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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://www.iowadonornetwork.org/
A nonprofit organ procurement agency based in Iowa. The organization facilitates both organ and tissue recovery in cooperation with local hospitals. The network also works to support public education, hospital development and family support services.
Proper citation: Iowa Donor Network (RRID:SCR_000548) Copy
http://www.dian-info.org/default.htm
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 23,2022. An international research partnership of leading scientists determined to understand a rare form of Alzheimers disease that is caused by a gene mutation and to establish a research database and tissue repository to support research on Alzheimers disease by other investigators around the world. One goal of DIAN is to study possible brain changes that occur before Alzheimers disease is expressed in people who carry an Alzheimers disease mutation. Other family members without a mutation will serve as a comparison group. People in families in which a mutation has been identified will be tracked in order to detect physical or mental changes that might distinguish people who inherited the mutation from those who did not. DIAN currently involves eleven outstanding research institutions in the United States, United Kingdom, and Australia. John C. Morris, M.D., Friedman Distinguished Professor of Neurology at Washington University School of Medicine in St. Louis, is the principal investigator of the project., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: DIAN - Dominantly Inherited Alzheimer Network (RRID:SCR_000812) Copy
A not for profit organization to accelerate research into aging by sharing resources: providing access to cost and time effective, aged murine tissue through a biorepository and database of live ageing colonies, as well as promoting the networking of researchers and dissemination of knowledge through its online collaborative environment; MiCEPACE. ShARM will provide valuable resources for the scientific community while helping to reduce the number of animals used in vital research into aging. The biobank of tissue and networking facility will enable scientists to access shared research material and data. By making use of collective resources, the number of individual animals required in research experiments can be minimized. The project also has the added value of helping to reduce the costs of research by connecting scientists, pooling resource and combining knowledge. ShARM works in partnership with MRC Harwell and the Centre for Intergrated Research into Musculoskeletal Ageing (CIMA).
Proper citation: ShARM (RRID:SCR_003120) Copy
https://ndriresource.org/for-researchers/services-capabilities-sample/htorr
NDRI’s Human Tissue and Organs for Research Resource (HTORR) Program has been funded by the National Institutes of Health (NIH) for over 30 consecutive years to support research programs across multiple disciplines. It is through the HTORR program that NDRI provides academic biomedical investigators with donated normal and diseased human tissues and organs recovered from a diverse donor pool using customized procurement, processing, and preservation and distribution protocols. Our HTORR Program supports academic biomedical research investigators needs by providing: Access to a wide array of human biospecimens from any body system * Customized procurement in a variety of preservation formats including fresh, frozen, and fixed suitable for various analytical techniques * Reduced costs for tissue procurement * Technical support to design your studies utilizing human biospecimens * Letters of support and budgetary information for grant applications
Proper citation: Human Tissue and Organ for Research Resource (HTORR) (RRID:SCR_002859) Copy
Consortium serving the diabetic complications community that sponsors annual meetings in complications-relevant scientific areas, solicits and funds pilot projects in high impact areas of complications research, and provides resources and data including animal models, protocols and methods, validation criteria, reagents and resources, histology, publications and bioinformatics for researchers conducting diabetic complications research.
Proper citation: Diabetic Complications Consortium (RRID:SCR_001415) Copy
http://bioinformatics.istge.it/cldb/indexes.html
Hypertext on cell culture availability extracted from the Cell Line Data Base of the Interlab Project. HyperCLDB includes links to records of OMIM, the Online Mendelian Inheritance in Man Catalogue, and now also links to the PubMed, database of bibliographic biomedical references, which are drawn primarily from MEDLINE and PREMEDLINE.
Proper citation: Hyper Cell Line Database (RRID:SCR_007730) Copy
http://www.nia.nih.gov/research/nonhuman-primate-tissue-bank-handbook
A repository of tissue collected from nonhuman primate (NHP) species under contractual arrangement with Wisconsin National Primate Research Center (WI NPRC). NIA''''s Nonhuman Primate Tissue Bank collects and archives tissue from necropsies performed at primate centers nationwide. The goal is to collect various tissues from aged monkeys with smaller amounts of the same tissues from young and middle-aged monkeys. Tissue will be provided as: (1) fresh frozen, stored at ����?��������??80 degrees Celsius; (2) formalin fixed; or (3) fresh frozen tissue in OCT medium.Most frozen tissues are provided in approximately 1 gram of tissue per vial. Fixed tissue is available as slides (sections) from paraffin-embedded blocks. Slides can be stained if requested. Tissue from NIA''''s Nonhuman Primate Tissue Bank is available to investigators at academic and nonprofit research institutions who are engaged in funded research on aging. The project name and funding source must accompany all orders. The NIA will not be able to ship non-human primate tissue outside of the United States or US territories. Investigators at for-profit entities are not eligible to purchase tissue from NIA''''s Nonhuman Primate Tissue Bank unless it is for a Small Business Innovation Research grant from NIA. NIA provides the health information as given by the donor site and cannot guarantee other aspects of the health status not explicitly stated in the Vital Statistics Information Sheet. Concerns about the specific health status of donor animals should be indicated on the order form.
Proper citation: NIA Nonhuman Primate Tissue Bank (RRID:SCR_007324) Copy
http://www.cnio.es/ES/grupos/plantillas/presentacion.asp?grupo=50004308
THIS RESOURCE IS NO LONGER IN SERVICE, documented August 29, 2016. The need to use human neoplastic tissue under ideal conditions is currently of particular importance due to the development molecular pathology techniques that allow large-scale studies of genetic expression that are also of clinical significance. The Tumour Bank Network (TBN), instigated and coordinated by the Molecular Pathology Programme (MMP) aims to respond to this need by the promoting of Tumour Banks in Spanish hospitals. This will be achieved through the application of homogeneous procedures for the collection, processing and storage of neoplastic and normal tissue samples in such a way as to make molecular studies possible, avoiding that avoid the intrinsic bias of multi-centre studies possible. These Hospital Tumour Banks are based within the Pathology Departments of the collaborating Hospitals, that are interconnected through a computer-based network. In this way, each Centre''s tissue remains in the Hospital itself, thereby playing a key role in the development of the welfare, teaching and research activities within the Hospital. At the same time, it represents a tool to encourage of multi-hospital cancer research and of cooperation between basic and clinical researchers, constituting important collaboration between biomedical disciplines. The design does not correspond to a Central Tumour Bank, but that of a cooperative and coordinated Network of Hospital Banks, based on simple, homogeneous and optimal tissue treatment protocols. This Network is promoted by the Centro Nacional de Investigaciones Oncologicas (CNIO), which thereby undertakes the work of coordinating the network, using and maintaining the database, adhering to quality control. The aim of the CNIO's TBN is to acquire neoplastic and control non-neoplastic material of all types of malignant neoplasias, in the form of tissue fixed in formalin and paraffin embedded, of samples that are unfixed or frozen according to conventional methods as set out in Annexe 1 and even, exceptionally as fresh tissue. When other types of samples are required to carry out a specific project, the central office of the TBN will draw up a protocol with the group leading the project for the collection and maintenance of the tissue and clinicopathological data required for the proposed research. These protocols will be disseminated among the Associated Hospitals in order to gather the previously agreed number cases. Basic data surrounding the processing and preservation conditions for each case will be sent to the central office of the Bank, which under no circumstances will reveal the identity of the patient. Any Spanish cancer research team will be able to request tissue from the Tissue Bank Network. Absolute priority will be afforded to projects whose principal researcher belongs to one of the Associated Centres of the TNB, to other institutions with special agreements concerning the exchange of samples, and to the CNIO's researchers.
Proper citation: Spanish National Tumour Bank Network (RRID:SCR_008707) Copy
Provides sterile biologic implants of human bone and tissues used in spine, sports medicine, orthopedic, dental and other specialty surgeries.
Proper citation: RTI Biologics (RRID:SCR_010721) Copy
Provides human tissue for drug discovery scientists. * Human Biospecimens: Frozen & Fixed Human Tissues; Human RNA/DNA; Human Primary Cells / Cell lines; Custom Procurement; Oncology tissue, biofluid and RNA sets at special prices * Human Tissue-Based Services: Gene Expression, Molecular Pathology, Biochemical Pharmacology, Metabolism and Toxicity * Predictive Human Disease Models
Proper citation: Asterand (RRID:SCR_010703) Copy
http://www.tissue-solutions.com/
Tissue Solutions offers you a single point to access the entire range of human biological materials for all your research and development needs. This includes diseased and normal tissues in fresh, frozen and FFPE formats. Using our large network of ethical sources we find the tissues you require, to your specifications and will deliver them to your door. Our goal is to provide high quality and well characterized samples to biotech companies, the pharmaceutical community and contract research organizations worldwide. We also organize customized and prospective tissue acquisition projects and give specialized advice relating to all aspects of the acquisition process, including intellectual input on project design. We appreciate that you would rather spend your time finding new biomarkers and developing, testing and validating novel drugs to cure human disease than spend your time sourcing material to help you do your work, so let our dedicated Tissue Acquisitionists lessen your workload and become a virtual part of your team.
Proper citation: Tissue Solutions (RRID:SCR_010672) Copy
http://www.scienceexchange.com/facilities/specimen-bank-bwh-harvard
Core facility that provides the following services: Open repositories service, Sample processing service, Medical/pathology informatics support service, BWH tissue repository service.
The Specimen Bank provides materials to investigators with IRB-approved protocols. Staff are available to assist with selection of samples appropriate for downstream applications, development of processing protocols or preparation of derivatives from clinical materials. IT Staff are also available to assist researchers with creation of queries for prospective sample collection or queries to select samples from specific cohorts. Their goal is to drive quality research in an efficient and cost-effective manner. Each year they provide tens of thousands of samples to area researchers. Getting started: Partners investigators and study staff may request a Crimson user account to help manage studies and collected materials.
Proper citation: BWH Specimen Bank (RRID:SCR_012316) Copy
http://mayovalidation.com/quality-biospecimens/
A core laboratory facility provides high-volume, high-quality tissue and biospecimen preparation and processing in support of Mayo research. Mayo Validation Support Services utilizes these resources to deliver extensive validation capabilities specific to individualized Sponsor requirements. Medical scientific expertise at Mayo Clinic allows for unique collaborations combining quality biospecimens linked to comprehensive clinical outcomes. Biospecimens can be accessed via archives or prospectively collected via individualized standard operating procedures. Patient information for all biospecimens is protected through oversight by an Institutional Review Board (IRB). Specimens may be collected and/or processed in a variety of customized formats for individual collaborations. Typical formats include: * Specimen Processing: Tissue RNA/DNA extraction capabilities, Paraffin and frozen sectioning, Immunostaining, Digital imaging, Laser capture microdissection, Tissue microarray construction, Preparation of protocol-collected tissue (FFPE, OCT, Snap-frozen, PBS) * Blood: Circulating tumor cells, Serum, Plasma, PBMC, Whole blood for FACS analysis, Blood smears * Other: Induced sputum, Saliva, Buccal swabs, Lip biopsies, Colonoscopy biopsies, Synovium, Stool, Urine Biospecimens located within archives are well-characterized and associated with phenotypic information. Multiple types and formats of biospecimens are available for customized validation purposes.
Proper citation: Mayo Validation Support Services Biobank (RRID:SCR_010745) Copy
Genetic Alliance Registry and BioBank is a centralized, clinical data registry and sample repository (including DNA, serum, cells and tissues) that enables translational research. It is a nonprofit organization established by seven patient advocacy organizations. These organizations share resources for their BioBanks, such as the contract to the independent lab that processes the samples, but each organization will maintain ownership, control and costs associated with their sample collection. Founded in 2003, this cooperative venture provides shared infrastructure and customized solutions for disease advocacy organizations to lead sophisticated research initiatives. Genetic Alliance Registry and BioBank is an advocacy owned repository for biological samples and clinical data. It provides: * Centralized, standardized collection and archiving * Highest biorepository and participant protection standards * Open access for all organization approved researchers * Advocacy organization control
Proper citation: Genetic Alliance Biobank (RRID:SCR_010625) Copy
Provides access to large scale cell culture at reasonable cost. The Cell Culture Center has experience with the production of over 1700 cell lines. Numerous common cell lines, such as HeLa, CHO, 293, BHK, and hybridomas are routinely produced at the Center. We will adapt your cell line or custom protocol to large scale production then deliver the cells in the quantity and frequency you need. Large Scale Production Services: Mammalian cells: Suspension culture (1 to 400 liters per day), Anchorage dependent culture (1 to 200 roller bottles per batch), Purified monoclonal antibodies (10 mg to 100 grams), Non-hybridoma cell secreted proteins, Conditioned media Secreted proteins from suspension cultures can be produced in automated hollow fiber bioreactor systems. These systems may be considered after initial static culture production yields are determined. Upon determining the quantities requested by the investigator, the appropriate automated system will be used. For more information on the automated instrumentation available for the use of secreted protein production, please refer to the Biovest International web page (www.biovest.com). Working with our experienced personnel and quality controlled, state-of-the-art facilities also permits access to large quantities of cells or protein so you aren''t limited by the cell culture capacities of your own laboratory. The Center fulfills the needs of small research laboratories as well as those of larger institutions. Customers from all sectors of the research and industrial community are welcome to inquire about our services. If you''d like to inquire about using our services, use the contact infromation below. Key words: Cell, cells, culture, monoclonal, antibodies, antibody.
Proper citation: National Cell Culture Center (RRID:SCR_013467) Copy
A non-profit tissue bank that facilitates the distribution of non-transplantable tissue to the medical and research community. It provides snap frozen low post mortem interval (PMI) tissue, normal and diseased tissue, plastinated specimens, anatomical specimens, and specialty specimens. The foundation also works to increase public awareness of research tissue donation for medical research.
Proper citation: LifeLegacy Foundation (RRID:SCR_000518) Copy
A dataset of a prospective panel study of health and aging in Mexico. The study was designed to ensure comparability with the U.S. Health and Retirement Study in many domains, and the NHANES III. The baseline survey in 2001 is nationally representative of the 13 million Mexicans born prior to 1951. The six Mexican states which are home to 40% of all migrants to the U.S. were over-sampled at a rate of 1.7:1. Spouse/partners of eligible respondents were interviewed also, even if the spouse was born after 1950. Completed interviews were obtained in 9,862 households, for a total of 15,186 individual interviews. All interviews were face-to-face, with average duration of 82 minutes. A direct interview (on the Basic questionnaire) was sought, and Proxy interviews were obtained when poor health or temporary absence precluded a direct interview. Questionnaire topics included the following: * HEALTH MEASURES: self-reports of conditions, symptoms, functional status, hygienic behaviors (e.g., smoking & drinking history), use/source/costs of health care services, depression, pain, reading and cognitive performance; * BACKGROUND: Childhood health and living conditions, education, ability to read/write and count, migration history, marital history; * FAMILY: rosters of all children (including deceased children); for each, demographic attributes, summary indicators of childhood and current health, education, current work status, migration. Parent and sibling migration experiences; * TRANSFERS: financial and time help given to and received by respondent from children, indexed to specific child; time and financial help to parent; * ECONOMIC: sources and amounts of income, including wages, pensions, and government subsidies; type and value of assets. All amount variables are bracketed in case of non-response. * HOUSING ENVIRONMENT: type, location, building materials, other indicators of quality, and ownership of consumer durables; * ANTHROPOMETRIC: for a 20% sub-sample, measured weight, height; waist, hip, and calf circumference; knee height, and timed one-leg stands. Current plans are to conduct another two follow-up surveys in 2012 and 2014 and will field the 3rd and 4th waves of survey data collection in Mexico. For the 2012 wave, interviews will be sought for: every person who was part of the panel in 2003 and their new spouse / partner, if applicable, and a new sample of persons born between 1952 and 1962. For the 2014 wave, we will follow-up the whole sample from 2012. Interviews will be conducted person-to-person. Direct interviews will be sought with all informants, but proxy interviews are allowed for those unable to complete their own interview for health or cognitive reasons. A next-of-kin interview will be completed with a knowledgeable respondent for those who were part of the panel but have died since the last interview. A sub-sample will be selected to obtain objective markers such as blood sample and anthropometric measures. Data Availability: The 2001 baseline data, 2003 follow-up data, and documentation can be downloaded. * Dates of Study: 2001-2003 * Study Features: Longitudinal, International, Anthropometric Measures * Sample Size: 2001: 15,186 (Baseline) Link: * ICPSR: http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/00142
Proper citation: Mexican Health and Aging Study (RRID:SCR_000818) Copy
http://www2.bsc.gwu.edu/bsc/oneproj.php?pkey=28
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 31,2025. Collect, store, and distribute genetic samples from cases and controls of type 1 diabetes and diabetic nephropathy for investigator-driven research into the genetic basis of diabetic nephropathy. As the risk of kidney complications in type 1 diabetes appears to have a considerable genetic component, this study assembled a large data resource for researchers attempting to identify causative genetic variants. The types of data collected allowed traditional case-control testing, a rapid and often powerful approach, and family-based analysis, a robust approach that is not influenced by population substructure.
Proper citation: Genetics of Kidneys in Diabetes (RRID:SCR_000133) Copy
http://ki.se/ki/jsp/polopoly.jsp?d=29346&a=31576&l=en
THIS RESOURCE IS NO LONGER IN SERVICE, documented August 23, 2016. PRACSIS (Prognosis and Risk in Acute Coronary Syndromes In Sweden) aims to study prognosis and its predictors in a consecutive series of patients with acute coronary syndrome (ACS). The study is comprised of patients between 18 and 80 years diagnosed at the coronary care unit at the Sahlgrenska University Hospital with unstable angina, non-ST-elevation MI or ST-elevation MI. Extensive information on medical history and blood samples for analyses of biochemical markers and genetic factors have been collected.
Proper citation: PRACSIS - Prognosis and Risk in Acute Coronary Syndromes In Sweden (RRID:SCR_000615) Copy
http://lgsun.grc.nia.nih.gov/cDNA/cDNA.html
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 23,2022. Project portal housing NIA Mouse EST Project, NIA Mouse cDNA Clone Sets, a NIA Mouse Gene Index, NIA Mouse cDNA Database, and NIA Mouse Microarrays. Characteristics of NIA 15K Mouse cDNA Clone Set * ~15,000 unique cDNA clones were rearrayed among 52,374 ESTs from pre- and periimplantation embryos, E12.5 female gonad/mesonephros, and newborn ovary. * Up to 50% are derived from novel genes. * ~1.5 kb average insert size. * Clones were sequenced from 5' and 3' termini to obtain longer reads and verify sequence. Sequence information is available at this Web Site. Clone names are from H3001A01 to H3159G07. * Handling of NIA 15k cDNA Clone Set(June3, 2000) Characteristics of NIA mouse 7.4K cDNA Clone Set * ~7407 cDNA clones with no redundancy within the set or with NIA Mouse 15K. * ~1.5 kb average insert size for short insert clones and ~2.5-3.0 kb average insert size for long-insert enriched clones.. * Clones were sequenced from 5' and 3' termini to obtain longer reads and verify sequence. Sequence information is available at this Web Site. Clone names are from H4001A01 to H4079G07. * Handling of NIA mouse 7.4k cDNA Clone Set (similar to handling of NIA mouse 15K, to be updated) Individual Clones are available from ATCC and MRC geneservice, UK. To obtain Clone, search the database using either the rearrayed clone name or GenBank accession number at the Key Word Search page. Follow the link to the sequence information page for the rearrayed clone to obtain source clone ATCC number. Clicking the ATCC number will bring up the ATCC ordering page for the source clone. There is essentially no overlap between the two clone sets (7.4K and 15K) said Minoru S.H. Ko, M.D., Ph.D., head of the Developmental Genomics and Aging Section in the NIA's Laboratory of Genetics. In addition, all cDNA clones in the NIA 7.4K set were purified by single colony isolation and sequence-verified, and more than half were prepared by a new procedure that yields long full-length cDNAs (average size 3-4 kb). The NIA Mouse 15k and 7.4k Clone Set Data and Published Microarray Data are available for download. NIA Mouse Microarrays *Microarray Data Download * 60-mer Oligo Array Platform ** (A) NIA 22k Oligo Microarray Gene List (21939 gene features) ( Carter et al 2003 ) ** (B) Agilent Mouse Development Oligo Microarray Gene List ** ( Subset of Microarray (A): 20,280 gene features ) * Data Analysis Tools
Proper citation: NIA Mouse cDNA Project Home Page (RRID:SCR_001472) Copy
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