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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Gene Weaver
 
Resource Report
Resource Website
10+ mentions
Gene Weaver (RRID:SCR_003009) data analysis service, analysis service resource, data repository, database, storage service resource, production service resource, service resource, data or information resource Freely accessible phenotype-centered database with integrated analysis and visualization tools. It combines diverse data sets from multiple species and experiment types, and allows data sharing across collaborative groups or to public users. It was conceived of as a tool for the integration of biological functions based on the molecular processes that subserved them. From these data, an empirically derived ontology may one day be inferred. Users have found the system valuable for a wide range of applications in the arena of functional genomic data integration. phenotype, microarray, gene, genome, functional genomics, process, pathway, function, gene set, genomic data integration, analysis, visualization is used by: NIF Data Federation
is used by: Integrated Datasets
is listed by: OMICtools
is related to: Integrated Manually Extracted Annotation
has parent organization: Jackson Laboratory
Integrative Neuroscience Initiative on Alcoholism ;
NIAAA U01 AA13499;
NIAAA U24 AA13513;
NIAAA R01 AA18776
PMID:22080549
PMID:19733230
Free, Freely available r3d100012464, OMICS_02232, nif-0000-00517 http://ontologicaldiscovery.org/
https://doi.org/10.17616/R3248T
SCR_003009 GeneWeaver, GeneWeaver - A system for the integration of functional genomics experiments, Ontological Discovery Environment, GeneWeaver.org 2026-02-16 09:45:56 34
VMD
 
Resource Report
Resource Website
1+ mentions
VMD (RRID:SCR_004905) PAMGO_VMD, VMD data analysis service, analysis service resource, database, production service resource, service resource, data or information resource THIS RESOURCE IS NO LONGER IN SERVICE, documented on July 15, 2013. Database covering a range of plant pathogenic oomycetes, fungi and bacteria primarily those under study at Virginia Bioinformatics Institute. The data comes from different sources and has genomes of 3 oomycetes pathogens: Phytophthora sojae, Phytophthora ramorum and Hyaloperonospora arabidopsidis. The genome sequences (95 MB for P.sojae and 65 MB for P.ramorum) were annotated with approximately 19,000 and approximately 16,000 gene models, respectively. Two different statistical methods were used to validate these gene models, Fickett''''s and a log-likelihood method. Functional annotation of the gene models is based on results from BlastX and InterProScan screens. From the InterProScan results, putative functions to 17,694 genes in P.sojae and 14,700 genes in P.ramorum could be assigned. An easy-to-use genome browser was created to view the genome sequence data, which opens to detailed annotation pages for each gene model. A community annotation interface is available for registered community members to add or edit annotations. There are approximately 1600 gene models for P.sojae and approximately 700 models for P.ramorum that have already been manually curated. A toolkit is provided as an additional resource for users to perform a variety of sequence analysis jobs. microbial genome sequence, genome, genome sequence, genome model, gene, image, oomycete, fungus, bacteria, phytophthora sojae, phytophthora ramorum, hyaloperonospora arabidopsidis, plant is used by: NIF Data Federation
is related to: AmiGO
has parent organization: Virginia Polytechnic Institute and State University; Virginia; USA
USDA Cooperative State Research Education and Extension Service 2002-35600-12747;
USDA Cooperative State Research Education and Extension Service 2004-35600-15055;
NSF MCB-0242131;
NSF EF-0412213;
NSF DBI-0211863
PMID:16381891 THIS RESOURCE IS NO LONGER IN SERVICE nlx_87328 http://phytophthora.vbi.vt.edu SCR_004905 VBI Microbial Database, Virginia Bioinformatics Institute Microbial Database 2026-02-16 09:46:32 8
SOURCE
 
Resource Report
Resource Website
50+ mentions
SOURCE (RRID:SCR_005799) SOURCE data analysis service, analysis service resource, database, production service resource, service resource, data or information resource SOURCE compiles information from several publicly accessible databases, including UniGene, dbEST, UniProt Knowledgebase, GeneMap99, RHdb, GeneCards and LocusLink. GO terms associated with LocusLink entries appear in SOURCE. The mission of SOURCE is to provide a unique scientific resource that pools publicly available data commonly sought after for any clone, GenBank accession number, or gene. SOURCE is specifically designed to facilitate the analysis of large sets of data that biologists can now produce using genome-scale experimental approaches Platform: Online tool genomic, functional annotation, ontology, gene expression, gene, genome, statistical analysis, bio.tools, FASEB list is listed by: Gene Ontology Tools
is listed by: Debian
is listed by: bio.tools
is related to: Gene Ontology
has parent organization: SMD
NIGMS ;
NCI CA85129-04;
NIGMS GM07365
PMID:12519986 Restricted biotools:source, nlx_149287 https://login.stanford.edu/idp/profile/SAML2/Redirect/SSO?execution=e1s1
https://bio.tools/source
SCR_005799 2026-02-16 09:46:41 69
PLEXdb - Plant Expression Database
 
Resource Report
Resource Website
10+ mentions
PLEXdb - Plant Expression Database (RRID:SCR_006963) PLEXdb data analysis service, analysis service resource, data repository, database, storage service resource, topical portal, portal, production service resource, service resource, data or information resource PLEXdb (Plant Expression Database) is a unified gene expression resource for plants and plant pathogens. PLEXdb is a genotype to phenotype, hypothesis building information warehouse, leveraging highly parallel expression data with seamless portals to related genetic, physical, and pathway data. The integrated tools of PLEXdb allow investigators to use commonalities in plant biology for a comparative approach to functional genomics through use of large-scale expression profiling data sets. gene expression, plant, plant pathogen, genotype, phenotype, genetic, physical, pathway, plant biology, compare, functional genomics, expression profiling, expression atlas, pathogen, genome, anova, cluster, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: FuncExpression
has parent organization: Iowa State University; Iowa; USA
UniNSF DBI-0543441;
NSF IOS-0922746;
USDA 3625-21000-049-00D
PMID:22084198 biotools:plexdb, r3d100011516, nlx_149236 https://bio.tools/plexdb
https://doi.org/10.17616/R39D13
SCR_006963 PLEXdb - Gene expression resources for plants and plant pathogens, Plant Expression Database 2026-02-16 09:46:51 21
Genetic and Rare Diseases Information Center
 
Resource Report
Resource Website
10+ mentions
Genetic and Rare Diseases Information Center (RRID:SCR_008695) GARD data or information resource, topical portal, disease-related portal, portal Genetic and Rare Diseases Information Center (GARD) is a collaborative effort of two agencies of the National Institutes of Health, The Office of Rare Diseases Research (ORDR) and the National Human Genome Research Institute (NHGRI) to help people find useful information about genetic conditions and rare diseases. GARD provides timely access to experienced information specialists who can furnish current and accurate information about genetic and rare diseases. So far, GARD has responded to 27,635 inquiries on about 7,147 rare and genetic diseases. Requests come not only from patients and their families, but also from physicians, nurses and other health-care professionals. GARD also has proved useful to genetic counselors, occupational and physical therapists, social workers, and teachers who work with people with a genetic or rare disease. Even scientists who are studying a genetic or rare disease and who need information for their research have contacted GARD, as have people who are taking part in a clinical study. Community leaders looking to help people find resources for those with genetic or rare diseases and advocacy groups who want up-to-date disease information for their members have contacted GARD. And members of the media who are writing stories about genetic or rare diseases have found the information GARD has on hand useful, accurate and complete. GARD has information on: :- What is known about a genetic or rare disease. :- What research studies are being conducted. :- What genetic testing and genetic services are available. :- Which advocacy groups to contact for a specific genetic or rare disease. :- What has been written recently about a genetic or rare disease in medical journals. GARD information specialists get their information from: :- NIH resources. :- Medical textbooks. :- Journal articles. :- Web sites. :- Advocacy groups, and their literature and services. :- Medical databases. genetic, disease, information, genome, human, rare disease, health, physician, counselor, gene, journal, medical has parent organization: National Institutes of Health Office of Rare Diseases Research ;
NHGRI
nif-0000-37627 SCR_008695 Genetic Rare Diseases Information Center 2026-02-16 09:47:15 14
BBmap
 
Resource Report
Resource Website
500+ mentions
BBmap (RRID:SCR_016965) software application, data processing software, software toolkit, image analysis software, software resource, alignment software Software tool as a short read aligner for DNA and RNA seq data. Used for large genomes with millions of scaffolds. Can align reads from Illumina, PacBio, 454, Sanger, Ion Torrent, Nanopore. Fast and accurate, particularly with highly mutated genomes or reads with long indels, even whole gene deletions over 100kbp long. It has no upper limit to genome size or number of contigs. Written in Java, can run on any platform. Joint Genome Institute, short, read, aligner, DNA, RNA, sequencing, data, large, genome, scaffold, mutated, long, indel is listed by: Bestus Bioinformaticus Tools
is listed by: Debian
is related to: University of California at Berkeley; Berkeley; USA
Free, Available for download, Freely available https://jgi.doe.gov/data-and-tools/bbtools/bb-tools-user-guide/bbmap-guide/
https://sources.debian.org/src/bbmap/
SCR_016965 2026-02-16 09:49:08 797
TopDom
 
Resource Report
Resource Website
10+ mentions
TopDom (RRID:SCR_016964) TOPDOM software application, data processing software, software toolkit, data analysis software, software resource Software tool to identify Topological Domains, which are basic builiding blocks of genome structure. Detects topological domains in a linear time., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. identify, topological, domain, genome, structure, linear, time, data, analysis has parent organization: University of Southern California; Los Angeles; USA
works with: CCTOP
NHLBI U01 HL108634;
NIDDK U54 DK107981;
NSF CAREER 0747475;
NSF CAREER 1150287;
Arnold and Mabel Beckman foundation ;
Pew Charitable Trusts
PMID:26704975 THIS RESOURCE IS NO LONGER IN SERVICE SCR_016964 TOPological DOMains, Topological Domains, TopDom_v0.0.2, TopDom_v0.0.1 2026-02-16 09:49:08 10
KAT
 
Resource Report
Resource Website
10+ mentions
KAT (RRID:SCR_016741) KAT software application, data processing software, software toolkit, data analysis software, software resource Software that generates, analyses and compares k-mer spectra produced from sequence files. Used to quality control NGS datasets and genome assemblies. generate, analyse, compare, k-mer, spectra, sequence, file, quality, control, NGS, dataset, genome, assembly, bio.tools is listed by: Debian
is listed by: bio.tools
BBSRC DOI:10.1093/bioinformatics/btw663 Free, Available for download, Freely available biotools:kat http://www.earlham.ac.uk/kat-tools
https://bio.tools/kat
SCR_016741 K-mer Analysis Toolkit 2026-02-16 09:49:05 19
Flye
 
Resource Report
Resource Website
100+ mentions
Flye (RRID:SCR_017016) software application, data processing software, software toolkit, sequence analysis software, data analysis software, software resource Software package as de novo assembler for single molecule sequencing reads. Used for assembling long, error prone reads such as those produced by PacBio and Oxford Nanopore Technologies, for fast and accurate genome reconstructions. Available for Linux and MacOS platforms. assembler, single, molecule, sequencing, long, error, read, fast, accurate, genome, reconstruction, nucleotide, quality, data, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: University of California at San Diego; California; USA
PMID:27956617 Free, Available for download, Freely available biotools:Flye https://bio.tools/Flye
https://sources.debian.org/src/flye/
SCR_017016 2026-02-16 09:49:08 267
matemaker
 
Resource Report
Resource Website
1+ mentions
matemaker (RRID:SCR_017199) software application, data processing software, sequence analysis software, data analysis software, software resource, standalone software Software tool to make artificial mate pairs from long sequences for scaffolding. artificial, mate, pair, long, sequence, scaffolding, genomics, genome, assembly Free, Available for download, Freely available SCR_017199 matemaker v1.0.0 2026-02-16 09:49:11 4
RNAmmer
 
Resource Report
Resource Website
100+ mentions
RNAmmer (RRID:SCR_017075) software application, data processing software, web service, data analysis software, data analysis service, analysis service resource, data access protocol, software resource, production service resource, service resource, standalone software Software package to predict ribosomal RNA genes in full genome sequences by utilising two levels of Hidden Markov Models. Consistent and rapid annotation of ribosomal RNA genes. predict, ribosomal, RNA, gene, full, genome, sequence, HMM, rRNA has parent organization: Technical University of Denmark; Lyngby; Denmark EMBIO at the University of Oslo ;
Research Council of Norway ;
Danish Center for Scientific Computing ;
European Union
PMID:17452365 Restricted SCR_017075 2026-02-16 09:49:09 103
Maize Database of Images and Genomes
 
Resource Report
Resource Website
1+ mentions
Maize Database of Images and Genomes (RRID:SCR_016987) MaizeDIG analysis service resource, database, production service resource, service resource, data or information resource Genotype and phenotype database for maize images based on BioDIG. Supports multiple reference genomes and has been integrated with the MaizeGDB Genome Browser to make custom tracks showing mutant phenotypes within their genomic context. Allows for custom tagging of images to highlight regions related to the phenotypes. This is accomplished through an interface allowing users to create links from images to genomic coordinates and to curate and search images by gene model ID, gene symbol, and gene name. genotype, phenotype, collection, maize, image, reference, genome works with: MaizeGDB Free, Freely available SCR_016987 Maize Dig, MaizeDatabase of Images and Genomes, MaizeDig, MaizeDIG 2026-02-16 09:49:08 5
WTDBG
 
Resource Report
Resource Website
50+ mentions
WTDBG (RRID:SCR_017225) software application, data processing software, sequence analysis software, data analysis software, image analysis software, software resource, alignment software Software tool as de novo sequence assembler for long noisy reads produced by PacBio or Oxford Nanopore Technologies. It assembles raw reads without error correction and then builds consensus from intermediate assembly output. Desiged to assemble huge genomes in very limited time. sequence, assembler, de novo, long, noisy, read, likelihood, estimator, genome is listed by: OMICtools
is listed by: Debian
NSFC ;
NHGRI R01 HG010040
PMID:31819265 Free, Available for download, Freely available OMICS_24025 https://github.com/ruanjue/wtdbg
https://sources.debian.org/src/wtdbg2/
SCR_017225 Wtdbg2, wtdgb, Wtdgb, wtdgb2 2026-02-16 09:49:11 57
MCScan
 
Resource Report
Resource Website
10+ mentions
MCScan (RRID:SCR_017650) software application, data processing software, software toolkit, sequence analysis software, data analysis software, software resource Software package to simultaneously scan multiple genomes to identify homologous chromosomal regions and subsequently align these regions using genes as anchors.Used to identify conserved gene arrays both within same genome and across different genomes. Command line program to wrap dagchainer and combine pairwise results into multi alignments in column format. Simultaneously, scan, multiple, genome, identify, homologous, chromosomal, region, align, gene, anchor, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: University of Georgia; Georgia; USA
Free, Available for downoad, Freely available biotools:MCScan http://chibba.agtec.uga.edu/duplication/mcscan/
https://bio.tools/MCScan
SCR_017650 Multiple Collinearity Scan 2026-02-16 09:49:17 37
Blobtools
 
Resource Report
Resource Website
100+ mentions
Blobtools (RRID:SCR_017618) software application, data processing software, data analytics software, data visualization software, software resource Software tool as modular command line solution for visualisation, quality control and taxonomic partitioning of genome datasets. Used for interrogation of genome assemblies. Assists in primary partitioning of data, leading to improved assemblies, and screening of final assemblies for potential contaminants. Modular, command, line, solution, visualisation, quality, control, taxonomic, partitioning, genome, dataset, genome assembly, screening, contaminant, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: BlobTools2
James Hutton Institute/Edinburgh University School of Biological Sciences fellowship ;
BBSRC
DOI:10.12688/f1000research.12232.1 Free, Available for download, Freely available biotools:blobtools https://github.com/DRL/blobtools
https://bio.tools/blobtools
SCR_017618 BlobTools 2026-02-16 09:49:17 199
Ngmlr
 
Resource Report
Resource Website
10+ mentions
Ngmlr (RRID:SCR_017620) NGMLR software application, data processing software, image analysis software, software resource, alignment software Software tool as long read mapper designed to align PacBio or Oxford Nanopore reads to reference genome and optimized for structural variation detection. Long, read, mapper, align, PacBio, Oxford Nanopore, read, reference, genome, structural, variantion, detection, bio.tools is listed by: bio.tools
is listed by: Debian
National Science Foundation ;
NHGRI R01 HG006677;
NHGRI UM1 HG008898
PMID:29713083 Free, Available for download, Freely available biotools:ngmlr https://bio.tools/ngmlr SCR_017620 coNvex Gap-cost alignMent for Long Reads 2026-02-16 09:49:16 31
refgenie
 
Resource Report
Resource Website
1+ mentions
refgenie (RRID:SCR_017574) service resource, software application, software resource, data management software Software tool to organize, retrieve, and share genome analysis resources. Reference genome assembly asset manager. In addition to genome indexes, can manage any files related to reference genomes, including sequences and annotation files. Includes command line interface and server application that provides RESTful API, so it is useful for both tool development and analysis. Organize, retrive, share, genome, analysis, reference, assembly, asset, manager, sequence, annotation, file, command, line, interface, bio.tools is listed by: Debian
is listed by: bio.tools
DOI:10.1101/698704 Free, Available for download, Freely available biotools:Refgenie https://bio.tools/Refgenie SCR_017574 reference genome manager 2026-02-16 09:49:16 6
CRISPy-web
 
Resource Report
Resource Website
10+ mentions
CRISPy-web (RRID:SCR_017970) data access protocol, software resource, web service Web tool to design sgRNAs for CRISPR applications. Web tool based on CRISPy to design sgRNAs for any user-provided microbial genome. Implemented as standalone web application for Cas9 target prediction. Design, sgRNA, CRISP, microbial, genome, Cas9, target, prediction, data, guide, single, editing, bio.tools is listed by: bio.tools
is listed by: Debian
Novo Nordisk Foundation PMID:29062934 Free, Freely available biotools:crispy https://bio.tools/crispy SCR_017970 single guide RNA desing 2026-02-16 09:49:23 25
PAFScaff
 
Resource Report
Resource Website
1+ mentions
PAFScaff (RRID:SCR_017976) software application, data processing software, sequence analysis software, data analysis software, software resource Software as Pairwise mApping Format reference based Scaffold anchoring and super scaffolding tool. Dsigned for mapping genome assembly scaffolds to closely related chromosome level reference genome assembly. Pairwise, mapping, reference, scaffold, genomics, scaffolding, assembly, genome, chromosome, bio.tools is listed by: Debian
is listed by: bio.tools
Free, Freely available biotools:PAFScaff https://github.com/slimsuite/pafscaff/blob/master/PAFScaff.md
https://slimsuite.github.io/pafscaff/
https://bio.tools/PAFScaff
SCR_017976 Pairwise mApping Format reference-based Scaffold 2026-02-16 09:49:23 4
rVista
 
Resource Report
Resource Website
10+ mentions
rVista (RRID:SCR_018707) web service, data access protocol, analysis service resource, software resource, production service resource, service resource Web tool for analyzing regulatory potential of noncoding sequences. rVISTA web server is interconnected with TRANSFAC database, allowing users to either search for matrices present in TRANSFAC library collection or search for user defined consensus sequences. rVISTA 2.0 web server is used for high throughput discovery of cis-regulatory elements. Can process alignments generated by zPicture and blastz alignment programs or use pre-computed pairwise alignments of several vertebrate genomes available from ECR Browser and GALA database. Evolutionary analysis of transcription factor binding sites. Noncoding sequence, regulatory potential analysis, matrices search, TRANSFAC library collection, cis regulatory element, process alignment, zPicture, blastz, pairwise alignment, genome, analysis, transcription factor binding site, bio.tools is listed by: Debian
is listed by: bio.tools
works with: TRANSFAC
PMID:15215384 Free, Freely available biotools:rvista https://bio.tools/rvista SCR_018707 rVista 2.0 2026-02-16 09:49:33 30

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