (Indica Labs) and IMARIS (Oxford Instruments) facilitating data rendering, analyses, and presentation options.

Proper citation: University of Nebraska Medical Center Advanced Microscopy Core Facility (RRID:SCR_022467) Copy   

•   Source: SciCrunch Registry

https://www.cincinnatichildrens.org/research/cores/animal

Offers behavioral phenotyping of rodent models as well as characterizing nervous system function in mouse and rat models through behavioral assays.

Proper citation: Cincinnati Children's Hospital Animal Behavior Core Facility (RRID:SCR_022621) Copy   

•   Source: SciCrunch Registry

http://www.ohri.ca/bioinformatics

Core of University of Ottawa and Ottawa Hospital Research Institute. Provides advice on bioinformatics research design, conduct bioinformatics analysis, and provide support for grant proposals that involve bioinformatics (including conducting pilot studies, support/collaboration letters and methodological text). Areas of expertise include:Analysis of high throughput sequencing data; single cell (Chromium 10x), RNA-seq (including small RNA), ChIP-seq, ATAC-seq, Hi-C.Large scale analysis integrating multiple data types.Helps to arrange for analysis of your biological samples with local core facilities such as StemCore, Proteomics Resource Center, or OHRI Mass Spectrometry Core Facility. Provides yearly training courses in RNA-seq analysis and Bioinformatics analysis using R as well as individual training and analysis support on request.

Proper citation: University of Ottawa Bioinformatics Core Facility (RRID:SCR_022466) Copy   

•   Source: SciCrunch Registry

https://www.cincinnatichildrens.org/research/divisions/d/dhc/cores/integrative-morphology/confocal-imaging

Provides Cincinnati Children s Hospital Medical Center; Cincinnati; Ohio resources in confocal, wide-field, and spatial technique applications.

Proper citation: Cincinnati Children's Hospital Confocal Imaging Core Facility (RRID:SCR_022628) Copy   

•   Source: SciCrunch Registry

http://bioinf.itmat.upenn.edu/

Provides project based bioinformatics support for ITMAT translational researchers. Provides computational infrastructure and programming support needed to conduct high-throughput proteomics experiments. We also support other genomics high-throughput technologies to a lesser extent. The projects range from building Web applications for data analysis pipelines, scripting, clinical and basic science research support, and database and algorithm development. Recent efforts have focused on explorations of new models of computation, specifically cloud computing and GPUs, for use in genomic scale research.

Proper citation: University of Pennsylvania Perelman School of Medicine ITMAT Bioinformatics Laboratory Core Facility (RRID:SCR_022486) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/CMSDLD/biomedical-data-science-core-bdsc.html

Core provides consultations and fee for service support in big data analyses using methods of data science in biomedical and health research related to digestive disease and liver research.

Proper citation: University of Pennsylvania Perelman School of Medicine Biomedical Data Science Core Facility (RRID:SCR_022485) Copy   

•   Source: SciCrunch Registry

https://somf.engr.tamu.edu/

Facility is focused on characterization of multifunctional soft materials. Includes four instrumentation suites based on soft matter centered research areas which will be unified by general theme of characterization of hierarchically structured multicomponent, multifunctional soft materials: Molecular Characterization, Processing and Mechanics, Thin Films and Interfacial Analysis, and Nanostructure Characterization.

Proper citation: Texas A and M University Soft Matter Core Facility (RRID:SCR_022482) Copy   

•   Source: SciCrunch Registry

http://unmc.edu/radiology/research/bioimaging-core-facility

Provides infrastructure for imaging based small animal research.Includes noninvasive anatomy, physiology, and biochemistry assessment for disease detection and therapeutic monitoring.

Proper citation: University of Nebraska Medical Center Bioimaging Core Facility (RRID:SCR_022481) Copy   

•   Source: SciCrunch Registry