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https://www.cancer.columbia.edu/research/shared-resources/confocal-and-specialized-microscopy

Advanced microscope systems for multidimensional optical imaging of living and fixed cells and tissues. Microscopy technologies include confocal, super-resolution (Airyscan and SMLM), TIRF, and wide-field microscopy as well as plate reading and laser capture microdissection. Analysis workstation and software are available, with custom pipeline development for processing, analysis, and visualization.

Proper citation: Columbia University Confocal and Specialized Microscopy Shared Resource Core Facility (RRID:SCR_026353) Copy   

•   Source: SciCrunch Registry

https://www.augusta.edu/research/core/therapeutics-core.php

Core offers services including assay development, FDA-drug library screening, unbiased compound screening, high-content imaging and screening. Facility can empower researchers to repurpose existing FDA-approved drugs and discover new compounds for drug development. Provides affordable platform for discovering therapeutic targets and interventions, supporting drug development from target identification to screening and validation. Features HTS facilities, including Biomek i7 Liquid Handling system, Pherastar FSX plate reader, ImageXpress Micro Confocal, and Pala cell sorter.

Proper citation: Augusta University Therapeutics Core Facility (RRID:SCR_026475) Copy   

•   Source: SciCrunch Registry

https://www.research.uky.edu/mass-spectrometry-and-proteomics-core

Mass spectrometry core lab performing proteomics, small molecule, and lipidomic analyses. Provides access to advanced analytical equipment for quantitation and structural analysis. Offers assistance in sample preparation, method development, acquisition, and data analysis.

Proper citation: University of Kentucky Research Mass Spectrometry and Proteomics Core Facility (RRID:SCR_026359) Copy   

•   Source: SciCrunch Registry

https://sites.google.com/fieldmuseum.org/research/laboratories/core-laboratories/dna-clean?authuser=0

Facility dedicated to study of degraded and low DNA yield samples, such as environmental DNA, historical DNA, or ancient DNA. Offers positive pressure lab spaces that follow strict decontamination procedures to prevent human, bacterial, and fungal contamination. It is physically isolated from tissue samples or polymerase chain reaction (PCR) products to avoid contamination from samples with higher DNA concentration and quality. The space has dedicated equipment necessary for DNA extraction and PCR-free sample preparation.

Proper citation: Field Museum of Natural History Biomolecular Clean Laboratory Core Facility (RRID:SCR_026364) Copy   

•   Source: SciCrunch Registry

https://www.nuance.northwestern.edu/facilities/keck-ii/index.html

Core facilitates research, collaboration, education and outreach in all science from soft biological matter to hard physical matter, specializing in surface analysis and nano-scale characterization. Instruments include Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS), X-ray Photoelectron Spectroscopy (XPS), Fourier Transform Infrared Spectroscopy (FT-IR), Confocal Raman System, High Resolution Stylus Profilometer, 3D Optical Microscope, Spectroscopic Ellipsometer, and Zetasizer.Staff provides hand-on training, collaboration and assistance.

Proper citation: Northwestern University Keck Interdisciplinary Surface Science Core Facility (RRID:SCR_026360) Copy   

•   Source: SciCrunch Registry

https://nextgen.mgh.harvard.edu/Pricing.html

Core offers sequencing, upstream library construction (bulk RNA/DNA, single-cell), and post-sequencing analysis. Core uses Illumina NextSeq 2000 sequencers (and a MiSeq). Single-cell (fresh, frozen, FFPE) libraries (3' & 5' RNA-Seq, CITE-Seq, ATAC-Seq, Multiome, FLEX) are made with 10X Chromium X.

Proper citation: Massachusetts General Hospital NGS Core Facility (RRID:SCR_026362) Copy   

•   Source: SciCrunch Registry

https://www.ucl.ac.uk/biosciences/research/research-facilities/molecular-biology/darwin-research-facility-drf

Facility provides diverse range of equipment, expertise and training in field of biochemistry, molecular, structural and cellular biology. Facility consists of several research laboratories and support areas.

Proper citation: University College London Darwin Research Core Facility (RRID:SCR_026345) Copy   

•   Source: SciCrunch Registry

https://www.mdanderson.org/research/departments-labs-institutes/institutes/zayed-institute-for-personalized-cancer-therapy/ipct-genomic-laboratory.html

Provides services and instrumentation including Illumina Next-Generation Sequencing, Single Cell Analysis and Spatial Transcriptomics. These techniques are developed and optimized by our lab scientists to deliver the highest-possible quality sequencing data from a wide variety of sample types such as peripheral blood, bone marrow, fresh frozen tissue and FFPE-derived tumor samples.

Proper citation: University of Texas Institute for Personalized Cancer Therapy Cancer Genomics Laboratory Core Facility (RRID:SCR_026469) Copy   

•   Source: SciCrunch Registry

https://centers.louisville.edu/brown-cancer-center/core-facilities/medicinal-chemistry

Core Facility provides essential medicinal and organic chemistry support for drug discovery. The core specializes in the lead optimization of an initial lead compound to improve biological activity and drug-like properties, and to elucidate structure activity relationships. Other services include the design and synthesis of fluorescent and isotopic probes, compound scale up (1 – 5 grams), and custom synthesis.

Proper citation: University of Louisville Medicinal Chemistry Core Facility (RRID:SCR_026397) Copy   

•   Source: SciCrunch Registry

https://prisme.institutducerveau.org/

Core facility dedicated to the study of human cognition and normal and pathological human behavior either via computer tests or in simulations, including using virtual reality.

Proper citation: Paris Brain Institute PRISME Core Facility (RRID:SCR_026394) Copy   

•   Source: SciCrunch Registry

https://ephys.institutducerveau.org/

Core develops solutions to meet your needs in electrophysiology data. Provides electrophysiology services to the neuroscience scientific community. Core has standard recording equipment such as patch clamp techniques or electroencephalographic (EEG) recordings.

Proper citation: Paris Brain Institute Electrophysiology Core Facility (RRID:SCR_026412) Copy   

•   Source: SciCrunch Registry

https://www.seattlechildrens.org/research/resources/behavioral-phenotyping-core/

Core dedicated to the protocol driven collection, analysis, and reporting of behavioral data using a blend of classic and innovative assays. Supports neuroscience, psychology, pharmacology, genetics, cancer, and development by providing advanced tools and expertise for the precise measurement and interpretation of behavior.

Proper citation: Seattle Childrens Research Institute Behavioral Phenotyping Core Facility (RRID:SCR_026371) Copy   

•   Source: SciCrunch Registry

https://touchstonelabs.org/metabolic-phenotyping-core

Academic core facility provides analytical and phenotypical measures to the scientific community. Provides services related to metabolic disorders (diabetes and obesity), cancer, aging neurological disorders, etc. Provides letters of support for grant proposals and research applications.

Proper citation: University of Texas Southwestern Medical Center Dallas Metabolic Phenotyping Core Facility (RRID:SCR_026404) Copy   

•   Source: SciCrunch Registry

https://okinbre.ouhsc.edu/Core-Facilities#Bioinformatics

Core provides data science analysis support, training and promotion of data science education for undergraduate and high school students in the state of Oklahoma. Services include 1) Global analysis of gene expression data using custom spotted microarrays and commercial Affymetrix and Combimatrix arrays to examine gene expression patterns in mice, adenovirus-infected cells, and a variety of bacterial systems. 2) Genome annotation and comparative genomics analysis, including studies on several bacterial and viral pathogens important for human and agricultural disease. Informatics support for genome sequencing projects, annotation support, and post-sequence studies. Bioinformatics educational include analysis of laboratory data for DNA barcoding, instructional materials for protein structure analyses and phylogenetic analyses, and microbial and viral genome sequence annotation and analysis, career counseling to undergraduate students, both individually and in large groups, supervision of undergraduate summer interns and high school interns to enhance interest in pursuing bioinformatics as a career path, providing instructional materials for high school teachers interested in incorporating bioinformatics into their lesson plans.

Proper citation: University of Oklahoma Health Sciences Center OK INBRE Data Science Core Facility (RRID:SCR_026422) Copy   

•   Source: SciCrunch Registry

https://nuance.northwestern.edu/facilities/spid/index.html

SPID provides imaging instrumentation and support facilities for atomic to molecular imaging. Supports broad range of nanoscale science and technology characterization needs at nanoscale by providing resources coupled with expert staff. Research at SPID encompasses physical and chemical sciences, engineering and life sciences, and has a strong inter-disciplinary emphasis.

Proper citation: Northwestern University NUANCE SPID Core Facility (RRID:SCR_026380) Copy   

•   Source: SciCrunch Registry

https://my.ilabsolutions.com/service_center/show_external/3232/

Core provides access to technology, experience, and expertise in molecular biology methods.Offers expertise in bioinformatics needed to acquire, analyze, and visualize data generated from high throughput technologies used in genomics research. Services include Illumina sequencing,Bioinformatics and statistical analysis,PacBio sequencing,Oxford Nanpore sequencing,High-throughput DNA and RNA library preparation,Double-barcoded amplicon sequencing. GBRC also participates in many of the bioinformatic analyses from the projects including De novo genome and transcriptome assembly, RNAseq differential expression analysis, SNP calling, RAD sequence analysis, Dual-barcoded amplicon community analysis, Phylogenetic analysis, CRISPR transformant profiling,Speed congenics, Novel agriculture virus detection and assembly.

Proper citation: University of Idaho IIDS Genomics and Bioinformatics Resource Core Facility (RRID:SCR_026416) Copy   

•   Source: SciCrunch Registry

https://www.augusta.edu/cancer/research/shared-resources/immune-monitoring/

Core provides services in Assay Development, Assays Experimental Design, Immune Monitoring, Cytokine Assays, ELISA, multiplex Flow based and Luminex based Bead Arrays, Project Based Flow Cytometry and Data Analysis.

Proper citation: Augusta University Georgia Cancer Center Immune Monitoring Shared Resource Core Facility (RRID:SCR_026590) Copy   

•   Source: SciCrunch Registry

https://cvvr.hms.harvard.edu/cvvr-research-program/#hiv-1-neutralizing-antibody-core

Core provides in vitro HIV-1 neutralizing antibody assay services. Serves as resource for assessing breadth and potency of HIV-1 neutralizing antibodies, and for characterizing neutralization phenotype of HIV-1 isolates. Investigators send monoclonal antibodies or serum samples from vaccinated or HIV-1-infected individuals to the core for in vitro testing using the validated TZM.bl neutralizing antibody assay. The core also has the capability to phenotype primary HIV-1 isolates for sensitivity to broadly neutralizing antibodies. GCLP-compliant, In vitro testing of monoclonal antibodies or seurm samples, Validated TZM.bl neutralizing antibody assay, Phenotoyping of primary HIV-1 isolates.

Proper citation: Harvard University School of Medicine BIDMC HIV-1 Neutralizing Antibody Core Facility (RRID:SCR_026484) Copy   

•   Source: SciCrunch Registry

https://centers.louisville.edu/brown-cancer-center/core-facilities/nmr

Core Facility houses 600 MHz Bruker Avance Neo NMR spectrometer available for both collaborative and fee-for-service use. The facility is equipped with a 14.1 T Bruker system and a nitrogen-cooled Prodigy probe, enabling a range of 3D experiments on isotopically labeled biomolecules with enhanced sensitivity for challenging samples. Services include biomolecular structure determination, characterization of biomolecular motions, and stable isotope-resolved metabolomics for studying metabolic pathways.

Proper citation: University of Louisville Nuclear Magnetic Resonance Spectroscopy Core Facility (RRID:SCR_026517) Copy   

•   Source: SciCrunch Registry

https://www.bcchr.ca/imagingcore

Core is multi-user facility located on the 4th floor in the Translational Research Building (TRB) at A4-110. It houses microscopes and image data analysis computers to provide imaging for wide range of samples, including cell structures in tissue sections, and subcellular structures and 3D morphologies of single cells. A full-time technician provides training, consultation, and guidance to researchers, from sample preparation to data analysis.

Proper citation: University of British Columbia BCCHR Imaging Core Facility (RRID:SCR_026573) Copy   

•   Source: SciCrunch Registry