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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
deepSNV
 
Resource Report
Resource Website
10+ mentions
deepSNV (RRID:SCR_006214) deepSNV software resource Software package that provides quantitative variant callers for detecting subclonal mutations in ultra-deep (>=100x coverage) sequencing experiments. The algorithm is used for a comparative setup with a control experiment of the same loci and uses a beta-binomial model and a likelihood ratio test to discriminate sequencing errors and subclonal SNVs (single nucleotide variants). data import, genetic variability, genetics, snp, sequencing, single nucleotide variant, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
PMID:24443148 GNU General Public License, v3 OMICS_02239, biotools:deepsnv https://bio.tools/deepsnv SCR_006214 deepSNV - Detection of subclonal SNVs in deep sequencing experiments 2026-02-14 02:01:06 34
PHYLIP
 
Resource Report
Resource Website
1000+ mentions
PHYLIP (RRID:SCR_006244) PHYLIP software resource, source code, data processing software, software application A free package of software programs for inferring phylogenies (evolutionary trees). The source code is distributed (in C), and executables are also distributed. In particular, already-compiled executables are available for Windows (95/98/NT/2000/me/xp/Vista), Mac OS X, and Linux systems. Older executables are also available for Mac OS 8 or 9 systems. phylogeny prediction, evolutionary tree, bio.tools is listed by: bio.tools
is listed by: Debian
is listed by: OMICtools
is listed by: SoftCite
has parent organization: University of Washington; Seattle; USA
works with: PAML
NSF ;
NIGMS ;
DOE
Free nif-0000-06708, OMICS_04240, biotools:phylip https://bio.tools/phylip
https://sources.debian.org/src/phylip/
SCR_006244 PHYLogeny Inference Package 2026-02-14 02:01:04 3519
ScerTF
 
Resource Report
Resource Website
10+ mentions
ScerTF (RRID:SCR_006121) ScerTF data analysis service, analysis service resource, data or information resource, production service resource, service resource, database Catalog of over 1,200 position weight matrices (PWMs) for 196 different yeast transcription factors (TFs). They've curated 11 literature sources, benchmarked the published position-specific scoring matrices against in-vivo TF occupancy data and TF deletion experiments, and combined the most accurate models to produce a single collection of the best performing weight matrices for Saccharomyces cerevisiae. ScerTF is useful for a wide range of problems, such as linking regulatory sites with transcription factors, identifying a transcription factor based on a user-input matrix, finding the genes bound/regulated by a particular TF, and finding regulatory interactions between transcription factors. Enter a TF name to find the recommended matrix for a particular TF, or enter a nucleotide sequence to identify all TFs that could bind a particular region. binding site, transcription factor, regulatory site, gene, regulation, regulatory interaction, matrix, nucleotide sequence, dna sequence, yeast, position weight matrix, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Washington University School of Medicine in St. Louis; Missouri; USA
NIGMS R01 GM078222;
NHGRI HG00249
PMID:22140105 biotools:scertf, nlx_151599, OMICS_00542 http://ural.wustl.edu/ScerTF
https://bio.tools/scertf
http://ural.wustl.edu/TFDB/ SCR_006121 2026-02-14 02:01:03 19
SitEx
 
Resource Report
Resource Website
1+ mentions
SitEx (RRID:SCR_006122) SitEx data analysis service, analysis service resource, data or information resource, production service resource, service resource, database THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 19,2019. Analyzing protein structure projection on exon-intron structure of corresponding gene through years led to several fundamental conclusions about structural and functional organization of the protein. According to these results we decided to map the protein functional sites. So we created the database SitEx that keep the information about this mapping and included the BLAST search and 3D similar structure search using PDB3DScan for the polypeptide encoded by one exon, participating in organizing the functional site. This will help: # to study the positions of the functional sites in exon structure; # to make the complex analysis of the protein function; # to exposure the exons that took part in exon shuffling and came from bacterial genomes; # to study the peculiarities of coding the polypeptide structures. Currently, SitEx contains information about 9994 functional sites presented in 2021 proteins described in proteomes of 17 organisms. projection, protein, functional site, exon, blast, structure, function, gene, amino acid, encoding gene, proteome, ligand, data set, bio.tools is listed by: 3DVC
is listed by: Debian
is listed by: bio.tools
has parent organization: Institute of Cytology and Genetics of the Siberian Branch of the RAS; Novosibirsk; Russia
Ministry of Science and Education 14.740.11.0001;
Ministry of Science and Education 07.514.11.4003;
Interdisciplinary Integrative Project 35 of SB RAS ;
Russian Foundation for Basic Research 11-04-92712;
EU-FP7 260429;
Program of RAS ;
DAAD Leonard Euler Program Grant
PMID:22139920 THIS RESOURCE IS NO LONGER IN SERVICE. biotools:sitex, nlx_151602 https://bio.tools/sitex SCR_006122 SitEx Database 2026-02-14 02:01:13 1
Predictive Networks
 
Resource Report
Resource Website
Predictive Networks (RRID:SCR_006110) PN data analysis service, analysis service resource, data or information resource, production service resource, source code, service resource, software resource, database A flexible, open-source, web-based application and data services framework that enables the integration, navigation, visualization and analysis of gene interaction networks. The primary goal of PN is to allow biomedical researchers to evaluate experimentally derived gene lists in the context of large-scale gene interaction networks. The PN analytical pipeline involves two key steps. The first is the collection of a comprehensive set of known gene interactions derived from a variety of publicly available sources. The second is to use these ''known'' interactions together with gene expression data to infer robust gene networks. The regression-based network inference algorithm creates a graph of gene interactions in which cycles may be present (but no self-loops). Based on information-theoretic techniques, a causal gene interaction network is inferred from both prior knowledge (interactions extracted from biomedical literature and structured biological databases) and gene expression data. A prediction model is fitted for each gene, given its parents, enabling assessment of the predictive ability of the network model. gene interaction network, gene, interaction, gene expression, graph, visualization, gene interaction, gene network, predictive network analysis, model, bio.tools is listed by: 3DVC
is listed by: Debian
is listed by: bio.tools
has parent organization: Dana-Farber Cancer Institute
has parent organization: SourceForge
NLM 1R01LM010129 PMID:22096235 Apache License, v2 nlx_151582, biotools:predictivenetworks https://bio.tools/predictivenetworks SCR_006110 2026-02-14 02:01:13 0
Computerized Anatomical Reconstruction and Editing Toolkit
 
Resource Report
Resource Website
50+ mentions
Computerized Anatomical Reconstruction and Editing Toolkit (RRID:SCR_006260) CARET data visualization software, data processing software, software application, image processing software, software resource Software package to visualize and analyze structural and functional characteristics of cerebral and cerebellar cortex in humans, nonhuman primates, and rodents. Runs on Apple (Mac OSX), Linux, and Microsoft Windows operating systems. reconstruction, visualization, cerebral cortex, surface, brain, dataset, cerebellar cortex, atlas application, mesh generation, quantitative shape analysis, segmentation, shape analysis, intersubject, image-to-template, gaussian curvature, mean curvature, animation, three dimensional display, two dimensional display, surface rendering, cortical flat map, FASEB list is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is listed by: Debian
is related to: SumsDB
has parent organization: Washington University School of Medicine in St. Louis; Missouri; USA
NIMH R01 MH60974;
NEI EY02091
PMID:11522765 Free, Available for download, Freely available nif-0000-00279 http://www.nitrc.org/projects/caret
https://sources.debian.org/src/caret/
SCR_006260 Computerized Anatomical Reconstruction Editing Toolkit 2026-02-14 02:01:04 57
SpliceDisease
 
Resource Report
Resource Website
1+ mentions
SpliceDisease (RRID:SCR_006130) SpliceDisease data repository, storage service resource, data or information resource, service resource, database Curated database of experimentally supported data of RNA Splicing mutation and disease. The RNA Splicing mutations include cis-acting mutations that disrupt splicing and trans-acting mutations that affecting RNA-dependent functions that cause disease. Information such as EntrezGeneID, gene genomic sequence, mutation (nucleotide substitutions, deletions and insertions), mutation location within the gene, organism, detailed description of the splicing mutation and references are also given. Users are able to submit new entries to the database. This database integrating RNA splicing and disease associations would be helpful for understanding not only the RNA splicing but also its contribution to disease. In SpliceDisease database, they manually curated 2337 splicing mutation disease entries involving 303 genes and 370 diseases, which have been supported experimentally in 898 publications. The SpliceDisease database provides information including the change of the nucleotide in the sequence, the location of the mutation on the gene, the reference PubMed ID and detailed description for the relationship among gene mutations, splicing defects and diseases. They standardized the names of the diseases and genes and provided links for these genes to NCBI and UCSC genome browser for further annotation and genomic sequences. For the location of the mutation, they give direct links of the entry to the respective position/region in the genome browser. rna splicing, mutation, disease, gene, genomic sequence, nucleotide substitution, deletion, insertion, mutation location, splicing mutation, nucleotide, disease association, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: Peking University; Beijing; China
National Natural Science Foundation of China 81001481 PMID:22139928 The community can contribute to this resource biotools:splicedisease_db, nlx_151614 https://bio.tools/splicedisease_db SCR_006130 Splice Disease, SpliceDisease Database Site, Splice Disease Database, SpliceDisease Database 2026-02-14 02:01:05 2
ChemSpider
 
Resource Report
Resource Website
1000+ mentions
ChemSpider (RRID:SCR_006360) ChemSpider web service, mobile app, data or information resource, service resource, software application, data access protocol, software resource, database Collection of chemical structures. Provides access to structures, properties and associated information from hundreds of data sources to find compounds of interest and provides services to improve this data by curation and annotation and to integrate it with users applications. collection, chemical, structure, property, data, compound, bio.tools, FASEB list is used by: Open PHACTS
is used by: GEROprotectors
is listed by: re3data.org
is listed by: bio.tools
is listed by: Debian
has parent organization: Royal Society of Chemistry
Waters ;
GGA Software Services
Free, Freely available, Registration required for some sites nlx_152101, biotools:chemspider, r3d100010205 https://bio.tools/chemspider
https://doi.org/10.17616/R38P4P
SCR_006360 2026-02-14 02:01:08 1759
QCGWAS
 
Resource Report
Resource Website
1+ mentions
QCGWAS (RRID:SCR_006408) QCGWAS software resource Software tools for (automated and manual) quality control of the results of Genome Wide Association Studies. quality control, genome wide association study, windows, os x, r, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
PMID:24395754 GNU General Public License, v3 or later OMICS_02203, biotools:qcgwas https://bio.tools/qcgwas SCR_006408 QCGWAS: Quality Control of Genome Wide Association Study results, Quality Control of Genome Wide Association Study 2026-02-14 02:01:09 7
LTR_Finder
 
Resource Report
Resource Website
500+ mentions
LTR_Finder (RRID:SCR_015247) web service, analysis service resource, production service resource, service resource, data access protocol, software resource Web software capable of scanning large-scale sequences for full-length LTR retrotranspsons., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. Long Terminal Repeat retrotransposons, Long Terminal Repeat, retrotransposon prediction, genome sequences, LTR prediction, LTR structure prediction, DNA sequence, biotools is listed by: Debian
is listed by: bio.tools
Fudan University ;
Shanghai ;
China
PMID:17485477 THIS RESOURCE IS NO LONGER IN SERVICE SCR_020944, biotools:ltr_finder https://bio.tools/ltr_finder SCR_015247 LTR Finder 2026-02-14 02:03:01 795
SEER
 
Resource Report
Resource Website
100+ mentions
SEER (RRID:SCR_015499) sequence analysis software, data processing software, data analysis software, source code, software application, software resource Sequence element enrichment analysis tool to perform pan-genome-wide association studies in bacteria. bacterial genome association, sequence element enrichment analysis, kmer enrichment analysis is listed by: Debian
is listed by: OMICtools
is hosted by: GitHub
DOI:10.1038/ncomms12797
DOI:10.1101/038463
Available for download OMICS_21699 https://sources.debian.org/src/seer/ SCR_015499 2026-02-14 02:02:49 463
primers4clades
 
Resource Report
Resource Website
1+ mentions
primers4clades (RRID:SCR_015714) software resource, web application Web application for the design of PCR primers for cross-species amplification of novel sequences from metagenomic DNA or from uncharacterized organisms belonging to user-specified phylogenetic lineages. It implements an extended CODEHOP strategy and evaluates thermodynamic properties of the oligonucleotide pairs. pcr primer, metagenomic dna, phylogenetic lineage, primer, clade, bio.tools is listed by: Debian
is listed by: bio.tools
DGAPA IN201806-2;
CONACyT-Mexico P1-60071;
CSIC 200720I038
PMID:19465390 Freely available, Free for academic use, Tutorial available biotools:primers4clades http://maya.ccg.unam.mx/primers4clades
https://bio.tools/primers4clades
SCR_015714 2026-02-14 02:03:08 2
clustergrammer
 
Resource Report
Resource Website
10+ mentions
clustergrammer (RRID:SCR_015681) data visualization tool, software tool Clustergrammer is a web-based tool for visualizing and analyzing high-dimensional data as interactive and shareable hierarchically clustered heatmaps. Clustergrammer enables intuitive exploration of high-dimensional data and has several optional biology-specific features. bio.tools is listed by: Debian
is listed by: bio.tools
DOI:10.1038/sdata.2017.151 biotools:clustergrammer https://bio.tools/clustergrammer SCR_015681 2026-02-14 02:02:51 41
oligo
 
Resource Report
Resource Website
1000+ mentions
oligo (RRID:SCR_015729) data processing software, data analysis software, source code, software application, software resource Software package to analyze oligonucleotide arrays (expression/SNP/tiling/exon) at probe-level. It currently supports Affymetrix (CEL files) and NimbleGen arrays (XYS files). oligonucleotide, microarray gene expression, r, oligonucleotide array, snp, gene expression, probe-level, affymetrix array, cel file, and nimblegen array, xys file, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
CAPES (Coordenação de Aprimoramento Pessoal de Nível Superior) ;
NCRR R01RR021967;
NHGRI P41HG004059
PMID:20688976 Free, Available for download, Runs on Mac OS, Runs on Windows biotools:oligo https://bio.tools/oligo SCR_015729 oligo package 2026-02-14 02:03:08 1749
BSVF
 
Resource Report
Resource Website
1+ mentions
BSVF (RRID:SCR_015727) BSVF sequence analysis software, data processing software, data analysis software, source code, software application, software resource Software code for bisulfite sequencing virus integration. This finder is for directional libraries only and does not support PBAT and indirectional libraries. virus integration, sequencing analysis, virus assembly, integration, bisulfite, bio.tools is listed by: bio.tools
is listed by: Debian
Open source biotools:bs-virus-finder https://bio.tools/bs-virus-finder SCR_015727 BSVF: Bisulfite Sequencing Virus integration Finder, Bisulfite Sequencing Virus integration Finder 2026-02-14 02:02:53 1
GenePattern Notebook
 
Resource Report
Resource Website
1+ mentions
GenePattern Notebook (RRID:SCR_015699) web application, software application, systems interoperability software, software resource, electronic laboratory notebook Interactive analysis notebook environment that streamlines genomics research by interleaving text, multimedia, and executable code into unified, sharable, reproducible “research narratives.” It integrates the dynamic capabilities of notebook systems with an investigator-focused, simple interface that provides access to hundreds of genomic tools without the need to write code. gene, genomics research, research narrative, notebook system, analysis notebook, bio.tools is listed by: bio.tools
is listed by: Debian
is affiliated with: GenePattern
NIGMS R01-GM074024;
NCI U24-CA194107
PMID:28822753 Open Source, Free, Available for download, Account required biotools:GenePattern_notebook https://bio.tools/GenePattern_notebook SCR_015699 GenePattern Notebook environment 2026-02-14 02:02:53 3
DISEASES
 
Resource Report
Resource Website
500+ mentions
DISEASES (RRID:SCR_015664) data or information resource, database Database that integrates evidence on disease-gene associations from automatic text mining, manually curated literature, cancer mutation data, and genome-wide association studies. It also assigns confidence scores that facilitate comparison of the different types and sources of evidence. disease, gene, disease-gene association, text-mining, , bio.tools, FASEB list is listed by: Debian
is listed by: bio.tools
Novo Nordisk Foundation Center for Protein Research NNF14CC0001;
European Union Seventh Framework Programme n259348
PMID:25484339 biotools:diseases https://bio.tools/diseases SCR_015664 2026-02-14 02:02:52 627
TISSUES
 
Resource Report
Resource Website
10+ mentions
TISSUES (RRID:SCR_015665) data or information resource, software resource, database, web application Database that integrates evidence on tissue expression from manually curated literature, proteomics and transcriptomics screens, and automatic text mining. It maps all evidence to common protein identifiers and Brenda Tissue Ontology terms, and further unifies it by assigning confidence scores that facilitate comparison of the different types and sources of evidence. tissue expression, proteomic, transcriptomic, text-mining, brenda tissue ontology, protein identifier, bio.tools uses: BRENDA Tissue and Enzyme Source Ontology
is listed by: Debian
is listed by: bio.tools
Novo Nordisk Foundation NNF14CC0001;
NCI U54 CA189205-01;
CSIRO’s OCE Science Leader program
PMID:26157623 Freely available, Free, Available for download biotools:tissues https://bio.tools/tissues SCR_015665 TISSUES: Tissue Expression Database, Tissue Expression Database 2026-02-14 02:03:07 42
HISAT2
 
Resource Report
Resource Website
10000+ mentions
HISAT2 (RRID:SCR_015530) sequence analysis software, data processing software, data analysis software, source code, software application, software resource Graph-based alignment of next generation sequencing reads to a population of genomes. alignment program, mapping reads, population genomics, human genome, bio.tools is used by: Fcirc
is listed by: Debian
is listed by: bio.tools
is related to: TopHat
has parent organization: Johns Hopkins University; Maryland; USA
is required by: SL-quant
is hosted by: GitHub
NLM R01-LM06845;
NIGMS R01-GM083873;
NSF CCF-0347992
PMID:25751142
DOI:10.1038/s41587-019-0201-4
Available for download OMICS_07225, biotools:hisat2 https://github.com/infphilo/hisat2
https://bio.tools/hisat2
https://sources.debian.org/src/hisat2/
SCR_015530 HISAT 2026-02-14 02:03:03 17595
Hybrid-denovo
 
Resource Report
Resource Website
1+ mentions
Hybrid-denovo (RRID:SCR_015866) sequence analysis software, data processing software, data analysis software, software application, software resource Software for a de novo OTU-picking pipeline integrating single- and paired-end 16S sequence tags. It is designed to take Illumina paired-end sequencing reads as input and output the OTU BIOM table, together with their representative sequences and a phylogenetic tree of OTUs. hybrid-denovo, 16S rRNA, microbiota pipeline, single-end, paired-end, illumina read, de novo, otu-picking pipeline, phylogenetic tree, python, bio.tools is listed by: bio.tools
is listed by: Debian
biotools:hybrid-denovo https://bio.tools/hybrid-denovo SCR_015866 2026-02-14 02:03:09 3

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