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http://www.facs.au.dk

Facility is equipped with cell sorters, analyzers, ImageStream and full spectrum flow cytometer. Staff provides training and maintenance.

Proper citation: Aarhus University Fluorescence Activated Cell Sorting Core Facility (RRID:SCR_022323) Copy   

•   Source: SciCrunch Registry

https://vpr.tamu.edu/core_facility/high-throughput-research-and-screening-center/

Core provides industry standard high throughput screening and automated microscopy capabilities to scientists performing drug discovery research. Provides access to automated infrastructure to support phenotypic and biochemical targets. Provides ready access to collections of current FDA approved drugs and clinical candidates exhibiting drug like qualities of acceptable solubility, desirable ADME/toxicology properties and adequate bioavailability. Has collections of mechanistically annotated informer sets that are pathway specific modulators for studying mechanism of action or target identification, collections of natural products and diverse sets of small molecules that can be interrogated for new target discovery. Each project is individually evaluated and team of scientists from CDDP is created to fit specific needs of project from assay design and development through primary, secondary and orthogonal screening.

Proper citation: Texas A and M University Institute of Biosciences and Technology High Throughput Research and Screening Center Combinatorial Drug Discovery Core Facility (RRID:SCR_022214) Copy   

•   Source: SciCrunch Registry

https://gtp.med.upenn.edu/core-laboratories-public/vector-core

Resource for investigators requiring viral vectors for preclinical studies and other basic research applications such as gene therapies for acquired and inherited diseases.Provides production of high quality vectors and distribution of improved vector technologies services.

Proper citation: University of Pennsylvania Perelman School of Medicine Vector Core Facility (RRID:SCR_022432) Copy   

•   Source: SciCrunch Registry

https://www.pennmedicine.org/departments-and-centers/department-of-radiology/radiology-research/labs-and-centers/quantitative/ultrasound-research-laboratory

Develops new ultrasound technologies and clinical applications, to bridge gap between technology and clinical applications, and to provide ultrasound imaging resources to other research. Consists of core group of scientists, sonographers and technicians with expertise in ultrasound technology and computer programming. This group works with clinicians in multiple specialties; including radiologists, cardiologists and surgeons. Core provides ultrasound scanner, sonographer and part-time radiologist on staff to conduct clinical and pre-clinical imaging.Helps with studies involving measurement of angiogenesis, vascularity, tissue elasticity, contrast agents, and effects of various physical and pharmaceutical agents on blood flow and tissue vascularity. Studies include research on cancer, cardiovascular disease and musculoskeletal disease.

Proper citation: University of Pennsylvania Perelman School of Medicine Ultrasound Research Laboratory Core Facility (RRID:SCR_022431) Copy   

•   Source: SciCrunch Registry

https://www.pennmedicine.org/departments-and-centers/department-of-radiology/radiology-research/core-facilities/pet-center

Dedicated to continuing advancement of molecular imaging and seeks to build network of collaborators to conduct translational research using existing and new radiotracers to help better understand the diagnosis, physiology and treatment of multiple diseases. Educates referring clinicians and their patients about emerging benefits of PET/CT diagnostic procedures, other radiotracer imaging methods and radionuclide therapies as tools in their research and clinical practice.Provides opportunities and mentoring for individuals interested in pursuing work or collaborations within molecular imaging field. Provides scanners as well as cyclotron facility.

Proper citation: University of Pennsylvania Perelman School of Medicine Positron Emission Tomography Center Core Facility (RRID:SCR_022429) Copy   

•   Source: SciCrunch Registry

https://www.itmat.upenn.edu/tbic.html

Mission is to act as portal for research community into Bio-medical imaging resources of University of Pennsylvania. Goals include creating and maintaining access for research community to Bio-medical imaging technologies, enabling research investigators to benefit from Bio-imaging expertise and experience, and educating researchers about Bio-medical imaging options through targeted seminars, research fellowships, and established training programs.

Proper citation: University of Pennsylvania Perelman School of Medicine Translational Bio-Imaging Center Core Facility (RRID:SCR_022428) Copy   

•   Source: SciCrunch Registry

https://wp.uthscsa.edu/mass-spec/

Mass Spectrometry for protein and small molecule analyses. Services cover full range from sample preparation through data processing and interpretation. Analyses include molecular mass determination, protein identification, protein relative quantification, localization of covalent protein modification and targeted quantitative metabolomics.Uses iLab.

Proper citation: University of Texas Health Science Center at San Antonio Mass Spectrometry Core Facility (RRID:SCR_022669) Copy   

•   Source: SciCrunch Registry

https://vrc.med.upenn.edu/vrc-facilities/machine-shop/

Designes and buildes novel instruments and apparatus for research to user specifications. Works with users to develop initial project drawing, and will explore alternate designs to insure desired functionality. Fabricates user devices to high tolerance, using machine tools and materials, and can repair laboratory devices even if devices were constructed elsewhere.

Proper citation: University of Pennsylvania Perelman School of Medicine MINS Machine Shop Core Facility (RRID:SCR_022425) Copy   

•   Source: SciCrunch Registry

https://www.pennmedicine.org/departments-and-centers/department-of-radiology/radiology-research/labs-and-centers/quantitative/physics-and-instrumentation-group

Core focuses on imaging in nuclear medicine, and engages in collaboration with clinicians and research investigators to optimize new instruments for applications in both clinical and pre clinical (animal) imaging scenarios. Offers equipment to build, test and characterize detectors for PET imaging, operates cluster of high powered Linux computers, which reconstruct, process, and analyze imaging data. Focuses on technology, which increases signal to noise of reconstructed images for whole body studies. Conducts research on SPECT imaging with emphasis on applications to small animal and brain imaging, oversees operation of cyclotron and imaging probe synthesis facilities.

Proper citation: University of Pennsylvania Perelman School of Medicine Nuclear Medicine Physics and Instrumentation Group Core Facility (RRID:SCR_022423) Copy   

•   Source: SciCrunch Registry

https://www.med.upenn.edu/pmi/facilities/muscle-physiology-assessment-core

Core provides investigators with customizable tools and methodolgies to assess in vivo exercise performance, metabolism and respiratory function, as well as in vivo and ex vivo muscle contractility. Provides guidance and training to investigators who want to learn how to collect and process muscle samples for specific uses.

Proper citation: University of Pennsylvania Perelman School of Medicine Muscle Physiology Assessment Core Facility (RRID:SCR_022422) Copy   

•   Source: SciCrunch Registry

https://www.dental.upenn.edu/research/core-facilities/live-cell-imaging-core/

Offers wide array of live cell imaging applications.Provides Nikon A1R Laser Scanning Confocal Microscopy system equipped with 4 laser lines to provide 6 different excitation/emission configurations; multiple photomultiplier tubes (PMTs), 32-channel spectral detector, full complement of microscope objectives, high speed image scanner, fully motorized stage and completely controllable environmental chamber. Users have access to NIS Elements AR software and 2D/3D deconvolution module offering sophisticated image analysis and processing features.

Proper citation: University of Pennsylvania Penn Dental Medicine Live Cell Imaging Core Facility (RRID:SCR_022442) Copy   

•   Source: SciCrunch Registry

https://www.vet.upenn.edu/research/core-resources-facilities/transgenic-mouse-core

Offers embryological manipulation services, focused on, but not limited to, murine model systems. These services primarily enable generation of genetically modified murine models, as well as experimental research in germ cell function and early embryonic development.

Proper citation: University of Pennsylvania Penn Vet Transgenic Mouse Core Facility (RRID:SCR_022441) Copy   

•   Source: SciCrunch Registry

https://lipidomics.wayne.edu

Conducts comprehensive analysis of cellular lipids that encompass fatty acyls, glycerolipids, glycerophospholipids, sphingolipids, sterol lipids, and prenol lipids.

Proper citation: Wayne State University School of Medicine Lipidomics Core Facility (RRID:SCR_022682) Copy   

•   Source: SciCrunch Registry

http://cils.northeastern.edu/facilities

Located in ISEC research center and includes advanced imaging instruments. CILS has three core facilities: Microscopy Core (confocal/multi-photon/lightsheet microscopes), Flow Cytometry Core (cell analyzer/sorter) and Preclinical Imaging Core (3T small animal MRI and ultrasound).

Proper citation: Northeastern University Institute for Chemical Imaging of Living Systems Core Facility (RRID:SCR_022681) Copy   

•   Source: SciCrunch Registry

https://ldi.upenn.edu/fellows/fellows-resources/data-and-analytics-support/

Provides secure environment for investigators analyzing protected health information. �It coordinates acquisition, storage, and analysis of data from private and government sources (e.g., Medicare, Medicaid, and others) and facilitates their use by researchers who seek to answer important questions regarding health policy and health care.�

Proper citation: University of Pennsylvania Leonard Davis Institute of Health Economics Health Services Research Data Center Core Facility (RRID:SCR_022439) Copy   

•   Source: SciCrunch Registry

https://www.vet.upenn.edu/research/core-resources-facilities/comparative-pathology-core

Provides support to investigators utilizing animal models to study disease. Comparative Pathology Core, Abramson Cancer Center shared resource, provides expert pathological characterization and validation of mouse and other animal models used in biomedical research by offering expertise of board certified veterinary pathologists and access to histology, immunohistochemistry, and digital pathology services.

Proper citation: University of Pennsylvania Penn Vet Comparative Pathology Core Facility (RRID:SCR_022438) Copy   

•   Source: SciCrunch Registry

https://ldi.upenn.edu/fellows/fellows-resources/data-and-analytics-support/

Provides LDI affiliated investigators access to high quality, skilled data analysts. HEDAP recruits, trains, and manages group of masters level and PhD level statistical analysts. These analysts work with multi disciplinary investigators across funded projects using statistical software packages such as SAS, Stata, and R to manipulate and analyze health care data under guidance of investigators and other collaborators.

Proper citation: University of Pennsylvania Leonard Davis Institute of Health Economics Data Analyst Pool Core Facility (RRID:SCR_022437) Copy   

•   Source: SciCrunch Registry

https://www.vet.upenn.edu/research/core-resources-facilities/imaging-core

Provides access to optical imaging capabilities for researchers at the University of Pennsylvania, Perelman School of Medicine, Children's Hospital of Philadelphia, and Wistar Institute. Provides instruments and expertise to perform widefield, confocal, multiphoton/intravital imaging, fluorescence lifetime imaging, high content live cell screening, long term single cell imaging, second harmonic imaging, structured illumination super resolution, and total internal reflection fluorescence microscopy, as well as software tools for image analysis. Core has adjacent (in and out) ULAR approved facility to house animals for long term live animal studies.

Proper citation: University of Pennsylvania Penn Vet Imaging Core Facility (RRID:SCR_022436) Copy   

•   Source: SciCrunch Registry

https://www.vet.upenn.edu/research/core-resources-facilities/animal-model-core-corl

Supports discovery to invention to innovation in medical translation.Provides animal model development to enhance scientific rigor during in vivo studies in experimental or naturally occurring disease models. Studies can start on small scale leading towards pivotal non-clinical IND/IDE-enabling trials in support of FDA or OUS-FDA submissions. Core hosts PIs, trainees and sponsors during clinical procedures to support and enrich their experience in cross functional team setting.

Proper citation: University of Pennsylvania Animal Model Core Facility (RRID:SCR_022435) Copy   

•   Source: SciCrunch Registry

https://med-upenn.corefacilities.org/service_center/5129/?tab=about

Offers Illumina sequencing and bioinformatic expertise to assist researchers�with gene therapy trial evaluations, viral integration profiling,�CRISPR off-target�analyses. Assists with bioinformatic analyses including RNAseq transcription profiling�and 16S taxonomic assignments.�

Proper citation: University of Pennsylvania Perelman School of Medicine Viral Molecular High Density Sequencing Core Facility (RRID:SCR_022433) Copy   

•   Source: SciCrunch Registry