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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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https://calm.mcmaster.ca/

Provides access to light microscopy, photo-patterning, and light-assisted 3D printing techniques to help researchers in science, engineering and life sciences as well as our industrial partners achieve their scientific goals.

Proper citation: McMaster University Centre for Advanced Light Microscopy Core Facility (RRID:SCR_022312) Copy   


https://www.med.upenn.edu/carc/

Core provides services to users for performing precision, image guided radiotherapy with both Photons and Protons (including FLASH proton radiotherapy) on cells, rodents and larger animals. Physicists will provide expert dosimetry and treatment planning capabilities. Instrumentation consists of two image guided SARRP 200 Small Animal Radiation Research Platforms (Xstrahl) capable of irradiating rodent tissues from 1 mm-20 mm in diameter; research proton beamline (IBA, Roberts Proton Center); one X-RAD 320ix cabinet x-ray irradiator (Precision X-Ray); and two Cs gamma-ray irradiators (Shepherd Mark I), suitable for whole body radiation of rodents.

Proper citation: University of Pennsylvania Perelman School of Medicine Cell and Animal Radiation Core Facility (RRID:SCR_022377) Copy   


https://www.jurado-lab.com/absl3

Facility offers procedural and animal housing to perform in vivo research with biosafety level 3 pathogens, such as SARS-CoV-2. Services include consultation, specialized training, and basic/advanced technical services. Provides equipment to longitudinally monitor mice over course of infection. Animal housing space includes three ABSL-3 separate housing cubicles with Allentown BCU-2 animal cages. Animals will be housed under pathogen free conditions at AAALAC accredited University Laboratory Animal Resources facilities within Vernon and Shirley Hill Pavilion using animal protocols approved by Institutional Animal Care and Use Committee.

Proper citation: University of Pennsylvania Perelman School of Medicine Animal Biosafety Level 3 Core Facility (RRID:SCR_022372) Copy   


https://www.med.upenn.edu/idom/drc/cores/ria.html

Core offers immunoassay, metabolite, and HPLC services to basic, translational, and clinical investigators performing diabetes and related metabolic disease research.RIA /Biomarkers Core is located on the 12th floor of Smilow Center for Translational Research.Approximately 100 different diabetes, obesity and metabolism-related biomarkers from multiple species including human can be assayed using radioimmunoassay (RIA), enzyme-linked immunosorbent assay (ELISA, both absorbance and fluorometric), multiplex ELISA on the Luminex platform, and enzymatic and HPLC methods for an expanding variety of diabetes and metabolism related metabolites, hormones, catecholamines and cytokines derived from blood, urine, and tissue samples.

Proper citation: University of Pennsylvania Perelman School of Medicine Radioimmunoassay and Biomarkers Core Facility (RRID:SCR_022405) Copy   


https://www.itmat.upenn.edu/bmic/

Supports next generation infrastructure for clinical data storage and management, next generation analytics, next generation infrastructure for support of clinical research including new clinical trials management system and software, next generation infrastructure for centralizing and integrating external sources of data such as genomics data. Enables future clinical and translational research through biomedical informatics education and training targeted at graduate students, postdoctoral students, residents, fellows, as well as faculty across the biomedical research spectrum.

Proper citation: University of Pennsylvania Perelman School of Medicine Center for BioMedical Informatics Core Facility (RRID:SCR_022401) Copy   


https://www.med.upenn.edu/cpob/biostatistical-consulting.html

Service supports consultation and collaboration in areas of biostatistics and epidemiology to Penn vision scientists. Biostatisticians and data management experts provide advice on study design, and offer services in sample size determinations, data management, data analysis, data interpretation, and data presentation. They are active participants in the development and writing of grant applications and manuscripts.Consulting personnel are CPOB members. In addition to their methodological and technical expertise, consultants are knowledgeable about ocular conditions under study in Penn vision community, about commonly used measures that are unique to vision research (visual acuity, refractive error, visual field indices, etc) and specialized statistical analysis techniques required for many experimental designs used in vision research (correlated data techniques to handle appropriately data from two eyes of same subject). Majority of projects are patient oriented researchers,however, CPOB Consulting Service also works on data analysis with bench laboratory scientists.

Proper citation: University of Pennsylvania Perelman School of Medicine Center for Preventive Ophthalmology and Biostatistics Biostatistical Consulting Core Facility (RRID:SCR_022400) Copy   


https://pathbio.med.upenn.edu/hic/site/

Core provides wet bench expertise and infrastructure support for early phase�clinical trials and other investigations. Offers purified cell subsets from healthy human apheresis donors. �HIC staff are qualified to�perform blood (PBMC)�and tissue processing for viable cryopreservation following validated�standard operating procedures. Offers�range of immunological assays including digital ELISA, ELISA, ELISPOT, Luminex, flow cytometry and immune repertoire profiling (NGS of BCR and TCR rearrangements in bulk and single cell formats).Offers investigators expertise and guidance in clinical trial sample processing, regulatory compliance, immunology assay design and validation, data analysis and grant writing support.

Proper citation: University of Pennsylvania Perelman School of Medicine Human Immunology Core Facility (RRID:SCR_022380) Copy   


https://www.chla.org/research/extracellular-vesicle-core

Core provides isolation, characterization, and analysis of extracellular vesicles and other nano sized particles.

Proper citation: University of Southern California CHLA Extracellular Vesicle Core Facility (RRID:SCR_022143) Copy   


https://med-upenn.corefacilities.org/service_center/4311/?tab=requests

Our core, which is part of the PennCHOP Microbiome Program, provides access for researchers to small experimental isolators for variety of in vivo studies using germ free mice. Core personnel provide technical support for germ-free experiments. New addition to core is state-of-the-art Isocage system.

Proper citation: University of Pennsylvania Perelman School of Medicine Penn Gnotobiotic Mouse Core Facility (RRID:SCR_022384) Copy   


https://ngsc.med.upenn.edu/#/

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on December 10,2025. Core provides services related to single cell and bulk whole genome, RNA-Seq, ATAC-Seq, BIS-Seq, Exome-Seq, ChIP-Seq, CLIP-Seq, etc.Provides Illumina NovaSeq 6000 in addition to NextSeq and MiSeq sequencers - which all feature self-service as well as full-service operation. Offers experience with difficult, low input samples as well as sequencing and analyzing novel library types. Small Oxford Nanopore sequencer allows for full-length RNA or cDNA sequencing as well as very long read (100KB) sequencing from genomes. Offers experimental design services prior to starting your experiment.

Proper citation: University of Pennsylvania Perelman School of Medicine Next Generation Sequencing Core Facility (RRID:SCR_022382) Copy   


https://www.med.upenn.edu/cvi/metabolomics-core.html

Core is overseen by Cardiovascular Institute and is partnership with the Abramson Cancer Center and the Institute for Diabetes, Obesity and Metabolism at Penn. Provides expertise in targeted and untargeted metabolomics of biological samples using liquid chromatography/mass spectrometry. Performs assays and assists in interpretation of results.

Proper citation: University of Pennsylvania Perelman School of Medicine Metabolomics Core Facility (RRID:SCR_022381) Copy   


https://www.med.upenn.edu/cores/assets/user-content/documents/HTSC_overview_27May2015.pdf

Core provides distribution of lentivirus based shRNA and cDNA plasmid DNA clones; technical expertise in developing biological assays (i.e. biochemical-, cell-, and high-content) in miniaturized, multiwell microtiter plates that are laboratory automation compatible; high-throughput chemical and functional genomic screening, including data analysis and interpretation. Our goal is to use cutting biological models to discover genes and small molecules that enable scientists to further study functions of poorly understood proteins, signaling pathways, and cells in complex biological process relevant to human physiology and disease.

Proper citation: University of Pennsylvania Perelman School of Medicine High Throughput Screening Core Facility (RRID:SCR_022379) Copy   


https://www.janelia.org/support-team/light-microscopy

Facility is open to Janelia scientists. Houses microscopes and multiple workstations dedicated to image processing.

Proper citation: Howard Hughes Medical Institute at Janelia Research Campus Light Microscopy Core Facility (RRID:SCR_022103) Copy   


https://cds.vanderbilt.edu

Shared Resource that offers bioinformatics and informatics services for basic research and clinical projects.

Proper citation: Vanderbilt University Creative Data Solutions Core Facility (RRID:SCR_022366) Copy   


http://researchservices.pitt.edu/facilities/microscopy-and-imaging-suite

Facility equipped with instruments for optical and electron microscopy, and Flow Cytometry.Offers experimental design, equipment training, staff operated image acquisition, and image analysis. All users must be trained by Facility staff to access the equipment.

Proper citation: University of Pittsburgh Microscopy and Imaging Suite Core Facility (RRID:SCR_022084) Copy   


https://www.umass.edu/ials/biophysical-characterization

Provides expertise and access to instruments for study of structures and interactions of biological macromolecules such as proteins, nucleic acids, lipids, and complexes. Facility supports both discovery based research and assay development for translational applications. Offers to use equipment independently or with the help of faculty who have expertise in each method.

Proper citation: University of Massachusetts Amherst Biophysical Characterization Core Facility (RRID:SCR_022357) Copy   


https://www.mines.edu/shared-facilities/cores/#XPS

Core to measure material surface compositions by measuring intensity of photoelectrons emitted as function of incident X-ray energy. Spectra features are used to identify surface species present and calculate fraction of surface occupied by each.Rocky Mountain E-XPS extends these traditional capabilities by enabling measurements in range of environmental conditions.

Proper citation: Colorado School of Mines Shared Instrumentation Facility Rocky Mountain Environmental X-Ray Photoelectron Spectroscopy Core Facility (RRID:SCR_022050) Copy   


https://qb3.berkeley.edu/facility/genomics/

Partnership between Vincent J. Coates Genomics Sequencing Laboratory,Functional Genomics Laboratory, and Computational Genomics Resource Laboratory. Offers consultation on experimental design and data analysis, full suite of technical services related to high throughput sequencing and genomics experiments, and access to high performance computational infrastructure.

Proper citation: University of California at Berkeley QB3 Genomics Core Facility (RRID:SCR_022170) Copy   


http://www.mri.cnrs.fr

Cell imaging facility of Montpellier area, France.Offers access to cutting edge instruments for optical and electron microscopy, flow cytometry, and X-ray micro tomography. Instruments are housed in seven sites that mirror distribution of Life Science research campuses of the region. Mission is to support research by offering imaging instruments and image analysis solutions.

Proper citation: Montpellier Imagining Resources MRI Core Facility (RRID:SCR_022290) Copy   


https://www.mines.edu/shared-facilities/cores/#MS

Liquid Chromatography Mass Spectrometry is analytical technique for determining ion mass-to-charge ratio by partitioning particles within liquid and measuring time it takes for each particle to travel through selected mobile phase. Ultimately this helps in determining contents of liquid sample and can be used to analyze biochemical, organic and inorganic compounds.

Proper citation: Colorado School of Mines Shared Instrumentation Facility Liquid Chromotography Mass Spectrometry Core Facility (RRID:SCR_022052) Copy   



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