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https://www.uab.edu/medicine/cysticfibrosis/about/animal-core

Core that assists in mouse line generation by both oocyte micro-injection and by embryonic stem cell gene targeting technologies. It also establishes breeding colonies of cystic fibrosis mice, and genotypes and provides these to UAB investigators and furnishes electrophysiology tests of CFTR activation, including murine nasal potential difference assays and intestinal short circuit current measurements.

Proper citation: Gregory Fleming James Cystic Fibrosis Research Center Cystic Fibrosis Animal Models Core (RRID:SCR_015396) Copy   

•   Source: SciCrunch Registry

http://medicine.iupui.edu/neph/obrien/digital

Core facility which develops and implements software and methods of image segmentation for fluorescence microscopy data.

Proper citation: Indiana O'Brien Center for Advanced Microscopic Analysis Digital Image Analysis Core (RRID:SCR_015276) Copy   

•   Source: SciCrunch Registry

https://www.uab.edu/medicine/cysticfibrosis/about/cftr-expression-core

Core that maintains a repository of reagents for studying CFTR and assists with expression technologies using vaccinia, adenovirus and other methodologies and antibody based detection of cystic fibrosis related gene products.

Proper citation: Gregory Fleming James Cystic Fibrosis Research Center Cystic Fibrosis Transmembrane Conductance Regulator Expression Core (RRID:SCR_015397) Copy   

•   Source: SciCrunch Registry

http://www.uab.edu/medicine/hrfdcc/cores/d

Core goals include to develop in vitro predictive assays to identify and characterize HRFD lead compounds, develop in vivo predictive translational HRFD models to enhance efficacy assessment in preclinical testing, and develop advanced HRFD-specific toxicology and safety screens.

Proper citation: UAB Hepatorenal Fibrocystic Diseases Core Center Therapeutic Screening and Drug Development Resource (RRID:SCR_015314) Copy   

•   Source: SciCrunch Registry

http://medicine.iupui.edu/neph/obrien/probe

Core facility which develops and characterizes methods for expressing fluorescent biosensors in the rodent kidney to be paried with intravital microscopy.

Proper citation: Indiana O'Brien Center for Advanced Microscopic Analysis Probe Delivery Core (RRID:SCR_015274) Copy   

•   Source: SciCrunch Registry

http://www.dukekidneycenter.org/cores/clinical-and-translational-core

Core facility which investigates the connections between chronic kidney disease, cardiovascular disease, and hypertension. It focuses specifically on investigating the pathophysiology, epidemiology, and therapeutic response in on-going studies or existing datasets of one of the three diseases with the aim of relating data from individual diseases to each other.

Proper citation: Duke O'Brien Center for Kidney Research Clinical and Translational Core (RRID:SCR_015272) Copy   

•   Source: SciCrunch Registry

http://www.mmpc.org/shared/showCenterCore.aspx?id=30

Core that provides investigators with services to accurately measure the major components of energy balance in their mouse models and tests that allow investigators to examine physiological factors that may influence food intake or energy expenditure.

Proper citation: MMPC-University of California Davis Energy Balance Exercise and Behavior Core (RRID:SCR_015364) Copy   

•   Source: SciCrunch Registry

http://www.umassmed.edu/umpc/cores/metabolism/

Core that conducts specialized and non-invasive metabolic experiments to measure insulin sensitivity, glucose/lipid/protein metabolism, pancreatic beta-cell function, body composition and energy balance. Its services include access to hyperglycemic clamps to assess insulin secretion and pancreatic beta cell function in awake mice and exercise studiesl with acute, chronic endurance, and exhaustive exercise protocols and using in-house cage wheels.

Proper citation: MMPC-University of Massachusetts Medical School Metabolism Core (RRID:SCR_015369) Copy   

•   Source: SciCrunch Registry

http://www.mmpc.org/shared/showCenterCore.aspx?id=37

Core that offers measurement of gut permeability, plasma lipopolysaccharide binding protein (LBP) assay, and inflammatory profiling.

Proper citation: MMPC-University of California Davis Microbiome and Host Response Core (RRID:SCR_015361) Copy   

•   Source: SciCrunch Registry

http://www.mmpc.org/shared/showCenterCore.aspx?id=48

Core which provides a complete range of microvascular phenotyping of murine models of diabetes, obesity and metabolic disease, including validated, reproducible and standardized phenotyping of the three major microvascular complications: diabetic polyneuropathy, nephropathy and retinopathy.

Proper citation: MMPC-University of Michigan Medical School Microvascular Complications Core (RRID:SCR_015376) Copy   

•   Source: SciCrunch Registry

https://labnodes.vanderbilt.edu/resource/view/id/10810/community_id/1418

Core whose services include determining the components of energy balance with high precision and time resolution, providing robust imaging technology to monitor the dynamics of cellular process, and providing innovative mouse bariatric surgery models with application to basic and translational research.

Proper citation: MMPC-Vanderbilt University School of Medicine Metabolic Regulation Core (RRID:SCR_015377) Copy   

•   Source: SciCrunch Registry

http://umassmed.edu/umpc/animal/humanized-mouse-core/

Core which provides humanized mice that enable clinically relevant in vivo studies of human cells, tissues, and immune system without putting patients at risk and expert in vivo functional analysis of transplanted human islets and stem cell-derived b-cells in immunodeficient mice that are highly valuable to the mouse research community.

Proper citation: MMPC-University of Massachusetts Medical School Humanized Mouse Cell Transplantation and Assessment Core (RRID:SCR_015372) Copy   

•   Source: SciCrunch Registry

http://umassmed.edu/umpc/cores/islet-core/

Core which provides comprehensive in vivo, ex vivo, and in vitro analysis of pancreatic function and islet structure. Its services include mouse pancreas preparation for histological experiments, surgical isolation of mouse islets, and islet structural analysis.

Proper citation: MMPC-University of Massachusetts Medical School Islet Core (RRID:SCR_015370) Copy   

•   Source: SciCrunch Registry

http://www.med.unc.edu/cgibd/cores/biostatistics

Core facility that provides comprehensive statistical and data management services. Its statistical analysis services include study design, power and sample size analysis, randomization, statistical programming, consultation and the development of analysis plans, graphs, figures and reports.

Proper citation: University of North Carolina Center for Gastrointestinal Biology and Disease Biostatistics and Data Management Core (RRID:SCR_015616) Copy   

•   Source: SciCrunch Registry

http://www.med.unc.edu/cgibd/cores/histology

Core facility that provides a full range of histology services, encompassing routine and specialized grossing, tissue processing, paraffin embedding, microtomy, H&E and special staining, and immunohistochemistry. It also offers image analysis and consultations to CGIBD members and non-members.

Proper citation: University of North Carolina Center for Gastrointestinal Biology and Disease Histology Core (RRID:SCR_015614) Copy   

•   Source: SciCrunch Registry

http://www.med.upenn.edu/molecular/core_morphology.shtml

Core facility that provides histological services, equipment usage, and technical expertise to digestive and liver research projects.

Proper citation: University of Pennsylvania Center for Molecular Studies in Digestive and Liver Diseases Molecular Pathology and Imaging Core (RRID:SCR_015618) Copy   

•   Source: SciCrunch Registry

http://sph.unc.edu/norc/animal/

Core that offers technical support and expertise for measuring traits related to metabolism in mouse models of obesity and nutritionally relevant disease. It provides access to methods, equipment, and populations to support high quality and high throughput phenotyping of energy balance components in mice.

Proper citation: University of North Carolina at Chapel Hill Nutrition and Obesity Research Center Animal Metabolism Phenotyping Core (RRID:SCR_015465) Copy   

•   Source: SciCrunch Registry

http://depts.washington.edu/uwnorc/core-facilities/energy-balance-core/

Core that provides affiliated investigators with a resource for measuring energy balance and body composition in rodent models, and for applying neuroscience techniques to nutrition and obesity-related research.

Proper citation: University of Washington Nutrition and Obesity Research Center Energy Balance Core (RRID:SCR_015469) Copy   

•   Source: SciCrunch Registry

http://www.norc.uab.edu/corefacilities/animalmodels

Core that provides specialized expertise in the use of animal models and instrumentation to facilitate animal research related to nutrition and obesity.

Proper citation: University of Alabama at Birmingham Nutrition and Obesity Research Center Animal Models Core (RRID:SCR_015466) Copy   

•   Source: SciCrunch Registry

http://www.med.upenn.edu/molecular/core_molecular.shtml

Core facility that provides services that will enhance the analysis of both host and microbial biological processes as well as facilitate translation into the clinical arena via human subject research.

Proper citation: University of Pennsylvania Center for Molecular Studies in Digestive and Liver Diseases Host-Microbial Analytic and Repository Core (RRID:SCR_015620) Copy   

•   Source: SciCrunch Registry