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https://keck.usc.edu/liver-diseases-research-center/about-the-center/scientific-cores/

Core facility which provides primary hepatocytes cultures of normal and diseased mice and rats and various cell lines to investigators. The cell separation subcore plays a role in translational research in DILI and alcoholic hepatitis, supporting funded studies of the role of innate and adaptive immune systems in elucidating pathophysiology, identifying biomarkers, and predicting response to treatments.

Proper citation: USC Liver Transplant Program and Center for Liver Disease Cell Separation and Culture Core (RRID:SCR_015233) Copy   

•   Source: SciCrunch Registry

http://cure.med.ucla.edu/cores/administrative

Management core that develops mission, goals, and strategies relating to the functioning of the CURE:DDRCC.

Proper citation: CURE - Digestive Diseases Research Center Administrative Core (RRID:SCR_015231) Copy   

•   Source: SciCrunch Registry

https://keck.usc.edu/liver-diseases-research-center/about-the-center/scientific-cores/

Core that maintains and provides access and training in the use of a large base of major and expensive equipment, including thermocyclers, plate readers, centrifuges, a wide range of customized HPLC services, and Seahorse metabolic applications.

Proper citation: USC Liver Transplant Program and Center for Liver Disease Analytical Metabolic Instrumentation Core (RRID:SCR_015232) Copy   

•   Source: SciCrunch Registry

http://www.massgeneral.org/csibd/cores/genetic.aspx

Core whose services include breeding and maintenance of mutant mouse stocks, characterization of murine models, bone marrow transfers and adoptive T cell transfers, in vivo tracking of fluorescently labeled bacteria and cells, and whole body imaging of bioluminescent and fluorescent signals.

Proper citation: Center for the Study of Inflammatory Bowel Disease Genetic Animal Models Core (RRID:SCR_015238) Copy   

•   Source: SciCrunch Registry

https://cdtr.wustl.edu/our-cores/administrative-core/

Management core whose main functions include organizing and managing membership committees, coordinating communication with the NIH and other research bases, and overseeing the use of funds.

Proper citation: Washington University Center for Diabetes Translation Research Administrative Core in Diabetes Research Core (RRID:SCR_015235) Copy   

•   Source: SciCrunch Registry

https://keck.usc.edu/liver-diseases-research-center/about-the-center/scientific-cores/

Core that provides standard and customized slide preparation, liver histochemistry and immunohistochemistry as well as laser-capture microscopy.

Proper citation: USC Liver Transplant Program and Center for Liver Disease Liver Histology Core (RRID:SCR_015236) Copy   

•   Source: SciCrunch Registry

http://www.kidneycenter.pitt.edu/cores/model_organisms.html

Core that uses the yeast S. cerevisiae and the zebrafish D. rerio to dissect fundamental aspects of kidney development and protein structure and function.

Proper citation: Pittsburgh Center for Kidney Research Model Organisms (RRID:SCR_015288) Copy   

•   Source: SciCrunch Registry

http://www.kidneycenter.pitt.edu/cores/imaging_core.html

Core that provides qualitative and quantitative image analysis of the kidney and lower urinary tract through performing light and electron microscopic analysis of epithelial cells and tissues, quantifying and reconstructing kidney and lower urinary tract-associated tissues and organs in 3D, and visualizing and quantifying molecular and cellular dynamics in living animals.

Proper citation: Pittsburgh Center for Kidney Research Kidney Imaging (RRID:SCR_015289) Copy   

•   Source: SciCrunch Registry

https://www.uab.edu/medicine/obriencenter/cores/clinical-studies-of-aki-core

Core facility which provides investigators access to patients with AKI through an established international network of collaborating investigators. It also provides core resources to support the design and conduct of clinical research in AKI and genomics resources to perform systematic genomic analyses and allow correlation with clinical phenotypic information.

Proper citation: UAB-UCSD Core Center for Acute Kidney Injury Research Clinical Studies of AKI (RRID:SCR_015287) Copy   

•   Source: SciCrunch Registry

http://sharedresources.fredhutch.org/core-facilities/comparative-medicine

THIS RESOURCE IS NO LONGER IN SERVICE.Documented on July 27,2022. Core facility that provides a variety of animal housing, veterinary and research support services.

Proper citation: Fred Hutchinson Cancer Research Center Co-operative Center for Excellence in Hematology Comparative Medicine (RRID:SCR_015326) Copy   

•   Source: SciCrunch Registry

http://medicine.iupui.edu/neph/obrien/biosensor

Core facility which develops, characterizes and validates fluorescence protein biosensors for intravital multiphoton microscopy.

Proper citation: Indiana O'Brien Center for Advanced Microscopic Analysis Biosensor Development Core (RRID:SCR_015281) Copy   

•   Source: SciCrunch Registry

http://www.kidneycenter.pitt.edu/cores/cell_physiology.html

Core that provides investigators with in vitro systems for the study of transport processes at the molecular, cell, and epithelial levels.

Proper citation: Pittsburgh Center for Kidney Research Cellular Physiology (RRID:SCR_015284) Copy   

•   Source: SciCrunch Registry

http://www.kidneycenter.pitt.edu/cores/single_nephron_core.html

Core that offers functional (in vitro microperfusion of isolated segments, measurements of transepithelial ion/solute fluxes, fluorescence functional imaging of single tubular cells), biochemical (microassays of enzyme/transporter activity), molecular (quantitation and analysis of RNA and protein), and analytical (targeted renal metabolomics of interrelated networks of small molecules) strategies applied to microdissected tubules, single cells, and urinary exosomes to address relevant questions proposed by users. It also provides analytical services for determining concentrations of exogenous pharmacological agents and molecular probes achieved within the tissue of interest.

Proper citation: Pittsburgh Center for Kidney Research Single Nephron and Metabolomics (RRID:SCR_015285) Copy   

•   Source: SciCrunch Registry

https://www.uab.edu/medicine/obriencenter/cores/biostatistics-core

Core provides statistical expertise in the conceptualization and design of projects, expertise in data management for the resulting clinical and bioinformatics data, and assistance with the preparation of project reports, presentations and manuscripts.

Proper citation: University of Alabama at Birmingham-University of California San Diego O'Brien Center for Acute Kidney Injury Research Biostatistical Core (RRID:SCR_015283) Copy   

•   Source: SciCrunch Registry

http://sharedresources.fredhutch.org/core-facilities/genomics

THIS RESOURCE IS NO LONGER IN SERVICE.Documented on July 27,2022. Core facility that provides expertise and support for generating genomics-based data. Services for DNA arrays, genetic analysis, and high-throughput screening are provided through three specialized laboratories.

Proper citation: Fred Hutchinson Cancer Research Center Co-operative Center for Excellence in Hematology Genomics Shared Resource (RRID:SCR_015327) Copy   

•   Source: SciCrunch Registry

http://obriencenter.yale.edu/mousecelllines.aspx

Core provides services to generate unique in vivo mouse models and kidney specific cell lines.

Proper citation: George M. O'Brien Kidney Center at Yale Mouse Genetics and Cell Line Core (RRID:SCR_015299) Copy   

•   Source: SciCrunch Registry

http://obriencenter.yale.edu/humangenetics.aspx

Core that provides infrastructure support for several key steps in translational research, including development of HIC protocols, patient recruitment, patient DNA extraction and archiving, tools for high throughput SNP genotyping and DNA sequencing, and analysis of genetic linkage and linkage disequilibrium.

Proper citation: George M. O'Brien Kidney Center at Yale Human Genetics and Clinical Research Core (RRID:SCR_015298) Copy   

•   Source: SciCrunch Registry

https://cdtr.wustl.edu/our-cores/solutions-to-diabetes-in-black-americans/

Core facility whose services include consultation about the challenges that Black Americans face regarding diet and food advertising, study design and implementation assistance, and positing relevant questions to the larger core for relevant research questions.

Proper citation: Washington University Center for Diabetes Translation Research Solutions to Diabetes in Black Americans Core (RRID:SCR_015215) Copy   

•   Source: SciCrunch Registry

http://cihd.cores.utah.edu/ironheme/

Core facility that provides analysis of metals, precursor porphyrins and heme for cell pellets, tissue, whole blood, urine, feces and other complex biological materials. It also provides measurements of activity of the enzymes responsible for heme biosynthesis for cell pellets, tissue and blood.

Proper citation: Center for Iron and Heme Disorders at the University of Utah Iron and Heme Core (RRID:SCR_015336) Copy   

•   Source: SciCrunch Registry

https://case.edu/medicine/cddrcc/cores/

Collection of four cores: the biorepository core, for clinical specimen storage; the Histology/Imaging Core, for tissue preparation and sectioning; the Mouse Models Core, for education and training on various mouse modeling techniques; and the Clinical Component of the Administrative Core, for clinical study design consultation.

Proper citation: Cleveland Digestive Diseases Research Core Facilities (RRID:SCR_015216) Copy   

•   Source: SciCrunch Registry