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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://www.montclair.edu/mmrl/
Interdisciplinary research, teaching and service facility equipped with scanning and transmission electron microscopes, an atomic force microscope, and the ancillary instruments. Provides microscopic imaging, X-ray analysis, and specimen preparation services for biological, pharmaceutical, and materials scientific research. The MMRL consist of four individual microscope rooms, the Histology laboratory, and sample preparation and chemical storage areas.Graduate- and upper-undergraduate-level training is offered in the operation of electron microscopes, sample preparation, and thick/thin sectioning. Currently, MMRL houses transmission electron, scanning electron microscopes, and atomic force microscope. The microscopes available for use include: - Hitachi H-7500 transmission electron microscope - Hitachi S-3400N variable pressure scanning electron microscope with x-ray analysis and digital imaging - Hitachi S-2460N scanning electron microscope with x-ray analysis In addition, the following items are also available for MMRL users: - Three Leica 2030 rotary paraffin microtome - Two LKB ultramicrotomes - A LKB 7800 glass knife maker - Leica Reichert Ultratrim - Denton critical point dryer - Denton sputter coaters (Desk II and Desk IV) - Denton Vacuum evaporators (DV-502A) - Liquid nitrogen dewars (various sizes) - A Leica stereo dissecting microscope - A Tissue-TeK VIP Tissue Processor - A Tissue-TeK II Embedding Center
Proper citation: Montclair University Microscopy and Microanalysis Research Laboratory Core Facility (RRID:SCR_012453) Copy
http://www.scienceexchange.com/facilities/igsp-genome-sequencing-analysis-core-duke
The mission of the Genome Sequencing & Analysis Core Resource is to promote advance in biology by providing to researchers complete genomic solutions with the latest and most complementary technologies readily available. We provide services for traditional capillary sequencing, high-throughput next-generation sequencing, and various data analyses, both across Duke University campus and across the world. We offer services on seven sequencers at the moment.
Proper citation: Duke IGSP Genome Sequencing and Analysis Core (RRID:SCR_012331) Copy
http://www.scienceexchange.com/facilities/host-microbe-systems-biology-core-uc-davis
The UC Davis Host-Microbe Systems Biology Core offers NGS analytical services which will utilize state-of-the-art open source software platforms and other customized scripts developed by the HMSB Core co-Director Jonathan Eisen, Ph.D. The HMSB Core is designed to provide researchers with easily accessible, customized, and cost-effective resources for integrating analyses of microbial community structure and host-microbe interactions in health and disease.
Proper citation: UC Davis Host-Microbe Systems Biology Core (RRID:SCR_012334) Copy
https://moffitt.org/research-science/shared-resources/molecular-genomics/
Molecular Genomics Core Facility at Moffitt Cancer Center in Tampa, FL offers services to assess gene expression, epigenetic modification and sequence variation. Performs bulk and single cell RNA and DNA sequencing on Illumina platform, NanoString nCounter, GeneChip and Illumina array services.Offers services to discuss your project and timeline for your project.
Proper citation: Moffitt Cancer Center Molecular Genomics Core Facility (RRID:SCR_012333) Copy
http://www.scienceexchange.com/facilities/ucla-nanoelectronics-research-facility
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 19,2024. Core facility
Proper citation: UCLA Nanoelectronics Research Facility (RRID:SCR_012337) Copy
https://core.uconn.edu/resources/flowcytometry
Provides investigators with access to sophisticated instruments designed to detect and measure fluorescent light emission. Flow cytometers distinguish cells or particles based on size, internal complexity, and fluorescent signals. Cells or particles can also be sorted to obtain pure populations for further analysis or subsequent culture. Available imaging techniques include widefield, laser scanning confocal, spinning disk confocal, TIRF, and multiphoton confocal microscopy.
Proper citation: Connecticut University Flow Cytometry Core Facility (RRID:SCR_012341) Copy
http://www.scienceexchange.com/facilities/microcalorimetry-facility
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 22,2024. Microcalorimetry Facility was established in 2011 as the result of the acquisition of nano-ITC (Isothermal Titration) and nano-DSC (Differential Scanning) Calorimeters from TA Instruments, which was made possible with funding awarded through the VPR''s Major Equipment Competition in October 2010.
Proper citation: UConn Microcalorimetry Facility (RRID:SCR_012345) Copy
http://www.scienceexchange.com/facilities/high-throughput-screening-facility
The University of Connecticut High-Throughput Screening Facility (HTS Facility) was established in 2011 with funding awarded through the University''s Major Equipment Competition. Over the last 20 years, high-throughput screening has become an integral tool utilized by both pharmaceutical industry and academic institutions to identify new lead compounds for drug development. The HTS Facility is comprised of integrated instrumentation dedicated to aiding researchers in the small molecule screening and drug discovery process.
Proper citation: UConn High-Throughput Screening Facility (RRID:SCR_012344) Copy
http://www.scienceexchange.com/facilities/microscopy-core
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 22, 2024. Core facility
Proper citation: MGH Microscopy Core (RRID:SCR_012426) Copy
https://cancer.psu.edu/research/cores/organic-synthesis
Core to advance scientific impact of Penn State Cancer Institute investigators by synthesizing and providing chemical agents that are either not commercially available or cost-prohibitive, to facilitate ongoing cancer research. Assists in efforts towards discovering novel agents for treatment and prevention of cancer. Supports activities of development and synthesis of anticancer agents, chemical carcinogens, their detoxification products, reactive species of metabolic activation and DNA adducts formed with such species. Services also include identification and synthesis of biomarkers of uptake and activation of environmental carcinogens that require deuterated, tritiated, and 14C-labeled isotopes.
Proper citation: Penn State Cancer Institute Organic Synthesis Core Facility (RRID:SCR_012425) Copy
http://pctriadd.com/genomic-analysis/overview
Core offers sequencing and microarray services, solutions for the profiling of FFPE tissues, and complete, project-tailored downstream bioinformatics analysis. The core's structure enables the management of research projects from experimental design to analysis and interpretation of data as well as support for grant applications and publications. The LAGA provides open fee-for-service access as a core facility (intra-institutional services to its researchers) and as regional, national and international facility (inter-institutional services).
Proper citation: Vancouver Prostate Centre Laboratory for Advanced Genome Analysis (RRID:SCR_012394) Copy
http://www.scienceexchange.com/facilities/brain-imaging-center
The Henry H. Wheeler, Jr., Brain Imaging Center is one of four Technology Centers under the auspices of the Helen Wills Neuroscience Institute. It is a campus-wide resource that supports advanced brain imaging technologies dedicated solely to basic brain research.
Proper citation: UC Berkeley Brain Imaging Center (RRID:SCR_012398) Copy
https://www.utsouthwestern.edu/research/core-facilities/genomics/
Core provides access to next generation sequencing (NGS) to investigators at UT Southwestern, at other institutions in the UT System, and at additional cost to investigators outside of the UT system. Core can receive flow cell ready samples (sequencing libraries that are prepared by the user) or perform sequencing library production for genomic libraries, RNA-SEQ applications, and small RNA (microRNA) applications. Data output routinely will provide de-multiplexing and alignment to the genome of choice using a variety of assembly and analysis programs, including CLC-Biosystems workbench, a BWA-GATK-Genotyper pipeline, a BowTie-Top Hat analysis pathway, and the Illumina ELAND DNA sequence aligner. Limited access to post sequence data analysis software is also available through the core, including both CLC-Biosystems (2 floating licenses available for on campus users) and the Genome Studio software packages.
Proper citation: University of Texas Southwestern Genomics and Microarray Core (RRID:SCR_012431) Copy
http://www.scienceexchange.com/facilities/histology-core-facility-at-lake-nona
The Histology Core at Lake Nona is a full-service shared resource facility that provides histological services to Sanford-Burnham researchers and investigators throughout the scientific community. The Core offers technical support, consultative, and interpretive pathology to all investigators. Tissue samples are processed with the highest industry quality standards, using state-of-the-art instrumentation. The Core also assists with experiment design as well as the development and interpretation of tests and their results. Sanford-Burnham''''s Histology Core at Lake Nona is committed to collaborating with investigators and advancing research by carrying out critical tissue specimen validation and evaluation. Equipment and Resources: - Thermo Excelsior ES Tissue Processor - Thermo Histocentre_������������������������ 3 Embedding Unit - Thermo Cytospin 4 - Thermo Microm HM355S Microtome - Thermo Printmate 450 Cassette Printer - Thermo Microm HM550 Cryostat - Thermo Microm HM650 V Vibratome with cooling unit - Thermo Microm HM450 Sliding Microtome with freezing unit - Leica IP S Slide Printer - Leica RM2235 Microtome - Leica 1900UV Cryostat - Nikon Eclipse 80i Microscope with AR Elements imaging software - Ventana Discovery XT - Tissue-Tek?? Prisma Automated Slide Stainer and Glas_������������������������ g2 Coverslipper - Aperio ScanScope XT-Brightfield - Aperio ScanScope FL-Fluorescence
Proper citation: Sanford-Burnham Histology Core Facility at Lake Nona (RRID:SCR_012438) Copy
https://hddc.hms.harvard.edu/gnotobiotics-microbiology-and-metagenomics
Core facility that assists investigators evaluating host microbiota and its role in normal physiology and disease. It includes a number of resources for groups studying the role of the microbiota in human health and disease.
Proper citation: Harvard Digestive Diseases Center Biomedical CORE D: Gnotobiotic Mice, Microbiology and Metagenomics (RRID:SCR_012319) Copy
https://ragon.partners.org/musiebiostats/
Biostatistics core serves the needs of the HIV/AIDS researchers within the Ragon Institute and its affiliates at Harvard, MGH, MIT and University of Kwazulu Natal, South Africa. Provides expertise in planning, conduct and analysis of research with goal of enhancing scientific quality of HIV-related research at the institute. Primary objective is to ensure that studies are well designed, correctly analyzed, clearly presented, and correctly interpreted.
Proper citation: Massachusetts General Hospital Ragon Institute Biostatistics Core Facility (RRID:SCR_012323) Copy
http://www.scienceexchange.com/facilities/histopathology-core
Both animal model and clinical research require the production of high quality tissue samples for morphological and molecular analyses. The NYU Histopathology Core, one component of the Experimental Pathology Shared Resources provides?_services, instrumentation and training to facilitate the generation of these critical materials. Services offered by the Histopathology Core include: tissue preparation, processing, embedding, sectioning, histochemical staining, digital whole slide scanning, and laser capture microdissection of both animal and fixed human tissues. The Histopathology Core also makes available several instruments for investigator use on a self-serve basis. This option is valuable for researchers who wish to direct certain stages of specimen preparation and is more cost-effective in some cases. Available instrumentation includes a state-of the-art Laser Dissection Microscope, a microtome, a cryostat and a microscope fitted with a digital camera. Training is provided by Core staff. The components of pricing for each service include the cost of consumables, the cost for technician time for each service, and a small percentage of any associated service contracts. As with many of our services, the incremental cost of each procedure is affected by overall volume; as volume increases, we pass the resulting savings on to users in the form of reduced prices.
Proper citation: NYU Histopathology Core (RRID:SCR_012409) Copy
https://www.moffitt.org/research-science/shared-resources/small-animal-imaging-lab/
Core provides advanced and affordable multi-modality imaging services including consultation, imaging and image analysis for both basic and translational research. Offers instrumentation including 7T MRI, multimodal PET/SPECT/CT, ultrasound and optical modalities. Used to evaluate tumor development, progression, metastasis and therapy response in rodent models of cancer including development of imaging biomarkers, contrast agents and tumor targeting agents, evaluating tumor metabolism and microenvironment, and high-resolution anatomical imaging of human specimens.
Proper citation: Moffitt Cancer Center Small Animal Imaging Laboratory Core Facility (RRID:SCR_012401) Copy
An Core facility
Proper citation: MSU Skobeltsyn Institute of Nuclear Physics Laboratory of Ion Beam Nanotechnologies (RRID:SCR_012372) Copy
Provides tools and assistance to identify and monitor behavior in rodents. Supports basic and translational research by providing assistance with project development, technical assistance to identify and monitor behavior in rats and mice, training in techniques for analysis of animal behaviors, assisting with interpretation and presentation of data and results relating to animal behaviors.
Proper citation: University of Mississippi Medical Center Animal Behavior Core Facility (RRID:SCR_012494) Copy
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