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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://www.bioconductor.org/packages/release/bioc/html/metahdep.html
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 18,2025. Software tools for meta-analysis in the presence of hierarchical (and/or sampling) dependence, including with gene expression studies.
Proper citation: metahdep (RRID:SCR_001225) Copy
http://www.bioconductor.org/packages/release/bioc/html/genArise.html
An easy to use software tool for dual color microarray data. Its GUI-Tk based environment lets any non-experienced user perform a basic, but not simple, data analysis just following a wizard. In addition it provides some tools for the developer.
Proper citation: genArise (RRID:SCR_001346) Copy
http://www.bioconductor.org/packages/release/bioc/html/categoryCompare.html
A software package for meta-analysis of high-throughput experiments using feature annotations. It calculates significant annotations (categories) in each of two (or more) feature (i.e. gene) lists, determines the overlap between the annotations, and returns graphical and tabular data about the significant annotations and which combinations of feature lists the annotations were found to be significant. Interactive exploration is facilitated through the use of RCytoscape (heavily suggested).
Proper citation: categoryCompare (RRID:SCR_001223) Copy
http://www.bioconductor.org/packages/release/bioc/html/BAC.html
R software package that uses a Bayesian hierarchical model to detect enriched regions from ChIP-chip experiments.
Proper citation: BAC (RRID:SCR_001067) Copy
http://www.bioconductor.org/packages/release/data/annotation/html/targetscan.Hs.eg.db.html
R software that predicts biological targets of miRNAs by searching for the presence of conserved 8mer and 7mer sites that match the seed region of each miRNA.
Proper citation: targetscan.Hs.eg.db (RRID:SCR_001068) Copy
http://www.bioconductor.org/packages/release/bioc/html/globaltest.html
A software package that tests groups of covariates (or features) for association with a response variable. The package implements the test with diagnostic plots and multiple testing utilities, along with several functions to facilitate the use of this test for gene set testing of GO and KEGG terms.
Proper citation: globaltest (RRID:SCR_001256) Copy
http://www.bioconductor.org/packages/2.12/bioc/html/rGADEM.html
R package with tools for de novo motif discovery in large-scale genomic sequence data.
Proper citation: rGADEM (RRID:SCR_001091) Copy
http://www.bioconductor.org/packages/2.14/bioc/html/MinimumDistance.html
Software package for analysis of de novo copy number variants in trios from high-dimensional genotyping platforms.
Proper citation: MinimumDistance (RRID:SCR_001260) Copy
https://www.bioconductor.org/packages//2.7/bioc/html/plateCore.html
Software that provides basic S4 data structures and routines for analyzing plate based flow cytometry data.
Proper citation: plateCore (RRID:SCR_001743) Copy
http://bios.unc.edu/~weisun/software/asSeq.htm
Software that establishes a statistical framework for future developments of eQTL (expression quantitative trait locus) mapping methods using RNA-seq data (e.g., linkage-based eQTL mapping), and the joint study of multiple genetic markers and/or multiple genes. This R package has been submitted to R/bioconductor. It will be available on bioconductor soon. It is recommended to install this R package from bioconductor. You can also install this R package from the source code by yourself. Since the R package contains C code, a C complier is required for installation. With both R and appropriate c complier installed, this R package can be installed using the following command (in Mac Terminal window or Windows command window) R CMD INSTALL asSeq
Proper citation: asSeq (RRID:SCR_001625) Copy
https://bioconductor.org/packages/biomaRt/
Software package that integrates BioMart data resources with data analysis software in Bioconductor. Can annotate range of gene or gene product identifiers including Entrez Gene and Affymetrix probe identifiers with information such as gene symbol, chromosomal coordinates, Gene Ontology and OMIM annotation. Enables retrieval of genomic sequences and single nucleotide polymorphism information, which can be used in data analysis.
Proper citation: biomaRt (RRID:SCR_019214) Copy
https://www.bioconductor.org/packages/release/bioc/html/GSVA.html
Open source software R package for assaying variation of gene set enrichment over sample population.Used for microarray and RNA-seq data analysis. Gene set enrichment method that estimates variation of pathway activity over sample population in unsupervised manner.
Proper citation: GSVA (RRID:SCR_021058) Copy
https://bioconductor.org/packages/ReactomePA/
Software R package provides functions for pathway analysis based on REACTOME pathway database. It implements enrichment analysis, gene set enrichment analysis and several functions for visualization.
Proper citation: ReactomePA (RRID:SCR_019316) Copy
https://bioconductor.org/packages/MSnbase/
Software R package provides infrastructure for manipulation, processing and visualisation of mass spectrometry and proteomics data, ranging from raw to quantitative and annotated data. Used for isobaric tagged mass spectrometry data visualization, processing and quantitation.
Proper citation: MSnbase (RRID:SCR_019317) Copy
https://bioconductor.org/packages/release/bioc/html/PhenStat.html
Software R package for statistical analysis of phenotypic data.Tool kit for standardized analysis of high throughput phenotypic data.
Proper citation: PhenStat (RRID:SCR_021317) Copy
https://github.com/PapenfussLab/svaNUMT
Software R package for Nuclear Mitochondrial integration events NUMT detection using structural variant calls.
Proper citation: svaNUMT (RRID:SCR_021381) Copy
https://bioconductor.org/packages/SimFFPE/
Software R package to simulate artifact chimeric reads specifically generated in next generation sequencing process of formalin fixed paraffin embedded tissue. Simulates normal reads as well as artifact chimeric reads that are enriched in FFPE samples. These artifact chimeric reads can lead to large amounts of false positive structural variant calls.
Proper citation: SimFFPE (RRID:SCR_021085) Copy
https://github.com/powellgenomicslab/ascend
Software R package for analysis of single cell RNA-seq expression, normalization and differential expression data. Provides framework to perform cell and gene filtering, quality control, normalization, dimension reduction, clustering, differential expression, and visualization functions.
Proper citation: ascend (RRID:SCR_017257) Copy
Software R package as search tool for single cell RNA-seq data by gene lists. Builds index from scRNA-seq datasets which organizes information in suitable and compact manner so that datasets can be very efficiently searched for either cells or cell types in which given list of genes is expressed.
Proper citation: Scfind (RRID:SCR_017339) Copy
https://bioconductor.org/packages/StructuralVariantAnnotation/
Software R package for structural variant analysis. Contains helper functions for dealing with structural variants in VCF format. Contains functions for parsing VCFs from number of popular callers as well as functions for dealing with breakpoints involving two separate genomic loci encoded as GRanges objects.
Proper citation: StructuralVariantAnnotation (RRID:SCR_018683) Copy
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