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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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https://einsteinmed.edu/centers/diabetes-research/research-areas/biomedical-cores/translational-research-core/index.html

Core services include consultation, technical support and training and mentoring in clinical and translational research methods that are specifically applicable to diabetes, its complications and related metabolic disorders. Personel provides expertise in first-in-human and mechanistic studies in integrative physiology, in clinical trials of diabetes and obesity, and in application of new technologies.

Proper citation: Einstein-Mount Sinai Diabetes Research Center Translational Research Core Facility (RRID:SCR_015068) Copy   


http://drc.ucsf.edu/mouse-metabolism-core

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 10,2024. Core which provides technical support for UCSF investigators to conduct metabolic studies using a 12-chambered Comprehensive Lab Animal Monitoring System (CLAMS), an EchoMRI, and Dual energy X-ray absorptiometry, which together allow measurement of food intake, water intake, motor activities, core temperature, and body composition in live mice. It also helps to identify emerging technologies that will enhance multiple research programs and coordinates the acquisition and maintenance of those facilities.

Proper citation: University of California San Francisco Diabetes Research Center Mouse Metabolism Core (RRID:SCR_015101) Copy   


https://www.baderc.org/cores/cbmcore/

Services provided include tissue preparation, embedding and sectioning for electron microscopy, use of electron microscope and photography of thin sections, immunogold staining for electron microscopy, preparation and incubation of samples (cells and tissues) for immunofluorescence microscopy, confocal microscopy and digital imaging.

Proper citation: Boston Area Diabetes Endocrinology Research Center Cell Biology and Morphology Core Facility (RRID:SCR_015069) Copy   


https://diabetes.ucsf.edu/drc-microscopy

Core that consolidates, enhances and disseminates Diabetes Center resources and expertise in tissue and cell imaging technologies. Confocal fluorescence, widefield fluorescence, high throughput fluorescence and brightfield microscopes are available directly within the DRC Microscopy Core. Image quantification and analysis is performed at dedicated workstations.

Proper citation: University of California San Francisco Diabetes Research Center Microscopy Core Facility (RRID:SCR_015103) Copy   


http://drc.ucsf.edu/lentiviral-rnai-core

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on November 5,2024. Core that provides reagents, equipment, training, supervision, and monitoring of investigators wishing to ensure the proper compliance with biosafety containment required for lentiviral-based research, lentiviral preparation services for investigators, and education on RNAi experimentation, through the lentiviral core website, and through protocols available at the facility.

Proper citation: University of California San Francisco Diabetes Research Center Lentiviral RNAi Core Facility (RRID:SCR_015104) Copy   


http://www.baderc.org/cores/molbioCore.html

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 24,2024. Core that provides services for DNA sequencing and oligonucleotide synthesis, as well as support for projects that require research laboratory automation, such as siRNA screens and transcript abundance profiling. It also offers experimental design and advice for automation and high throughput screening of siRNA collections based on the Ambion siRNA collection.

Proper citation: Boston Area Diabetes Endocrinology Research Center Molecular Biology (RRID:SCR_015079) Copy   


https://www.derc.cuimc.columbia.edu/services/flow-cytometry-and-cell-sorting-core

Core which assists investigators to quantify and phenotypically characterize cell populations that contribute to the metabolic, immunologic and developmental programs of diabetes and its complications; and to purify populations of cells of relevance to diabetes and its complications.

Proper citation: Columbia Diabetes Research Center Flow Cytometry and Cell Sorting Core Facility (RRID:SCR_015078) Copy   


http://www.baderc.org/cores/IsletCore.html

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 23,2024.Core which provides islets to the local diabetes research community in the Boston area. They collaborate with researchers nationally to provide nonhuman primate (NHP) islets for research.

Proper citation: Boston Area Diabetes Endocrinology Research Center Pancreatic Islet (RRID:SCR_015073) Copy   


http://cdmd.indiana.edu/research-core/the-swine-core/

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 14,2024. Core which utilizes a breeding colony of Ossabaw swine with metabolic syndrome and long-term complications, most notably cardiovascular disease. It provides swine maintenance (glucose tolerance tests, body composition, glucose clamp studies, and imaging studies), characterization of cardiovascular disease (intravascular ultrasound, blood flow velocity, microvascular studies), and tissues (both banked and fresh) for analysis ex vivo.

Proper citation: Indiana Diabetes Research Center Swine Core (RRID:SCR_015089) Copy   


https://www.derc.cuimc.columbia.edu/services/mouse-metabolic-function-and-phenotyping-core

Core that provides services that facilitate the efficient characterization of mouse models of diabetes and its complications: NMR Body Composition Analysis, Whole Body Metabolic Assessment (chamber calorimetry with motion detection), Metabolic Clamps, Gastric Infusion/Feeding and Thermogenic Phenotyping.

Proper citation: Columbia Diabetes Research Center Mouse Metabolic Function and Phenotyping Core Facility (RRID:SCR_015082) Copy   


https://diabetescenters.org/cores/indiana-microscopy-core

Core that provides consultation and specialized services for intravital microscopy of pancreas and transplanted islets, FRET assays, and fluorescent biosensors for analysis of intracellular signaling cascades to serve the area diabetes investigators.

Proper citation: Indiana Diabetes Research Center Microscopy Core Facility (RRID:SCR_015083) Copy   


https://medicine.iu.edu/research-centers/diabetes/cores/islet-physiology

Services include islet isolation services from mice and rats and access to porcine and human islets. The core is equipped with BioRep Perifusion Apparatus for measurement of insulin secretion and offers services for islet and beta cell calcium imaging. Provides services for islet transplantation and assists investigators who wish to perform immunohistochemistry, immunofluorescence and/or analysis of endocrine or beta cell mass on whole pancreata from mouse and rat models.Offers services for rodent metabolic characterization, including performance of insulin and glucose tolerance testing, analysis of body composition, and metabolic cage analysis using the TSE System cages. Recently added services include zebrafish characterization to screen genes and small molecules for their effects on islet development and function.

Proper citation: Indiana University School of Medicine Center for Diabetes and Metabolic Diseases Islet and Physiology Core Facility (RRID:SCR_015081) Copy   


https://diabetescenters.org/cores/indiana-translation-core

Core within Indiana Center for Diabetes and Metabolic Diseases that offers services that facilitate conduct of research involving human subjects, including providing low-cost, high quality analyte measurements for variety of hormones, cytokines, lipids and other analytes. Its human studies services include metabolic phenotyping (e.g. GTT, clamp studies, tracer studies), and access to a biobank of human tissues and serum.

Proper citation: Indiana Diabetes Research Center Translation Core Facility (RRID:SCR_015084) Copy   


https://www.derc.cuimc.columbia.edu/services/advanced-tissue-pathology-and-imaging-core

Core that provides spectrum of advanced cellular and tissue pathology and imaging services for diabetes researchers at Columbia University. It also has microscopy equipment and services such as confocal, live 2-photon and scanning and transmission electron microscopy.

Proper citation: Columbia Diabetes Research Center Advanced Tissue Pathology and Imaging Core Facility (RRID:SCR_015085) Copy   


http://www.hopkinsmedicine.org/diabetes-research-center/research-cores/cell-biology.html

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 9,2024. Core that provides services in tissue analysis and imaging, islet biology, liver biology, and adipocyte biology. It includes the indepedent cores Derivation of IPSC and Bioenergetics as well as the Specialty Animal Surgery Subcore and Bone Biology Subcore.

Proper citation: Johns Hopkins University - University of Maryland Diabetes Research Center Cell Biology Core (RRID:SCR_015090) Copy   


http://www.hopkinsmedicine.org/diabetes-research-center/research-cores/healthcare-population.html

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 9,2024. Contains description of and contact information for multiple health and social science departments.

Proper citation: Johns Hopkins University - University of Maryland Diabetes Research Center Health and Populations Science Core (RRID:SCR_015093) Copy   


https://diabetescenters.org/cores/ucsd-ucla-genomics-and-epigenetics-core

Core which provides Diabetes Research Center investigators access to high-throughput sequencing, data acquisition and analysis. Its main services include Sample QC and Processing, Illumina Platform Library Preparation and Sequencing, and Expression microarrays (RNA, microRNA).

Proper citation: University of California San Diego - University of California Los Angeles Diabetes Research Center Genomics and Epigenetics Core Facility (RRID:SCR_015097) Copy   


https://diabetescenters.org/cores/ucsd-ucla-metabolic-and-molecular-physiology-core

Provides DRC investigators with thorough scientific consultation and timely, accurate, and easily accessible mouse, tissue, and cellular phenotyping. Services include whole animal, tissue and cellular metabolism, insulin action, and inflammatory signaling as well as cardiac, vascular and renal phenotyping associated with diabetes complications research. It also administers drugs and other substances to mice by different routes in a well-controlled setting.

Proper citation: University of California San Diego - University of California Los Angeles Diabetes Research Center Metabolic and Molecular Physiology Core Facility (RRID:SCR_015095) Copy   


http://digestivediseasescenters.org/content/ddrc-texas-medical-center-cellular-molecular-morphology-core

Core facility whose services include histology, immunohistochemistry, RNA in situ hybridization, mRNA probe generation, frozen sections for enzyme histochemistry, immunofluorescent antibody studies, live and fixed cell confocal, deconvolution microscopy and super resolution microscopy (SIM and STORM), and transmission electron microscopy, quantitative morphometric analysis, high throughput microscopy and high content analysis, laser capture microdissection for molecular genetic analyses, and digital images for internet communication and publication.

Proper citation: Texas Medical Center Digestive Diseases Center Cellular and Molecular Morphology Core (RRID:SCR_015219) Copy   


https://www.bcm.edu/research/centers/digestive-disease/core-facilities/study-design-and-clinical-research

Core that provides epidemiological and biostatistical support for design and analysis, and also provides investigators with access to the clinical specimens required for their basic and translational research activities. It offers assistance as well as didactic training in issues involving local and foreign IRB?s, HIPPA regulations, and importing or exporting clinical specimens.

Proper citation: Texas Medical Center Digestive Diseases Center Study Design and Clinical Research Core Services (RRID:SCR_015218) Copy   



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