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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
refgenie
 
Resource Report
Resource Website
1+ mentions
refgenie (RRID:SCR_017574) data management software, software application, software resource, service resource Software tool to organize, retrieve, and share genome analysis resources. Reference genome assembly asset manager. In addition to genome indexes, can manage any files related to reference genomes, including sequences and annotation files. Includes command line interface and server application that provides RESTful API, so it is useful for both tool development and analysis. Organize, retrive, share, genome, analysis, reference, assembly, asset, manager, sequence, annotation, file, command, line, interface, bio.tools is listed by: Debian
is listed by: bio.tools
DOI:10.1101/698704 Free, Available for download, Freely available biotools:Refgenie https://bio.tools/Refgenie SCR_017574 reference genome manager 2026-02-17 10:03:15 6
SpydrPick
 
Resource Report
Resource Website
1+ mentions
SpydrPick (RRID:SCR_018176) data analysis software, software application, data processing software, software resource Software command line tool for performing direct coupling analysis of aligned categorical datasets. Used for analysis at scale of pan genomes of many bacteria. Incorporates correction for population structure, which adjusts for phylogenetic signal in data without requiring explicit phylogenetic tree. Direct coupling analysis, aligned categorical datasets, analysis, genome, bacteria, phylogenetic signal, correction, phylogenetic tree, data, bio.tools is listed by: Debian
is listed by: bio.tools
COIN Center of Excellence ;
Academy of Finland ;
Wellcome Trust ;
European Research Council
PMID:31361894 Free, Available for download, Freely available biotools:SpydrPick https://anaconda.org/bioconda/spydrpick
https://bio.tools/SpydrPick
SCR_018176 2026-02-17 10:03:43 2
SuperDCA
 
Resource Report
Resource Website
1+ mentions
SuperDCA (RRID:SCR_018175) data analysis software, software application, data processing software, software resource Software tool for global direct coupling analysis of input genome alignments. Implements variant of pseudolikelihood maximization direct coupling analysis, with emphasis on optimizations that enable its use on genome scale. May be used to discover co evolving pairs of loci.Used for genome wide epistasis analysis. Protein, sequence, alignment, analysis, genome, loci, epistasis Academy of Finland ;
Wellcome Trust ;
Royal Society ;
European Research Council
PMID:29813016 Free, Available for download, Freely available SCR_018175 Super Direct Coupling Analysis 2026-02-17 10:03:02 1
TCGAbiolinks
 
Resource Report
Resource Website
50+ mentions
TCGAbiolinks (RRID:SCR_017683) data analysis software, software application, data processing software, software resource Software R Bioconductor package for integrative analysis with TCGA data.TCGAbiolinks is able to access National Cancer Institute Genomic Data Commons thorough its GDC Application Programming Interface to search, download and prepare relevant data for analysis in R. Integrative, analysis, TCGA data, cancer, genome, atlas, genomic, analysis, expression, methylated, region, survival plot, phenotype, tumor, epigenomic, alteration, clinical, molecular, retrival BridgeIRIS ;
INNOVIRIS ;
Region de Bruxelles Capitale ;
Brussels ;
Belgium ;
GENGISCAN ;
São Paulo Research Foundation
PMID:26704973
DOI:10.12688/f1000research.8923.2
Free, Available for download, Freely available https://github.com/BioinformaticsFMRP/TCGAbiolinks SCR_017683 Cancer Genome Atlas (TCGA) biolinks 2026-02-17 10:03:17 93
CRISPy-web
 
Resource Report
Resource Website
10+ mentions
CRISPy-web (RRID:SCR_017970) data access protocol, web service, software resource Web tool to design sgRNAs for CRISPR applications. Web tool based on CRISPy to design sgRNAs for any user-provided microbial genome. Implemented as standalone web application for Cas9 target prediction. Design, sgRNA, CRISP, microbial, genome, Cas9, target, prediction, data, guide, single, editing, bio.tools is listed by: bio.tools
is listed by: Debian
Novo Nordisk Foundation PMID:29062934 Free, Freely available biotools:crispy https://bio.tools/crispy SCR_017970 single guide RNA desing 2026-02-17 10:03:43 25
PAFScaff
 
Resource Report
Resource Website
1+ mentions
PAFScaff (RRID:SCR_017976) software application, data processing software, data analysis software, software resource, sequence analysis software Software as Pairwise mApping Format reference based Scaffold anchoring and super scaffolding tool. Dsigned for mapping genome assembly scaffolds to closely related chromosome level reference genome assembly. Pairwise, mapping, reference, scaffold, genomics, scaffolding, assembly, genome, chromosome, bio.tools is listed by: Debian
is listed by: bio.tools
Free, Freely available biotools:PAFScaff https://github.com/slimsuite/pafscaff/blob/master/PAFScaff.md
https://slimsuite.github.io/pafscaff/
https://bio.tools/PAFScaff
SCR_017976 Pairwise mApping Format reference-based Scaffold 2026-02-17 10:03:43 4
Codon Usage Analyzer
 
Resource Report
Resource Website
Codon Usage Analyzer (RRID:SCR_018500) Bio::CUA, Bio-CUA data analysis software, software application, data processing software, software resource Software tool as flexible and comprehensive codon usage analyzer. Used to analyze codon usage bias (CUB) and relevant problems. Codon usage analyzer, codon, codon usage bias, genome, gene, codon, sequence has parent organization: University of Rochester; New York; USA David and Lucile Packard Foundation ;
University of Rochester
DOI:10.1101/022814 Free, Freely available https://metacpan.org/release/Bio-CUA SCR_018500 2026-02-17 10:03:46 0
Human Gene Connectome Server
 
Resource Report
Resource Website
1+ mentions
Human Gene Connectome Server (RRID:SCR_002627) HGCS data analysis service, production service resource, analysis service resource, service resource An interactive web server that enables researchers to prioritize any list of genes by their biological proximity to defined core genes (i.e. genes that are known to be associated with the phenotype), and to predict novel gene pathways. gene, disease, phenotype, genome, connectome, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Human Gene Connectome
PMID:23509278 Free nlx_156049, biotools:hgcs https://bio.tools/hgcs SCR_002627 2026-02-17 09:59:55 5
Daring Nucleic Adventures - genegeek
 
Resource Report
Resource Website
Daring Nucleic Adventures - genegeek (RRID:SCR_005215) DNA, DNA - genegeek data or information resource, narrative resource, blog Hi. I''m genegeek (aka Catherine Anderson). I realized during my PostDoc that I preferred learning and explaining new results to doing science so I started a non-traditional career of teaching and outreach. I''ll be using this space to explore public perception of genetics and other cool molecular biology stuff. I hope to add to the great discussions re: new science discoveries and general understanding of genetics. I''ve been running an outreach program and enjoy talking to non-experts about their opinions and understanding. I hope my enthusiasm for the topics can come through the screen. My posts are presented as opinion and commentary and do not represent the views of LabSpaces Productions, LLC, my employer, or my educational institution. genetics, molecular biology, dna, science, genome, education is used by: NIF Data Federation
is used by: Integrated Blogs
has parent organization: LabSpaces
nlx_144219 SCR_005215 Daring Nucleic Adventures 2026-02-17 10:00:49 0
Computational Biology at ORNL
 
Resource Report
Resource Website
Computational Biology at ORNL (RRID:SCR_005710) Computational Biology at ORNL data analysis service, production service resource, analysis service resource, service resource We are the Computational Biology and Bioinformatics Group of the Biosciences Division of Oak Ridge National Laboratory. We conduct genetics research and system development in genomic sequencing, computational genome analysis, and computational protein structure analysis. We provide bioinformatics and analytic services and resources to collaborators, predict prospective gene and protein models for analysis, provide user services for the general community, including computer-annotated genomes in Genome Channel. Our collaborators include the Joint Genome Institute, ORNL''s Computer Science and Mathematics Division, the Tennessee Mouse Genome Consortium, the Joint Institute for Biological Sciences, and ORNL''s Genome Science and Technology Graduate Program. genetics, research, system development, genomic sequencing, computation, genome analysis, protein structure, analysis, gene, protein, gene annotation, annotation, genome has parent organization: Oak Ridge National Laboratory nlx_149161 SCR_005710 Computational Biology at Oak Ridge National Laboratory, Computational Biology and Bioinformatics Group at ORNL, Computational Biology Bioinformatics Group at ORNL 2026-02-17 10:00:56 0
GOtcha
 
Resource Report
Resource Website
1+ mentions
GOtcha (RRID:SCR_005790) GOtcha data analysis service, production service resource, analysis service resource, service resource GOtcha provides a prediction of a set of GO terms that can be associated with a given query sequence. Each term is scored independently and the scores calibrated against reference searches to give an accurate percentage likelihood of correctness. These results can be displayed graphically. Why is GOtcha different to what is already out there and why should you be using it? * GOtcha uses a method where it combines information from many search hits, up to and including E-values that are normally discarded. This gives much better sensitivity than other methods. * GOtcha provides a score for each individual term, not just the leaf term or branch. This allows the discrimination between confident assignments that one would find at a more general level and the more specific terms that one would have lower confidence in. * The scores GOtcha provides are calibrated to give a real estimate of correctness. This is expressed as a percentage, giving a result that non-experts are comfortable in interpreting. * GOtcha provides graphical output that gives an overview of the confidence in, or potential alternatives for, particular GO term assignments. The tool is currently web-based; contact David Martin for details of the standalone version. Platform: Online tool function, protein, prediction, genome, annotation, gene, statistical analysis is listed by: Gene Ontology Tools
is related to: Gene Ontology
has parent organization: University of Dundee; Scotland; United Kingdom
Wellcome Trust 060269;
European Union fifth framework QLRI-CT-2000-00127
PMID:15550167 Free for academic use nlx_149269 http://www.compbio.dundee.ac.uk/Software/GOtcha/gotcha.html SCR_005790 2026-02-17 10:01:00 1
Systems Transcriptional Activity Reconstruction
 
Resource Report
Resource Website
5000+ mentions
Systems Transcriptional Activity Reconstruction (RRID:SCR_005622) STAR data or information resource, database, service resource A next-generation web-based application that aims to provide an integrated solution for both visualization and analysis of deep-sequencing data, along with simple access to public datasets. genome browser, genome, next generation sequence, visualization, FASEB list is used by: CIRCexplorer
is listed by: OMICtools
is related to: star-for-criu
has parent organization: University of California at San Diego; California; USA
Account required, Or Guest login OMICS_00895 SCR_005622 Systems Transcriptional Activity Reconstruction Genome Browser, Systems Transcriptional Activity Reconstruction, STAR Genome Browser 2026-02-17 10:00:47 6475
LegumeIP
 
Resource Report
Resource Website
10+ mentions
LegumeIP (RRID:SCR_008906) LegumeIP data or information resource, production service resource, analysis service resource, database, service resource, data analysis service LegumeIP is an integrative database and bioinformatics platform for comparative genomics and transcriptomics to facilitate the study of gene function and genome evolution in legumes, and ultimately to generate molecular based breeding tools to improve quality of crop legumes. LegumeIP currently hosts large-scale genomics and transcriptomics data, including: * Genomic sequences of three model legumes, i.e. Medicago truncatula, Glycine max (soybean) and Lotus japonicus, including two reference plant species, Arabidopsis thaliana and Poplar trichocarpa, with the annotation based on UniProt TrEMBL, InterProScan, Gene Ontology and KEGG databases. LegumeIP covers a total 222,217 protein-coding gene sequences. * Large-scale gene expression data compiled from 104 array hybridizations from L. japonicas, 156 array hybridizations from M. truncatula gene atlas database, and 14 RNA-Seq-based gene expression profiles from G. max on different tissues including four common tissues: Nodule, Flower, Root and Leaf. * Systematic synteny analysis among M. truncatula, G. max, L. japonicus and A. thaliana. * Reconstruction of gene family and gene family-wide phylogenetic analysis across the five hosted species. LegumeIP features comprehensive search and visualization tools to enable the flexible query on gene annotation, gene family, synteny, relative abundance of gene expression. gene function, genome evolution, legume, gene, genome, plant, genomics, transcriptomic, gene annotation, gene family, synteny, gene expression, blast, genomic sequence, microarray, rna-seq, comparative genomics, bio.tools is listed by: 3DVC
is listed by: Debian
is listed by: bio.tools
is related to: UniProt
is related to: InterProScan
is related to: Gene Ontology
is related to: KEGG
has parent organization: Samuel Roberts Noble Foundation
Samuel Roberts Noble Foundation ;
NSF ABI-0960897
PMID:22110036 biotools:legumeip, nlx_151455 https://bio.tools/legumeip SCR_008906 LegumeIP: an integrative database for comparative genomics and transcriptomics of model legumes, LegumeIP - An Integrative Platform to Study Gene Function and Genome Evolution in Legumes 2026-02-17 10:01:19 19
BeeBase
 
Resource Report
Resource Website
50+ mentions
BeeBase (RRID:SCR_008966) BeeBase data or information resource, production service resource, analysis service resource, database, service resource, data analysis service, data set Gene sequences and genomes of Bombus terrestris, Bombus impatiens, Apis mellifera and three of its pathogens, that are discoverable and analyzed via genome browsers, blast search, and apollo annotation tool. The genomes of two additional species, Apis dorsata and A. florea are currently under analysis and will soon be incorporated.BeeBase is an archive and will not be updated. The most up-to-date bee genome data is now available through the navigation bar on the HGD Home page. genome, gene set, sequence, bee, genomics, entomology, blast, annotation, pest, pathogen, honey, beehive, insect, bee pollen, bee product, bee culture, pollination, pollinator, bio.tools, FASEB list is listed by: re3data.org
is listed by: Debian
is listed by: bio.tools
has parent organization: University of Missouri; Missouri; USA
Texas Agricultural Experiment Station ;
Golden Heritage Foods and Sioux Honey Association ;
NHGRI 5-P41-HG000739-13;
USDA 2008-35302-18804
PMID:21071397 Open unspecified license, Acknowledgement requested, Data Usage Policy nlx_152034, biotools:hgd, r3d100010925 https://bio.tools/hgd
https://doi.org/10.17616/R3Z629
SCR_008966 Hymenoptera Genome Database 2026-02-17 10:01:28 56
Renal Disease Portal
 
Resource Report
Resource Website
Renal Disease Portal (RRID:SCR_009030) Renal Disease Portal data or information resource, topical portal, disease-related portal, portal, data set An integrated resource for information on genes, QTLs and strains associated with a variety of kidney and renal system conditions such as Renal Hypertension, Polycystic Kidney Disease and Renal Insufficiency, as well as Kidney Neoplasms. gene, quantitative trait locus, strain, renal hypertension, kidney neoplasm, phenotype, pathway, biological process, disease, kidney, genome, gviewer, chromosome, molecular function, cellular component, visualization, synteny is related to: NIDDK Information Network (dkNET)
is related to: Gene Ontology
has parent organization: Rat Genome Database (RGD)
Renal disease, Renal hypertension, Polycystic kidney disease, Renal insufficiency, Kidney neoplasm, Diabetes Insipidus, Hyperoxaluria, Renal hypertension, Nephritis, Nephrocalcinosis, Nephrolithiasis, Nephrosis, Renal Fibrosis, Inborn Error of Renal Tubular Transport, Uremia nlx_153941 SCR_009030 RGD Renal Disease Portal 2026-02-17 10:01:28 0
TESS: Transcription Element Search System
 
Resource Report
Resource Website
100+ mentions
TESS: Transcription Element Search System (RRID:SCR_010739) TESS data or information resource, production service resource, analysis service resource, database, service resource, data analysis service TESS is a web tool for predicting transcription factor binding sites in DNA sequences. It can identify binding sites using site or consensus strings and positional weight matrices from the TRANSFAC, JASPAR, IMD, and our CBIL-GibbsMat database. You can use TESS to search a few of your own sequences or for user-defined CRMs genome-wide near genes throughout genomes of interest. Search for CRMs Genome-wide: TESS now has the ability to search whole genomes for user defined CRMs. Try a search in the AnGEL CRM Searches section of the navigation bar.. You can search for combinations of consensus site sequences and/or PWMs from TRANSFAC or JASPAR. Search DNA for Binding Sites: TESS also lets you search through your own sequence for TFBS. You can include your own site or consensus strings and/or weight matrices in the search. Use the Combined Search under ''Site Searches'' in the menu or use the box for a quick search. TESS assigns a TESS job number to all sequence search jobs. The job results are stored on our server for a period of time specified in the search submit form. During this time you may recall the search results using the form on this page. TESS can also email results to you as a tab-delimited file suitable for loading into a spreadsheet program. Query for Transcription Factor Info: TESS also has data browsing and querying capabilities to help you learn about the factors that were predicted to bind to your sequence. Use the Query TRANSFAC or Query Matrices links above or use the search interface provided from the home page. transcription factor, dna sequence, genome, promoter, gene regulation, FASEB list has parent organization: University of Pennsylvania; Philadelphia; USA PMID:18428685 nlx_97404 http://www.pcbi.upenn.edu/tess SCR_010739 Transcription Element Search System 2026-02-17 10:01:52 189
SNVrap
 
Resource Report
Resource Website
1+ mentions
SNVrap (RRID:SCR_010512) data access protocol, data or information resource, production service resource, analysis service resource, service resource, software resource, web service, data analysis service, data set The web portal provides comprehensive local database of human genome variants with a user-friendly web page that provides a one-stop annotating and funtonal prediction service which is both convenient and up-to-date. A query can be accepted as either a dbSNP Id or a chromosomal location and our system will instantly provide all the annotation information in an interactive LD panel. The system can also simultaneously prioritize this variant based on additive effect mode by corresponding annotation information and evaluate the variant effect that is then displayed in a prioritization tree. Furthermore, cohort sequencing continuously produces lots of un-annotated variants such as rare variants or de novo variants, and our system can even fit this data by accepting genomic coordinates (hg19) to offer maximal annotations. Main Functions Over 40 up-to-date annotation items for human single nucleotide variations; Functional prediction for different types of variants; Dynamic LD panel for both HapMap and 1000 Genomes Project populations; Prioritization score and tree viewer based on variant functional model. genetic variant, prioritize, genome, chromosome, functional prediction, transcription factor-binding site, mirna, mirna target site, prediction, target site, transcription factor, binding site, statistics, trait/disease-associated snp, single nucleotide polymorphism PMID:25308971 nlx_158733 http://jjwanglab.org/snvrap/snvrap/snvrap/quickrap SCR_010512 2026-02-17 10:01:54 4
JiffyNet
 
Resource Report
Resource Website
1+ mentions
JiffyNet (RRID:SCR_011954) software application, production service resource, analysis service resource, service resource, software resource, data analysis service, simulation software Web based instant protein network modeler for newly sequenced species. Web server designed to instantly construct genome scale protein networks using protein sequence data. Provides network visualization, analysis pages and solution for instant network modeling of newly sequenced species. protein network, protein, network, genome, sequence, pathway annotation, network visualization, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Yonsei University; Seoul; South Korea
National Research Foundation of Korea ;
Next-Generation BioGreen 21 Program
PMID:23685435 Free, Freely available OMICS_01548, biotools:jiffynet https://bio.tools/jiffynet SCR_011954 2026-02-17 10:02:06 1
BWA
 
Resource Report
Resource Website
1000+ mentions
BWA (RRID:SCR_010910) BWA alignment software, software application, data processing software, data analysis software, software resource, sequence analysis software, image analysis software Software for aligning sequencing reads against large reference genome. Consists of three algorithms: BWA-backtrack, BWA-SW and BWA-MEM. First for sequence reads up to 100bp, and other two for longer sequences ranged from 70bp to 1Mbp. sequence, alignment, reference, genome, human, short, long, read, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
is related to: shovill
is related to: Proovread
is related to: BWA-MEM2
has parent organization: SourceForge
is required by: RelocaTE
PMID:19451168
PMID:20080505
DOI:10.1093/bioinformatics/btp324
Free, Available for download, Freely available SCR_015853, biotools:bwa-sw, OMICS_00654 https://sourceforge.net/projects/bio-bwa/files/
https://bio.tools/bwa-sw
https://sources.debian.org/src/bwa/
SCR_010910 Burrows-Wheeler Aligner (BWA), Burrows-Wheeler Aligner 2026-02-17 10:01:53 2291
Phenotree
 
Resource Report
Resource Website
Phenotree (RRID:SCR_003591) Phenotree data or information resource, service resource, data set Web server to search for genes involved in given phenotypic difference between mammalian species. The mouse-referenced multiple alignment data files used to perform the forward genomics screen is also available. The webserver implements one strategy of a Forward Genomics approach aiming at matching phenotype to genotype. Forward genomics matches a given pattern of phenotypic differences between species to genomic differences using a genome-wide screen. In the implementation, the divergence of the coding region of genes in mammals is measured. Given an ancestral phenotypic trait that is lost in independent mammalian lineages, it is shown that searching for genes that are more diverged in all trait-loss species can discover genes that are involved in the given phenotype. gene, genotype, phenotype, alignment, trait, genome, alignment is related to: UCSC Genome Browser
has parent organization: Stanford University; Stanford; California
PMID:23022484 Acknowledgement requested, Non-commercial, Free for personal use, Http://stanford.edu/site/terms.html nlx_157736 SCR_003591 Forward Genomics - Phenotree server, Forward Genomics - Phenotree search 2026-02-17 10:00:14 0

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