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https://www.cincinnatichildrens.org/research/cores/translational-core-laboratory/cell-processing-core

Supplies mononuclear cells, stem cells or other enriched cell populations. Provides stem cells and other tissue samples from normal donor or patient populations such as disease specific repositories or specific research studies requiring sample processing. Samples are provided fresh or cryopreserved according to availability, unprocessed or with further lab processing.Common processing techniques include PBMC isolation,Serum and plasma isolation,Separation of marker specific populations,Flow cytometric characterization of samples,Interferon gamma EliSpot.Additional services may be available upon request

Proper citation: Cincinnati Children's Hospital Cell Processing Core Facility (RRID:SCR_022623) Copy   

•   Source: SciCrunch Registry

https://www.unmc.edu/vcr/cores/vcr-cores/camri/index.html

Provides research MRI capabilities for investigators at UNMC and across greater Omaha area. Housed in Hixson-Lied Center, CAMRI operates Siemens 3T Prisma MRI instrument that can collect high quality data of any MR modality using advanced gradients and research grade pulse sequences. Variety of head coils (20-, 32-, and 64-channel) are available to optimize data collection for needs of specific studies. Studies incorporating functional MRI can take advantage of CAMRI�s suite of MRI-compatible response devices, mirrored 32-inch LCD screen, and integrated stimulus display computer.

Proper citation: University of Nebraska Medical Center Advanced Magnetic Resonance Imaging Core Facility (RRID:SCR_022468) Copy   

•   Source: SciCrunch Registry

https://www.unmc.edu/vcr/cores/vcr-cores/confocal-microscopy/index.html

Facility houses imaging technologies ranging from super resolution (~ 0.120 um to 0.020 um) to microscopic (~ 0.300 um) to mesoscopic (~ 1 um) biomedical imaging. Imaging specialists provide training and/or actively assist researchers collecting images across imaging instrumentation. Instrumentation includes Zeiss ELYRA PS.1 is inverted microscope for super resolution (SR) structured illumination microscopy (SIM) and single molecule localization microscopy (SMLM) including, PhotoActivated Localization Microscopy (PALM) using photo switchable/convertible fluorescent proteins, Total Internal Reflection Fluorescence (TIRF) and STochastic Optical Reconstruction Microscopy (STORM);Zeiss 800 CLSM with Airyscan is an inverted microscope dramatically increasing conventional confocal image resolution to ~180 nm using Airyscan technology; Zeiss 710 LSM is inverted microscope supporting most basic imaging applications, multi channel and spectral, co localization, live cell, 3D, and time series imaging; Zeiss Celldiscoverer 7 is widefield imaging system for automated, time lapse imaging of live samples; Zeiss Axioscan 7 is high performance whole slide scanning system for fluorescence, brightfield, and polarization imaging;Miltenyi Biotec Ultramicroscope II Light Sheet fluorescence microscope (LSFM) extends fluorescent imaging into true 3D, large scale volumetric imaging of intact tissues, organs, and small organisms. AMCF also houses several high-end data analysis workstations with premier image analysis software including HALO (Indica Labs) and IMARIS (Oxford Instruments) facilitating data rendering, analyses, and presentation options.

Proper citation: University of Nebraska Medical Center Advanced Microscopy Core Facility (RRID:SCR_022467) Copy   

•   Source: SciCrunch Registry

https://www.cincinnatichildrens.org/research/cores/animal

Offers behavioral phenotyping of rodent models as well as characterizing nervous system function in mouse and rat models through behavioral assays.

Proper citation: Cincinnati Children's Hospital Animal Behavior Core Facility (RRID:SCR_022621) Copy   

•   Source: SciCrunch Registry

http://www.ohri.ca/bioinformatics

Core of University of Ottawa and Ottawa Hospital Research Institute. Provides advice on bioinformatics research design, conduct bioinformatics analysis, and provide support for grant proposals that involve bioinformatics (including conducting pilot studies, support/collaboration letters and methodological text). Areas of expertise include:Analysis of high throughput sequencing data; single cell (Chromium 10x), RNA-seq (including small RNA), ChIP-seq, ATAC-seq, Hi-C.Large scale analysis integrating multiple data types.Helps to arrange for analysis of your biological samples with local core facilities such as StemCore, Proteomics Resource Center, or OHRI Mass Spectrometry Core Facility. Provides yearly training courses in RNA-seq analysis and Bioinformatics analysis using R as well as individual training and analysis support on request.

Proper citation: University of Ottawa Bioinformatics Core Facility (RRID:SCR_022466) Copy   

•   Source: SciCrunch Registry

https://www.cincinnatichildrens.org/research/divisions/d/dhc/cores/integrative-morphology/confocal-imaging

Provides Cincinnati Children s Hospital Medical Center; Cincinnati; Ohio resources in confocal, wide-field, and spatial technique applications.

Proper citation: Cincinnati Children's Hospital Confocal Imaging Core Facility (RRID:SCR_022628) Copy   

•   Source: SciCrunch Registry

http://bioinf.itmat.upenn.edu/

Provides project based bioinformatics support for ITMAT translational researchers. Provides computational infrastructure and programming support needed to conduct high-throughput proteomics experiments. We also support other genomics high-throughput technologies to a lesser extent. The projects range from building Web applications for data analysis pipelines, scripting, clinical and basic science research support, and database and algorithm development. Recent efforts have focused on explorations of new models of computation, specifically cloud computing and GPUs, for use in genomic scale research.

Proper citation: University of Pennsylvania Perelman School of Medicine ITMAT Bioinformatics Laboratory Core Facility (RRID:SCR_022486) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/CMSDLD/biomedical-data-science-core-bdsc.html

Core provides consultations and fee for service support in big data analyses using methods of data science in biomedical and health research related to digestive disease and liver research.

Proper citation: University of Pennsylvania Perelman School of Medicine Biomedical Data Science Core Facility (RRID:SCR_022485) Copy   

•   Source: SciCrunch Registry

https://somf.engr.tamu.edu/

Facility is focused on characterization of multifunctional soft materials. Includes four instrumentation suites based on soft matter centered research areas which will be unified by general theme of characterization of hierarchically structured multicomponent, multifunctional soft materials: Molecular Characterization, Processing and Mechanics, Thin Films and Interfacial Analysis, and Nanostructure Characterization.

Proper citation: Texas A and M University Soft Matter Core Facility (RRID:SCR_022482) Copy   

•   Source: SciCrunch Registry

http://unmc.edu/radiology/research/bioimaging-core-facility

Provides infrastructure for imaging based small animal research.Includes noninvasive anatomy, physiology, and biochemistry assessment for disease detection and therapeutic monitoring.

Proper citation: University of Nebraska Medical Center Bioimaging Core Facility (RRID:SCR_022481) Copy   

•   Source: SciCrunch Registry

https://www.cincinnatichildrens.org/research/cores/pathology-core

Provides technical support for routine morphology based techniques. Pathologists are on hand to help guide projects, interpret results and collaborate on publications. Core personnel provide technical support for routine morphology based techniques including tissue processing and embedding, routine and special histochemical staining, immunohistochemistry, in situ hybridization, and electron microscopy.

Proper citation: Cincinnati Children's Hospital Pathology Research Core Facility (RRID:SCR_022637) Copy   

•   Source: SciCrunch Registry

https://www.cincinnatichildrens.org/research/cores/metabolomics

Provides all NMR related metabolomics services on human and animal cells, biopsies and body fluids.

Proper citation: Cincinnati Children's Hospital NMR based Metabolomics Core Facility (RRID:SCR_022636) Copy   

•   Source: SciCrunch Registry

https://www.cincinnatichildrens.org/research/cores/flow-cytometry

Shared resource lab for flow cytometry instrumentation, training, education and analyte measurement (ELISA, Luminex, IsoLight). New users need to be trained for their instrument of choice.

Proper citation: Cincinnati Children's Hospital Research Flow Cytometry Core Facility (RRID:SCR_022635) Copy   

•   Source: SciCrunch Registry

https://www.cincinnatichildrens.org/research/cores/pluripotent-stem-cell-facility

Supports all aspects of human pluripotent stem cell research, providing access to well characterized human embryonic stem cells and induced pluripotent stem cells for distribution to researchers. Consists of tissue culture facilities, access to microscopy and histology equipment, as well as equipment for cellular and molecular analysis of hESCs.

Proper citation: Cincinnati Children's Hospital Pluripotent Stem Cell Core Facility (RRID:SCR_022634) Copy   

•   Source: SciCrunch Registry

https://vetmed.tamu.edu/ial/

Provides advanced imaging technologies and image analysis tools including vital imaging of cellular processes within cells, tissue explants, and organoids.Supports services for transmission electron microscopy of biological samples.Imaging capabilities include fluorescence imaging of samples;Transmitted light imaging; Live cell imaging;FRAP, FLIP, Photoactivation/conversion;FRET, FLIM; Image processing, analysis, quantification; Transmission electron microscopy.Microscopes and Equipment include:Zeiss Axio Imager M2 Motorized Upright Microscope;Zeiss Cell Discoverer 7; Zeiss ELYRA S.1 Superresolution Microscope; Zeiss LSM 780 NLO Multiphoton Microscope;Zeiss TIRF3;Zeiss Stallion Digital Imaging Workstation;FEI Morgagni Transmission Electron Microscope;Leica UC6 Ultramicrotome;ImageXpress Pico & BioTek Cytation 7;Cryostar NX70 Cryostat.

Proper citation: Texas A and M University Image Analysis Laboratory Core Facility (RRID:SCR_022479) Copy   

•   Source: SciCrunch Registry

https://www.cincinnatichildrens.org/research/support/clinical-translational-research

Clinical research support center for investigators and industry sponsors.Provides support services, research tools, experienced research personnel, and facilities to conduct or facilitate pediatric and adult clinical research from identification and development of research opportunities to phase I through phase IV clinical research trials.

Proper citation: Cincinnati Children's Hospital Office for Clinical and Translational Research Core Facility (RRID:SCR_022633) Copy   

•   Source: SciCrunch Registry

https://www.cincinnatichildrens.org/research/cores/translational-core-laboratory/vector-production-facility

Facility manufactures lentiviral and retroviral vectors in support of early phase clinical trials.Services include large scale GMP lentiviral and retroviral vector and small to mid scale GMP like manufactured products. Supports certification and stability studies.

Proper citation: Cincinnati Children's Hospital Vector Production Core Facility (RRID:SCR_022639) Copy   

•   Source: SciCrunch Registry

https://www.utsouthwestern.edu/labs/qlmc/

Provides access to variety of microscope modalities including laser scanning and spinning disk confocal, multiphoton, wide field deconvolution, CFP/YFP FRET, TIRF, single molecule imaging, and more. Offers customized microscopy training, advise and help with sample preparation, image quantification, and offer basic microscope maintenance. Can streamline your data handling and image visualization as well as automate your image analysis workflow through customized Fiji macros.

Proper citation: University of Texas Southwestern Medical Center Quantitative Light Microscopy Core Facility (RRID:SCR_022605) Copy   

•   Source: SciCrunch Registry

https://research.med.psu.edu/core-facilities/metabolic-phenotyping/

Supports research that requires comprehensive assessment of energy balance and body composition in experimental rodents by providing necessary equipment and expertise. Services include training in the use of equipment, consultation on experiment design, and help with data analysis. Instrumentation includes Bruker TD-NMR LF100 Minispec and TSE Phenomaster System with Integrated Stellar Telemetry.

Proper citation: Penn State College of Medicine Metabolic Phenotyping Core Facility (RRID:SCR_022565) Copy   

•   Source: SciCrunch Registry

https://www.museumfuernaturkunde.berlin/en/science/micro-ct-laboratory

Provides analysis of biological, palaeontological and geological objects using computer assisted methods. Center for research at museum and for digitisation of scientific collections. Open to external users. In addition to various devices for three dimensional scanning, laboratory has workstations for processing and analysing raw data using 3D volume processing software.

Proper citation: MfN Berlin Micro-CT Laboratory Core Facility (RRID:SCR_022585) Copy   

•   Source: SciCrunch Registry