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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://www.inbre.montana.edu/bioinformatics/functional_genomics/index.html
Core provides instrumentation and support for academic investigators throughout Montana and Rocky Mountain west. For most instrumentation, facility provides instruction and supervision followed by independent user access. For those doing Affymetrix microarrays, facility can also accept RNA samples and provides full service processing. Assists with experimental planning and grantmanship phases.
Proper citation: Montana State University Functional Genomics Core Facility (RRID:SCR_009939) Copy
https://github.com/YuningHao/FARDEEP
Software R tool for enumerating immune cell subsets from whole tumor tissue samples. Utilizes adaptive least trimmed square to automatically detect and remove outliers before estimating cell compositions.
Proper citation: FARDEEP (RRID:SCR_026704) Copy
https://github.com/DerrickWood/kraken2
Software tool as second version of Kraken taxonomic sequence classification system.
Proper citation: kraken2 (RRID:SCR_026838) Copy
https://github.com/KrishnaswamyLab/PHATE
Software tool for visualizing high dimensional data using novel conceptual framework for learning and visualizing manifold to preserve both local and global distances.
Proper citation: PHATE (RRID:SCR_027119) Copy
https://venomsbase-dashboard.shinyapps.io/VenomLanding/
Open-access, browser-based visualization and summary tool for venom transcriptomic and proteomic data. R Shiny–based interactive application designed as visualization and reporting interface for venom transcriptomic and proteomic data. It enables users to explore annotation metrics, toxin gene families, and quality-control summaries generated by analysis pipelines. While it will eventually serve as part of the VenomsBase front end, VenomView currently operates as standalone prototype. Provides interactive dashboards showing assembly quality, annotation scores, toxin gene families, and functional domains generated by the VenomFlow analysis pipeline. Connected to VenomLanding, VenomView currently features Doryteuthis pealeii (Squid), linking metadata with detailed annotation summaries. The expanded version will include Sepia bandensis (Cuttlefish), Octopus bimaculoides, and arachnid species.
Proper citation: VenomView (RRID:SCR_027588) Copy
https://github.com/nlm-irp-jianglab/SpikeHunter
Software deep learning tool for identifying phage tailspike proteins. Used to identify phage tailspike proteins.
Proper citation: SpikeHunter (RRID:SCR_024831) Copy
Open access knowledge base for microbial natural products discovery. Database of microbially derived natural product structures. Provides coverage of bacterial and fungal natural products to visualize chemical diversity. Includes compounds and contains referenced data for structure, compound names, source organisms, isolation references, total syntheses, and instances of structural reassignment. Interactive web portal permits searching by structure, substructure, and physical properties. Provides mechanisms for visualizing natural products chemical space and dashboards for displaying author and discovery timeline data. Atlas has been developed under FAIR principles.
Proper citation: Natural Products Atlas (RRID:SCR_025107) Copy
https://nationalmaglab.org/user-facilities/high-b-t-facility
Facility to conduct experiments in high magnetic fields up to 15 tesla and at very low temperatures down to 0.4 mK simultaneously. Located at University of Florida in Gainesville, it is operated as part of Physics Department Microkelvin Laboratory.
Proper citation: National High Magnetic Field Laboratory High B/T Core Facility (RRID:SCR_017360) Copy
Facility offers array of solid state, solution state, MRI/S (animal and human), MR microscopy and diffusion capabilities and techniques. Among their machines is 900 MHz 105 mm bore magnet. Techniques and instruments are available at two different MagLab facilities in Florida, NMR-MRI/S Facility at MagLab headquarters near Florida State University in Tallahassee and Advanced Magnetic Resonance Imaging and Spectroscopy Facility (AMRIS) housed within McKnight Brain Institute at University of Florida in Gainesville.
Proper citation: National High Magnetic Field Laboratory Advanced Magnetic Resonance Imaging and Spectroscopy Core Facility (RRID:SCR_017362) Copy
http://crl.berkeley.edu/molecular-imaging-center/
Microscopy core specializing in laser based fluorescence techniques. Offers training and expertise in 20 different microscope systems, including live cell and in vivo imaging, laser scanning (LSM) and spinning disk (SDC) confocal, multi-photon (2p), fluorescent lifetime imaging (FLIM), light-sheet microscopy (SPIM), super resolution (Airyscan), slide scanning and patterned illumination for optogenetic manipulation and readout. Provides offline computer analysis workstations for image processing, visualization and analysis, including GPU workstations. MIC operates in 3 different buildings on campus, with primary locations in Life Sciences Addition (LSA), North-side core in Barker Hall, and small outpost in Li Ka Shing Center for Biomedical and Health Sciences (LKS).Provides equipment in categories:Confocal and multi photon laser scanning microscopes,Spinning disk confocal microscopes,Lightsheet (SPIM) microscopes,Epifluorescence/widefield scopes and Computer workstations.
Proper citation: University of California at Berkeley Cancer Research Laboratory Molecular Imaging Center Core Facility (RRID:SCR_017852) Copy
http://bioimaging.dbi.udel.edu
Microscopy facility that houses equipment including confocal microscopes: LSM780 confocal microscope (Located at CBBI),LSM880 confocal microscope (Located at DBI 117),electron microscopes and their accessory instrumentation:Thermo Scientific Apreo VS SEM microscope,Hitachi S-4700, Leica EM ACE600 and Tousimis Autosamdri-815B,CX7 high content analysis system. Our staff has technical expertise across different microscopy platforms and methodologies.
Proper citation: University of Delaware BioImaging Center Core Facility (RRID:SCR_017814) Copy
http://www.udel.edu/chem/beebe/surface.htm
Core provides consulting and services in X-ray Photoelectron Spectroscopy (XPS or ESCA), Time-of-Flight Secondary-Ion Mass Spectrometry (TOF-SIMS), X-ray Photoelectron Imaging, Auger Electron Spectroscopy (AES), Scanning Auger Microscopy or Imaging (SAM), Secondary-Electron Microscopy (SEM), Ion-Scattering Spectroscopy (ISS or LEIS), Scanning Probe Microscopy (STM and AFM).
Proper citation: Delaware University Surface Analysis Core Facility (RRID:SCR_017796) Copy
https://www.mccormick.northwestern.edu/materials-science/clammp/
Core provides mechanical testing machines and accessories for conducting educational, research, and outreach experiments on most solid materials.
Proper citation: Northwestern University Central Laboratory for Materials Mechanical Properties Core Facility (RRID:SCR_017877) Copy
https://www.danforthcenter.org/our-work/core-facilities/advanced-bioimaging-laboratory/
Core provides instruments for live cell imaging including Leica SP8-X confocal microscope and other fluorescence microscopes. Facility provides workstation for confocal image processing, ancillary equipment required for transmission electron microscopy. Services are provided as self services after user training by IMF staff or as full services done by core facility staff.
Proper citation: Donald Danforth Plant Science Center Advanced Bioimaging Laboratory Core Facility (RRID:SCR_018951) Copy
https://www.colorado.edu/rc/resources/petalibrary
Provides service to support storage, archival, and sharing of research data. Available at subsidized cost to any researcher affiliated with University of Colorado Boulder.
Proper citation: University of Colorado Boulder High Performance Computing PetaLibrary Core Facility (RRID:SCR_019299) Copy
https://www.jmu.edu/microscopy/index.shtml
Core provides instrumentation, resources, training, and consultation. Facility offers access to diverse range of light microscope and imaging systems,image analysis software and solutions, practical and theoretical training for faculty, students and classes,consultation on data acquisition, analysis, and presentation.
Proper citation: James Madison University Light Microscopy and Imaging Core Facility (RRID:SCR_021904) Copy
Publicly accessible 3D data repository where subject experts, educators, and general public can find, view, interact with, and download 3D and 2D media representing physical objects important to the world’s natural history, cultural heritage, and scientific collections. Media data are contributed by a community that includes museums, institutions, researchers, scholars, and other subject experts who use MorphoSource to archive data, share findings, and increase scholarly impact. Contributed media represent both biological objects such as fossils and representatives of living species, as well as artifacts and objects created by humans that are critical to our shared cultural heritage.
Proper citation: MorphoSource (RRID:SCR_025654) Copy
https://github.com/zhouhj1994/LinDA
Software linear models for differential abundance analysis of microbiome compositional data. Used to tackle compositional effects in differential abundance analysis. It fits linear regression models on centered log2-ratio transformed data, identifies bias term due to transformation and compositional effect, and corrects bias using mode of regression coefficients. It could fit mixed-effect models.
Proper citation: LinDA (RRID:SCR_025966) Copy
https://github.com/kharchenkolab/conos
Software R package for joint analysis of multiple single-cell RNA-seq datasets. Used to wire together large collections of single-cell RNA-seq datasets, which allows for both identification of recurrent cell clusters and propagation of information between datasets in multi-sample or atlas-scale collections.
Proper citation: Conos (RRID:SCR_026381) Copy
https://github.com/compgenomics/MeTPeak
Software package for finding the location of m6A sites in MeRIP-seq data.
Proper citation: MeTPeak (RRID:SCR_026533) Copy
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