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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
zfishbook
 
Resource Report
Resource Website
1+ mentions
zfishbook (RRID:SCR_006896) zfishbook material resource, biomaterial supply resource Collection of revertible protein trap gene-breaking transposon (GBT) insertional mutants in zebrafish with active or cryopreserved lines from initially identified lines. Open to community-wide contributions including expression and functional annotation and represents world-wide central hub for information on how to obtain these lines from diverse members of International Zebrafish Protein Trap Consortium (IZPTC) and integration within other zebrafish community databases including Zebrafish Information Network (ZFIN), Ensembl and National Center for Biotechnology Information. Registration allows users to save their favorite lines for easy access, request lines from Mayo Clinic catalog, contribute to line annotation with appropriate credit, and puts them on optional mailing list for future zfishbook newletters and updates. gene-breaking transposon, expression-tagged, revertible mutation, gene, transposon, mutation, mutant, brain, muscle, skin, secretory, cardiac, brain line, muscle line, skin line, secretory line, cardiac line, plasmid, expression, functional annotation, gene-breaking transposon line, gene-break transposon mutagenesis, cell line, annotation, embryonic zebrafish, larval zebrafish, bio.tools is listed by: One Mind Biospecimen Bank Listing
is listed by: Debian
is listed by: bio.tools
is related to: Addgene
is related to: Zebrafish International Resource Center
has parent organization: Mayo Clinic Minnesota; Minnesota; USA
Mayo Clinic Cancer Center ;
Mayo Foundation ;
NIGMS GM63904;
NIDA DA14546;
NHGRI HG006431
PMID:22067444 Free, Freely available biotools:zfishbook, nlx_151613 https://bio.tools/zfishbook SCR_006896 book, z fish book, zfishbook, fish, z 2026-02-15 09:19:37 4
TheCellMap
 
Resource Report
Resource Website
10+ mentions
TheCellMap (RRID:SCR_018728) data or information resource, database, service resource Web accessible database for visualizing and mining global yeast genetic interaction network. Allows users to easily access, visualize, explore, and functionally annotate genetic interactions, or to extract and reorganize sub networks, using data driven network layouts in intuitive and interactive manner. Used for storing and visualizing genetic interactions in S. cerevisiae. Genetic interactions, genetic network, yeast genetics, synthetic genetic array, network visualization, annotation, data, genetic interaction visualization has parent organization: University of Toronto; Ontario; Canada NHGRI R01 HG005853;
NHGRI R01 HG005084;
Canadian Institutes of Health Research ;
NSF DBI 0953881
PMID:28325812 Free, Freely available SCR_018728 TheCellMap.org 2026-02-15 09:21:41 34
RegulomeDB
 
Resource Report
Resource Website
100+ mentions
RegulomeDB (RRID:SCR_017905) data or information resource, database, service resource Database that annotates SNPs with known and predicted regulatory elements in intergenic regions of H. sapiens genome. Known and predicted regulatory DNA elements include regions of DNAase hypersensitivity, binding sites of transcription factors, and promoter regions that have been biochemically characterized to regulation transcription. Source of these data include public datasets from GEO, ENCODE project, and published literature. Annotate, SNP, regulatory, DNA, element, intergenic, region, human, genome, sequence, DNAase, hypersensitivity, binding, site, transcription, factor, promoter, region, data, FASEB list NHGRI U54 HG 004558;
Beta Cell Consortium
PMID:22955989 Free, Freely available SCR_017905 2026-02-15 09:22:09 123
Hanalyzer
 
Resource Report
Resource Website
Hanalyzer (RRID:SCR_000923) software application, source code, software resource An open-source data integration system designed to assist biologists in explaining the results observed in genome-scale experiments as well as generating new hypotheses. It combines information extraction techniques, semantic data integration, and reasoning and facilitates network visualization. The Hanalyzer source code and binaries are available for download. genomic, visualization, reading, reasoning, reporting, throughput analyzer, data network has parent organization: University of Colorado Denver; Colorado; USA
has parent organization: SourceForge
NIDCR R01DE15191;
NLM R01LM008111;
NLM R01LM009254;
NIGMS R01GM083649;
NLM T15LM009451;
NHGRI 5R01HG004483-09
PMID:19325874 nlx_48287 SCR_000923 Hanalyzer: A 3R System 2026-02-15 09:18:01 0
PROVEAN
 
Resource Report
Resource Website
1000+ mentions
PROVEAN (RRID:SCR_002182) PROVEAN data analysis service, software resource, service resource, production service resource, analysis service resource A software tool which predicts whether an amino acid substitution or indel has an impact on the biological function of a protein. amino acid substitution, indel, function, protein, amino acid, substitution, protein variant, genome variant, next-generation sequencing, insertion, deletion is listed by: OMICtools
has parent organization: J. Craig Venter Institute
NIH ;
NHGRI 5R01HG004701-04
PMID:23056405 Free, Available for download, Freely available OMICS_01849 SCR_002182 Protein Variation Effect Analyzer 2026-02-15 09:18:15 2231
MEGA
 
Resource Report
Resource Website
1000+ mentions
MEGA (RRID:SCR_000667) MEGA, MEGA6, MEGA4, MEGA 4, MEGA 11 software application, sequence analysis software, data processing software, software resource, software toolkit, data analysis software Software integrated tool for conducting automatic and manual sequence alignment, inferring phylogenetic trees, mining web based databases, estimating rates of molecular evolution, and testing evolutionary hypotheses. Used for comparative analysis of DNA and protein sequences to infer molecular evolutionary patterns of genes, genomes, and species over time. MEGA version 4 expands on existing facilities for editing DNA sequence data from autosequencers, mining Web-databases, performing automatic and manual sequence alignment, analyzing sequence alignments to estimate evolutionary distances, inferring phylogenetic trees, and testing evolutionary hypotheses. MEGA version 6 enables inference of timetrees, as it implements RelTime method for estimating divergence times for all branching points in phylogeny. comparative, analysis, DNA, protein, sequence, molecular, evolution, pattern, gene, genome, evolution, FASEB list has parent organization: Pennsylvania State University Japan Society for the Promotion of Science ;
NHGRI HG006039;
NHGRI HG002096;
Burroughs-Wellcome Fund ;
NIGMS R01GM126567;
NSF ABI 1661218;
NIGMS R35GM139504
DOI:10.1093/molbev/msab120
PMID:24132122
PMID:31904846
PMID:22923298
PMID:21546353
PMID:17488738
PMID:15260895
PMID:11751241
PMID:8019868
Free, Available for download, Freely available SCR_023017, nlx_156838 https://www.megasoftware.net/mega4/ SCR_000667 MEGA11, Molecular Evolutionary Genetics Analysis, Molecular Evolutionary Genetics Analysis 6, Molecular Evolutionary Genetics Analysis 4 2026-02-15 09:17:58 2763
MouseCyc
 
Resource Report
Resource Website
1+ mentions
MouseCyc (RRID:SCR_001791) MouseCyc data analysis service, database, service resource, production service resource, data or information resource, analysis service resource A manually curated database of both known and predicted metabolic pathways for the laboratory mouse. It has been integrated with genetic and genomic data for the laboratory mouse available from the Mouse Genome Informatics database and with pathway data from other organisms, including human. The database records for 1,060 genes in Mouse Genome Informatics (MGI) are linked directly to 294 pathways with 1,790 compounds and 1,122 enzymatic reactions in MouseCyc. (Aug. 2013) BLAST and other tools are available. The initial focus for the development of MouseCyc is on metabolism and includes such cell level processes as biosynthesis, degradation, energy production, and detoxification. MouseCyc differs from existing pathway databases and software tools because of the extent to which the pathway information in MouseCyc is integrated with the wealth of biological knowledge for the laboratory mouse that is available from the Mouse Genome Informatics (MGI) database. energy production, biosynthesis, cell, cellular, degradation, detoxification, metabolism, mouse, physiological, enzymatic reaction, gene, disease, genome, metabolic pathway, pathway, compound, enzymatic reaction, protein, rna, reaction, blast, human, mammal, genetic, genomic is related to: Mouse Genome Informatics (MGI)
is related to: Gene Ontology
has parent organization: Jackson Laboratory
NHGRI HG003622 PMID:19682380 THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-10303 SCR_001791 MouseCyc database, Mouse Genome Informatics: MouseCyc database 2026-02-15 09:18:10 9
SPP
 
Resource Report
Resource Website
1+ mentions
SPP (RRID:SCR_001790) software application, data processing software, data analysis software, software resource R analysis and processing package for Illumina platform Chip-Seq data. chip seq data, illummina, r package, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
NHGRI U01HG004258;
NIGMS R01GM082798;
NCRR UL1RR024920
DOI:10.1038/nbt.1508 Free, Available for download, Freely available OMICS_00425, biotools:spp https://bio.tools/spp https://sites.google.com/a/brown.edu/bioinformatics-in-biomed/spp-r-from-chip-seq SCR_001790 SPP Package 2026-02-15 09:18:10 9
Bowtie 2
 
Resource Report
Resource Website
1000+ mentions
Bowtie 2 (RRID:SCR_016368) software application, sequence analysis software, data processing software, software resource, alignment software, image analysis software, data analysis software Ultrafast and memory efficient tool for aligning sequencing reads to long reference sequences. Supports gapped, local, and paired end alignment modes. More suited to finding longer, gapped alignments in comparison with original Bowtie method. sequence, analysis, long, reference, sequence, read, alignment, gap, local, pair, end, rna, rnaseq, bio.tools is used by: HLA-HD
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
is related to: Bowtie
NHGRI R01 HG006102;
NIGMS R01 GM083873
PMID:22388286 Free, Available for download, Freely available biotools:bowtie2 http://bowtie-bio.sourceforge.net/bowtie2/index.shtml
https://github.com/BenLangmead/bowtie2
https://bio.tools/bowtie2
SCR_016368 , bowtie 2, bowtie2 v 2.2.3 2026-02-15 09:20:59 1745
PanoramaWeb
 
Resource Report
Resource Website
PanoramaWeb (RRID:SCR_017136) software resource, data access protocol, web service, service resource, storage service resource, data repository, data or information resource Repository software for targeted mass spectrometry assays from Skyline. Targeted proteomics knowledge base. Public repository for quantitative data sets processed in Skyline. Facilitates viewing, sharing, and disseminating results contained in Skyline documents. repository, software, targeted, mass, spectrometry, data, proteomic, quantitative, viewing, sharing, disseminating, result, , bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: University of Washington; Seattle; USA
works with: Skyline
NIGMS R01 GM103551;
NIGMS R01 GM121696;
NHGRI U54 HG008097;
NIH R01 AR071762;
University of Washington Proteomics Resource
DOI:10.1074/mcp.RA117.000543 Free, Freely available biotools:panorama https://bio.tools/panorama SCR_017136 2026-02-15 09:21:58 0
proMODMatcher
 
Resource Report
Resource Website
1+ mentions
proMODMatcher (RRID:SCR_017219) software application, data processing software, data analysis software, software resource Software tool as probabilistic multi omics data matching procedure to curate data, identify and correct data annotation and errors in large databases. Used to check potential labeling errors in profiles where number of cis relationships is small, such as miRNA and RPPA profiles. probabilistic, matching, curate, omic, data, identify, correct, error, large, database, analysis, sample, label, bio.tools is listed by: bio.tools
is listed by: Debian
is related to: Icahn School of Medicine at Mount Sinai; New York; USA
NHGRI U01 HG008451;
NIA R01 AG046170;
NIAID U19 AI118610
biotools:modmatcher https://bio.tools/modmatcher SCR_017219 probabilisticMulti Omics DataMatcher 2026-02-15 09:21:59 1
Juicer
 
Resource Report
Resource Website
100+ mentions
Juicer (RRID:SCR_017226) software application, data processing software, data analysis software, software resource Software platform for analyzing kilobase resolution Hi-C data. Open source tool for analyzing terabase scale Hi-C datasets. Allowes to transform raw sequence data into normalized contact maps. analysis, kilobase, resolution, Hi-C, data, terabase, dataset, transform, raw, sequence, normalized, contact, map has parent organization: Baylor College of Medicine; Houston; Texas NIH Office of the Director DP2 OD008540;
NHLBI U01 HL130010;
NSF PHY-1427654;
NHGRI HG006193;
Welch Foundation ;
Cancer Prevention Research Institute of Texas ;
NVIDIA Research Center Award ;
IBM University Challenge Award ;
Google Research Award ;
McNair Medical Institute Scholar Award ;
President Early Career Award in Science and Engineering ;
NHGRI HG003067;
PD Soros Fellowship
PMID:27467249 Free, Available for download, Freely available SCR_017226 2026-02-15 09:21:59 108
PathwayNet
 
Resource Report
Resource Website
1+ mentions
PathwayNet (RRID:SCR_017353) data analysis service, software resource, data access protocol, web service, service resource, production service resource, analysis service resource Web user interface for interaction predictions of human gene networks and integrative analysis of user data types that takes advantage of data from diverse tissue and cell-lineage origins. Predicts presence of functional association and interaction type among human genes or its protein products on whole genome scale. Used to analyze experimetnal gene in context of interaction networks. Interface, interaction, predict, human, gene, network, integrative, analysis, user, data, tissue, cell, functional, protein, genome is listed by: OMICtools
has parent organization: Princeton University; New Jersey; USA
NIGMS R01 GM071966;
NHGRI HG005998;
NIGMS P50 GM071508
PMID:25431329 Free, Freely available SCR_017353 2026-02-15 09:22:03 7
peddy
 
Resource Report
Resource Website
10+ mentions
peddy (RRID:SCR_017287) software application, data processing software, software resource, data analytics software, data analysis software Software package that evaluates correspondence between stated sexes, relationships, and ancestries in pedigree file and those inferred from genotypes in VCF file resulting from human whole genome sequencing or whole exome sequencing studies. Facilitates both automated and interactive, visual detection of sample swaps, poor sequencing quality, and other indicators of sample problems. sex, relation, ancestry, evaluate, pedigree, VCF file, genome, sequencing, exome, error, genotype has parent organization: University of Utah; Utah; USA NHGRI R01 HG006693 PMID:28190455 Free, Available for download, Freely available http://quinlanlab.org/#portfolioModal8 SCR_017287 2026-02-15 09:22:00 10
GeneMarkS-T
 
Resource Report
Resource Website
100+ mentions
GeneMarkS-T (RRID:SCR_017648) software application, data processing software, data analysis software, software resource Software package for ab initio identification of protein coding regions in RNA transcripts. Algorithm parameters are estimated by unsupervised training which makes unnecessary manually curated preparation of training sets. Sets of assembled eukaryotic transcripts can be analyzed by modified GeneMarkS-T algorithm which part of gene prediction programs GeneMark. Identification, protein, coding, region, RNA, transcript, gene, discovery, eukaryotic, sequence, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: Georgia Institute of Technology; Georgia; USA
NHGRI HG000783 PMID:25870408 Restricted biotools:GeneMarkS-t https://bio.tools/GeneMarkS-T SCR_017648 2026-02-15 09:22:06 113
Computing Genome Assembly Likelihoods
 
Resource Report
Resource Website
100+ mentions
Computing Genome Assembly Likelihoods (RRID:SCR_017624) CGAL software application, data processing software, software resource, alignment software, image analysis software Software tool for computing genome assembly likelihoods.Computes likelihood of reads with respect to assembly and statistical model which can be used as metric for evaluating assemblies. Novel likelihood based approach to assembly assessment in absence of ground truth. Computing, genome, assembly, likelihood, read, evaluation NHGRI R21 HG006583;
Fulbright Science & Technology Fellowship
PMID:23360652 http://bio.math.berkeley.edu/cgal/ SCR_017624 2026-02-15 09:22:04 106
FastProject
 
Resource Report
Resource Website
FastProject (RRID:SCR_017462) software application, data visualization software, data processing software, software resource, data analysis software Software Python tool for low dimensional analysis of single-cell RNA-Seq data. Software package for two dimensional visualization of single cell data. Analyzes gene expression matrix and produces output report in which two-dimensional of data can be explored. Two, dimensional, data, reduction, single, cell, RNA seq, visualization, gene, expression, matrix, report, explore, BRAIN Initiative, bio.tools is recommended by: BRAIN Initiative
is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: University of California at Berkeley; Berkeley; USA
National Institutes of Health NRSA Trainee appointment ;
California Research Alliance by BASF ;
NIMH U01 MH105979;
NHGRI U01 HG007910
PMID:27553427 Free, Available for download, Freely available biotools:fastproject https://bio.tools/fastproject SCR_017462 2026-02-15 09:22:02 0
GO Gene Ontology Consortium and Knowledgebase
 
Resource Report
Resource Website
1+ mentions
GO Gene Ontology Consortium and Knowledgebase (RRID:SCR_017505) GOC organization portal, data or information resource, consortium, portal Consortium integrates resources from variety of research groups, from model organisms to protein databases to biological research communities actively involved in development and implementation of Gene Ontology. Mission to develop up to date, comprehensive, computational model of biological systems, from molecular level to larger pathways, cellular and organism level systems. Integrate, resource, model, organism, protein, database, gene, ontology, develope, cellular, system NHGRI HG002273;
NHGRI U24 HG012212
SCR_017505 GO Consortium, Gene Ontology Consortium 2026-02-15 09:21:21 8
Michigan Imputation Server
 
Resource Report
Resource Website
100+ mentions
Michigan Imputation Server (RRID:SCR_017579) web service, data access protocol, service resource, software resource Web server to implement whole genotype imputation workflow for efficient parallelization of computationally intensive tasks. Service for imputation that facilitates access to new reference panels and greatly improves user experience and productivity. Used to find haplotype segments and reference panel of sequenced genomes, assign genotypes at untyped markers, improve genome coverage, facilitate comparison and combination of studies that use different marker panels, increase power to detect genetic association, and guide fine mapping. Whole, genotype, imputation, workflow, parallelization, task, find, haplotype, segment, reference, panel, sequence, genome, mapping has parent organization: University of Michigan; Ann Arbor; USA NHGRI HG007022;
NHLBI HL117626;
NHGRI HG000376;
NIDA R01 DA037904;
Austrian Science Fund ;
European Community Seventh Framework Programme ;
NIA
PMID:27571263 Restricted https://github.com/genepi/imputationserver SCR_017579 Next Generation Genotype Imputation Service 2026-02-15 09:22:05 156
ProtParam Tool
 
Resource Report
Resource Website
5000+ mentions
ProtParam Tool (RRID:SCR_018087) software application, sequence analysis software, data processing software, software resource, service resource, production service resource, analysis service resource, data analysis software Software tool to calculate various physicochemical parameters for given protein stored in Swiss-Prot or TrEMBL or for user entered protein sequence. Protein can either be pecified as Swiss-Prot/TrEMBL accession number or ID, or in form of raw sequence. Computed parameters include molecular weight, theoretical pI, amino acid composition, atomic composition, extinction coefficient, estimated half-life, instability index, aliphatic index and grand average of hydropathicity. Calculate phycicochemical parameter, protein, Swiss-Prot, TrEMBL, protein sequence, molecular weight, theortical pl, amino acid composition, atomic composition, extinction coefficient, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: ExPASy Bioinformatics Resource Portal
NHGRI U01 HG02712;
Swiss Federal Government through Federal Office of Education and Science
PMID:10027275 Free, Freely available biotools:protparam https://bio.tools/protparam SCR_018087 ProtParam 2026-02-15 09:22:10 5406

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