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https://www.pennmedicine.org/departments-and-centers/department-of-radiology/radiology-research/core-facilities/cactis-lab

CACTIS mission is to oversee proposed research protocols that involve human, animal, phantom or specimen studies in an effort to achieve two goals, to ensure that all research performed on CT scanners comply with CACTIS and University policy, and Federal Regulations, and to determine if CACTIS can maintain the resources required to carry out each research protocol, including personnel, software, hardware and scan time. Additionally, CACTIS oversees the day-to-day operations of all CT procedures associated with research protocols, provides information regarding the use of CT facilities to the research community at the University of Pennsylvania, provides CACTIS users with all of the policies of the institution governing research, and ensures that CACTIS is in compliance with these policies. The service center strives to support the Perelman School of Medicine�s research endeavors by providing CT research services for a fee designed only to cover actual costs.

Proper citation: University of Pennsylvania Perelman School of Medicine Center for Advanced Computer Tomography Imaging Services Core Facility (RRID:SCR_022395) Copy   

•   Source: SciCrunch Registry

https://www.cceb.med.upenn.edu/bac

Provides wide range of biostatistical and epidemiological consulting services.

Proper citation: University of Pennsylvania Perelman School of Medicine Biostatistics Analysis Center Core Facility (RRID:SCR_022393) Copy   

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https://www.research.chop.edu/penn-acute-biobanking-core

Core encourages and facilitates microbiome focused research in pathogenesis, diagnosis and treatment of patients with critical illness. Core assists in research by providing de-identified samples with linked clinical metadata to support research in this area, collect specimens as needed in support of microbiome research, and offer support for development of such research in the critical care setting.

Proper citation: University of Pennsylvania Perelman School of Medicine Acute Care Biobanking Core Facility (RRID:SCR_022392) Copy   

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https://wiki.umontreal.ca/display/BiologieStructurale/Presentation+of+the+platform

Offers access to several scientific instruments intended to answer structural biological questions for scientific community.Consists of high field nuclear magnetic resonance spectrometers (500 MHz, 600 MHz with cryo-probe and 700 MHz) controlled with recent NEO consoles from Bruker, small angle X-rays scattering (SAXS) instrument, with high throughput robotics. SAXS can be coupled to liquid chromatography system for SEC-SAXS applications.Other instruments include size exclusion chromatography system coupled to multi angle light scattering detector (SEC-MALS), isothermal titration calorimetry (ITC) instrument as well as several liquid handling robots for rapid bio molecular crystal preparation and screening. Users have also access to bio-informatics room with several Linux computers for data analysis.Personnel is available and will teach and support users on instruments, research consultation and turn key services are also available upon request.

Proper citation: University of Montreal Structural Biology Platform Core Facility (RRID:SCR_022303) Copy   

•   Source: SciCrunch Registry

http://www.med.uvm.edu/flowcytometry/home

Harry Hood Bassett FCCS Facility is located in Given Medical Research Building Room C316-UVM. Facility provides flow cytometers and personnel provide scientific and technical consultation to faculty and staff in design of flow cytometric experiments, and assistance in data analysis and interpretation.

Proper citation: University of Vermont Larner College of Medicine Flow Cytometry and Cell Sorting Core Facility (RRID:SCR_022147) Copy   

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https://genetics.med.upenn.edu/cores/genomic-analysis-core/

Facility provides full service whole genome and targeted molecular profiling of DNA and RNA on multiple platforms. Core supports quantitative RNA profiling (gene expression) on Affymetrix GeneChips and high-throughput Gene Titan instruments, Fluidigm BioMark HD and, ABI QS 12K real-time PCR machine. DNA profiling (genotyping) is offered on Affymetrix SNP GeneChip and high-throughput Gene Titan instruments, Fluidigm BioMark HD and, ABI QS 12K. Agilent aCGH platform provides genome-wide chromosomal analysis.Users benefit from consultation and training available throughout their projects, including during experimental design and budget development, sample accrual, data management and analyses and, manuscript preparation.

Proper citation: University of Pennsylvania Perelman School of Medicine Penn Genomic Analysis Molecular Profiling Core Facility (RRID:SCR_022389) Copy   

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http://www.confocal.uct.ac.za/

Light and fluorescence microscopy core facility with focus on applications in infectious disease, pathogen and human health research.

Proper citation: University of Cape Town Institute of Infectious Disease and Molecular Medicine Confocal and Light Microscope Imaging Core Facility (RRID:SCR_022309) Copy   

•   Source: SciCrunch Registry

https://www.mines.edu/shared-facilities/project_category/nanofabrication/

Facility houses cleanrooms with processing equipment for making and characterizing electronic devices, thin film deposition tools for creation of metallic and ceramic thin film devices, and characterization lab with tools for surface, morphological, and optical characterization of materials.

Proper citation: Colorado School of Mines Shared Instrumentation Facility Surface Characterization and Thin Film Deposition Core Facility (RRID:SCR_022047) Copy   

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https://lsbi.chem.tamu.edu/

Facility housed in Department of Chemistry.Designed to be multi user laboratory supporting major research initiatives. Instruments are currently available on fee for use basis, and others may be made available on case by case considerations.

Proper citation: Texas A and M University Laboratory for Synthetic Biologic Interactions Core Facility (RRID:SCR_022287) Copy   

•   Source: SciCrunch Registry

https://histology.forsyth.org/

Core offers consulting and support services for both soft tissue and precise hard tissue analysis. Services include: tissue processing, embedding, sectioning, staining, and guidance on protocols. Can embed samples in standard molds or custom molds in paraffin, resin, or as frozen tissue for routine histology. Provides special stains and immunohistological studies.

Proper citation: Forsyth Institute Histology Core Facility (RRID:SCR_022165) Copy   

•   Source: SciCrunch Registry

https://calm.mcmaster.ca/

Provides access to light microscopy, photo-patterning, and light-assisted 3D printing techniques to help researchers in science, engineering and life sciences as well as our industrial partners achieve their scientific goals.

Proper citation: McMaster University Centre for Advanced Light Microscopy Core Facility (RRID:SCR_022312) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/carc/

Core provides services to users for performing precision, image guided radiotherapy with both Photons and Protons (including FLASH proton radiotherapy) on cells, rodents and larger animals. Physicists will provide expert dosimetry and treatment planning capabilities. Instrumentation consists of two image guided SARRP 200 Small Animal Radiation Research Platforms (Xstrahl) capable of irradiating rodent tissues from 1 mm-20 mm in diameter; research proton beamline (IBA, Roberts Proton Center); one X-RAD 320ix cabinet x-ray irradiator (Precision X-Ray); and two Cs gamma-ray irradiators (Shepherd Mark I), suitable for whole body radiation of rodents.

Proper citation: University of Pennsylvania Perelman School of Medicine Cell and Animal Radiation Core Facility (RRID:SCR_022377) Copy   

•   Source: SciCrunch Registry

https://www.jurado-lab.com/absl3

Facility offers procedural and animal housing to perform in vivo research with biosafety level 3 pathogens, such as SARS-CoV-2. Services include consultation, specialized training, and basic/advanced technical services. Provides equipment to longitudinally monitor mice over course of infection. Animal housing space includes three ABSL-3 separate housing cubicles with Allentown BCU-2 animal cages. Animals will be housed under pathogen free conditions at AAALAC accredited University Laboratory Animal Resources facilities within Vernon and Shirley Hill Pavilion using animal protocols approved by Institutional Animal Care and Use Committee.

Proper citation: University of Pennsylvania Perelman School of Medicine Animal Biosafety Level 3 Core Facility (RRID:SCR_022372) Copy   

•   Source: SciCrunch Registry

https://pathology.med.upenn.edu/research/centers-and-institutes/cooperative-human-tissue-network

Human tissue procurement service within Department of Pathology at HUP, that assists investigators with collection, processing and preservation of research samples. Our staff will personalize sample acquisition and processing to meet project requirements. Samples (malignant, normal, diseased, etc.) and biofluids can be preserved in a range of methods (fresh, frozen, fixed, etc.).

Proper citation: University of Pennsylvania Perelman School of Medicine Cooperative Human Tissue Network Core Facility (RRID:SCR_022407) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/cbica/cubic.html

Linux based High Performance Computing resource available to faculty conducting research related to medical imaging and informatics. There are over 150 compute nodes with more than 5000 Intel Xeon CPUs and 58TB of RAM, over 100 GPUs, and 600TB of storage in the cluster. Facility management structure is designed to encourage data sharing and use of common software on this powerful resource, particularly in development of new software and application of imaging to new domains.

Proper citation: University of Pennsylvania Perelman School of Medicine CUBIC (HPC Cluster) (RRID:SCR_022406) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/idom/drc/cores/ria.html

Core offers immunoassay, metabolite, and HPLC services to basic, translational, and clinical investigators performing diabetes and related metabolic disease research.RIA /Biomarkers Core is located on the 12th floor of Smilow Center for Translational Research.Approximately 100 different diabetes, obesity and metabolism-related biomarkers from multiple species including human can be assayed using radioimmunoassay (RIA), enzyme-linked immunosorbent assay (ELISA, both absorbance and fluorometric), multiplex ELISA on the Luminex platform, and enzymatic and HPLC methods for an expanding variety of diabetes and metabolism related metabolites, hormones, catecholamines and cytokines derived from blood, urine, and tissue samples.

Proper citation: University of Pennsylvania Perelman School of Medicine Radioimmunoassay and Biomarkers Core Facility (RRID:SCR_022405) Copy   

•   Source: SciCrunch Registry

https://www.itmat.upenn.edu/bmic/

Supports next generation infrastructure for clinical data storage and management, next generation analytics, next generation infrastructure for support of clinical research including new clinical trials management system and software, next generation infrastructure for centralizing and integrating external sources of data such as genomics data. Enables future clinical and translational research through biomedical informatics education and training targeted at graduate students, postdoctoral students, residents, fellows, as well as faculty across the biomedical research spectrum.

Proper citation: University of Pennsylvania Perelman School of Medicine Center for BioMedical Informatics Core Facility (RRID:SCR_022401) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/cpob/biostatistical-consulting.html

Service supports consultation and collaboration in areas of biostatistics and epidemiology to Penn vision scientists. Biostatisticians and data management experts provide advice on study design, and offer services in sample size determinations, data management, data analysis, data interpretation, and data presentation. They are active participants in the development and writing of grant applications and manuscripts.Consulting personnel are CPOB members. In addition to their methodological and technical expertise, consultants are knowledgeable about ocular conditions under study in Penn vision community, about commonly used measures that are unique to vision research (visual acuity, refractive error, visual field indices, etc) and specialized statistical analysis techniques required for many experimental designs used in vision research (correlated data techniques to handle appropriately data from two eyes of same subject). Majority of projects are patient oriented researchers,however, CPOB Consulting Service also works on data analysis with bench laboratory scientists.

Proper citation: University of Pennsylvania Perelman School of Medicine Center for Preventive Ophthalmology and Biostatistics Biostatistical Consulting Core Facility (RRID:SCR_022400) Copy   

•   Source: SciCrunch Registry

https://ibicic.med.upenn.edu/

Core assists faculty, staff, and students with conducting research projects using electronic health record data.Facilitates access to clinical data and performs data analysis using artificial intelligence, ontologies, natural language processing, machine learning, and visual analytics. Provides innovative research services by applying data science to clinical data in order to learn actionable healthcare knowledge and develop impactful solutions for improving patient care. Services include facilitating access to Penn Medicine clinical data resources, performing data analysis using diverse computational methods, and providing tools for exploratory data analysis/visualize with priority access to the IBI Idea Factory for immersive display of data and research results. �

Proper citation: University of Pennsylvania Perelman School of Medicine IBI Clinical Research Informatics Core Facility (RRID:SCR_022409) Copy   

•   Source: SciCrunch Registry

https://pathbio.med.upenn.edu/hic/site/

Core provides wet bench expertise and infrastructure support for early phase�clinical trials and other investigations. Offers purified cell subsets from healthy human apheresis donors. �HIC staff are qualified to�perform blood (PBMC)�and tissue processing for viable cryopreservation following validated�standard operating procedures. Offers�range of immunological assays including digital ELISA, ELISA, ELISPOT, Luminex, flow cytometry and immune repertoire profiling (NGS of BCR and TCR rearrangements in bulk and single cell formats).Offers investigators expertise and guidance in clinical trial sample processing, regulatory compliance, immunology assay design and validation, data analysis and grant writing support.

Proper citation: University of Pennsylvania Perelman School of Medicine Human Immunology Core Facility (RRID:SCR_022380) Copy   

•   Source: SciCrunch Registry