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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
cBioPortal
 
Resource Report
Resource Website
5000+ mentions
cBioPortal (RRID:SCR_014555) data or information resource, database, portal A portal that provides visualization, analysis and download of large-scale cancer genomics data sets. cancer, genomics, database, portal, data sets, FASEB list is used by: NaviCom NCI U24CA143840;
NCRR RR031228-02
PMID:23550210
PMID:22588877
Please cite, Software is available via GitHub, Open source https://github.com/cBioPortal/cbioportal/ https://github.com/cBioPortal/cbioportal/blob/master/docs/README.md SCR_014555 cBioPortal for Cancer Genomics 2026-02-15 09:21:04 8539
liftOver
 
Resource Report
Resource Website
500+ mentions
liftOver (RRID:SCR_018160) software application, service resource, data processing software, software resource Web tool to convert genome coordinates and genome annotation files between assemblies. Used to translate genomic coordinates from one assembly version into another and retrieves putative orthologous regions in other species using UCSC chained and netted alignments. Convert genome coordinate, genome annotation file, translate genomic coordinate, assembly version, retrieve orthologous region is related to: UCSC Genome Browser
has parent organization: University of California at Santa Cruz; California; USA
NHGRI ;
Howard Hughes Medical Institute ;
NCI
DOI:10.1093/nar/gkj144 Free, Available for download, Freely available SCR_018160 2026-02-15 09:22:11 762
GeoDa
 
Resource Report
Resource Website
100+ mentions
GeoDa (RRID:SCR_018559) software application, data visualization software, data processing software, software resource, data analysis software Software program for spatial analysis for non geographic information systems specialists. Includes functionality ranging from simple mapping to exploratory data analysis, visualization of global and local spatial autocorrelation, and spatial regression. Spatial analysis, data analysis, spatial autocorrelation visualization, spatial regression, mapping NSF BCS 9978058;
NCI R01 CA95949
DOI:10.1111/j.0016-7363.2005.00671.x Free, Freely available SCR_018559 2026-02-15 09:21:39 192
FairSubset
 
Resource Report
Resource Website
FairSubset (RRID:SCR_019102) web service, data access protocol, software resource Web tool to choose representative subsets of data for use with replicates or groups of different sample sizes. Used to retain distribution information at single datum level and may be considered for standardized use in fair publishing practices. Representative data subsets, different sample sizes groups, different sample sizes replicates, retaining distribution information, fair publishing NCI CA207729;
Polish government grant
PMID:31583263 Free, Freely available SCR_019102 2026-02-15 09:22:19 0
GSVA
 
Resource Report
Resource Website
100+ mentions
GSVA (RRID:SCR_021058) GSVA software application, data processing software, software resource, software toolkit, data analysis software Open source software R package for assaying variation of gene set enrichment over sample population.Used for microarray and RNA-seq data analysis. Gene set enrichment method that estimates variation of pathway activity over sample population in unsupervised manner. Gene set enrichment, variation estimation, pathway activity, sample population, microarray, RNA-seq, data analysis is listed by: Bioconductor ISCIII COMBIOMED ;
Spanish MINECO ;
NCI U54 CA149237
PMID:23323831 Free, Available for download, Freely available SCR_021058 Gene Set Variation Analysis 2026-02-15 09:22:31 256
CyLinter
 
Resource Report
Resource Website
1+ mentions
CyLinter (RRID:SCR_021157) software application, data processing software, software resource, segmentation software, image analysis software Open source software tool as interactive image segmentation filter for multiplex microscopy that aids in identification and removal of cell segmentation instances corrupted by optical and image processing artifacts. multiplex microscopy, quality control, single-cell data, Interactive Image Segmentation Filter NCI U2C CA233262;
NCI U54 CA225088
Free, Available for download, Freely available SCR_021157 2026-02-15 09:22:26 3
ArchR
 
Resource Report
Resource Website
100+ mentions
ArchR (RRID:SCR_020982) software application, data processing software, software resource, software toolkit, data analysis software Software R package for processing and analyzing single-cell ATAC-seq data. Used for integrative single cell chromatin accessibility analysis.Provides intuitive, user focused interface for complex single cell analysis, including doublet removal, single cell clustering and cell type identification, unified peak set generation, cellular trajectory identification, DNA element-to-gene linkage, transcription factor footprinting, mRNA expression level prediction from chromatin accessibility and multi-omic integration with single-cell RNA sequencing. single-cell ATAC-seq data analysis, single-cell ATAC-seq data processing, single cell chromatin accessibility analysis, doublet removal, single cell clustering, cell type identification, unified peak set generation, cellular trajectory identification, transcription factor footprinting NHGRI RM1 HG007735;
NHGRI UM1 HG009442;
NCI R35 CA209919;
NHGRI UM1 HG009436;
NCI U2C CA233311;
NIAID U19 AI057266;
NIA K99 AG059918;
American Society of Hematology Scholar Award ;
International Collaborative Award ;
Defense Advanced Research Project Agency ;
Ray and Dagmar Dolby Family Fund ;
Stanford Cancer Institute-Goldman Sachs Foundation Cancer Research Award
PMID:33633365 Free, Available for download, Freely available https://github.com/GreenleafLab/ArchR
https://www.archrproject.com/
https://github.com/GreenleafLab/ArchR_2020
SCR_020982 2026-02-15 09:22:24 358
MCMICRO
 
Resource Report
Resource Website
10+ mentions
MCMICRO (RRID:SCR_021048) software application, image processing software, data processing software, software resource Open source software tool as multiple choice microscopy pipeline for multiplexed whole slide imaging and tissue microarrays. Scalable, modular image processing pipeline for multiplexed tissue imaging. Used for performing sequential steps needed to transform large, multi channel whole slide images into single cell data. NCI U54 CA225088;
Harvard Medical School ;
Ludwig Cancer Research Foundation ;
University of Zurich BioEntrepreneur Fellowship ;
Swiss National Science Foundation Early Postdoc Mobility fellowship
DOI:10.1101/2021.03.15.435473 Free, Available for download, Freely available https://github.com/labsyspharm/mcmicro SCR_021048 2026-02-15 09:22:24 11
StringTie
 
Resource Report
Resource Website
1000+ mentions
StringTie (RRID:SCR_016323) software application, sequence analysis software, data processing software, software resource, data analysis software Software application for assembling of RNA-Seq alignments into potential transcripts. It enables improved reconstruction of a transcriptome from RNA-seq reads. This transcript assembling and quantification program is implemented in C++ . assembling, RNA, sequence, transcript, gene, alignment, reconstruction, read, analysis, process, bio.tools is listed by: bio.tools
is listed by: Debian
is listed by: OMICtools
the Cancer Prevention and Research Institute of Texas ;
NHGRI R01 HG006677;
NIGMS R01 GM105705;
NHGRI R01 HG006102;
NCI R01 CA120185;
NCI R01 CA134292
PMID:25690850
DOI:10.1038/nbt.3122
Open source, Free, Freely available, Available for download biotools:stringtie, OMICS_07226 https://github.com/gpertea/stringtie
https://bio.tools/stringtie
https://sources.debian.org/src/stringtie/
SCR_016323 2026-02-15 09:21:38 4072
DESeq2
 
Resource Report
Resource Website
10000+ mentions
DESeq2 (RRID:SCR_015687) software tool, software application, data processing software, software resource, data analysis software Software package for differential gene expression analysis based on the negative binomial distribution. Used for analyzing RNA-seq data for differential analysis of count data, using shrinkage estimation for dispersions and fold changes to improve stability and interpretability of estimates. differential, gene, expression, analysis, binominal, distribution, RNA-seq data, Bioconductor, bio.tools is used by: Glimma
is used by: TEtranscripts
is listed by: Bioconductor
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
is related to: SARTools
works with: tximport
International Max Planck Research School for Computational Biology and Scientific Computing ;
NCI T32 CA009337;
European Union’s 7th Framework Programme
Free, Available for download, Freely available biotools:deseq2 https://github.com/mikelove/DESeq2
https://bio.tools/deseq2
SCR_015687 2026-02-15 09:21:36 43994
Differential Gene Correlation Analysis
 
Resource Report
Resource Website
1+ mentions
Differential Gene Correlation Analysis (RRID:SCR_020964) DGCA software application, data processing software, data analysis software, software resource Software R package to perform differential gene correlation analysis. Performs differential correlation analysis on input matrices, with multiple conditions specified by design matrix. Differential gene, gene, gene correlation, correlation analysis, input matrices, differential correlations, identifier pairs, gene expression data, calculate differential correlations is listed by: CRAN NIA F30 AG052261;
NIA R01 AG046170;
NCI R01 CA163772;
NIAID U01 AI111598
PMID:27846853 Free, Available for download, Freely available https://github.com/andymckenzie/DGCA SCR_020964 2026-02-15 09:22:30 1
Markov Affinity based Graph Imputation of Cells
 
Resource Report
Resource Website
50+ mentions
Markov Affinity based Graph Imputation of Cells (RRID:SCR_022371) MAGIC software application, data processing software, data analysis software, software resource Software tool for imputing missing values restoring structure of large biological datasets.Method that shares information across similar cells, via data diffusion, to denoise cell count matrix and fill in missing transcripts. imputing missing values, restoring structure, shares information across similar cells, denoise cell count matrix, fill in missing transcripts NICHD DP1 HD084071;
NCI R01 CA164729;
NCI P30 CA008748;
American Cancer Society ;
Simons SFARI grants
PMID:29961576 Free, Available for download, Freely available SCR_022371 2026-02-15 09:22:52 83
Minimum Information about Tissue Imaging
 
Resource Report
Resource Website
Minimum Information about Tissue Imaging (RRID:SCR_022830) MITI organization portal, portal, consortium, data or information resource, narrative resource, standard specification Consortium provides guidelines for highly multiplexed tissue images. Standard that applies best practices developed for genomics and other microscopy data to highly multiplexed tissue images and traditional histology. Data and metadata standards consistent with Findable, Accessible, Interoperable, and Reusable (FAIR) standards that guide data deposition, curation and release. Data and metadata standards, FAIR, tissue imaging, minimum information standard, guidelines for highly multiplexed tissue images NCI U2C CA233262;
NCI U54 CA225088;
NCI U2C CA233280;
NCI U2C CA233195;
NCI U2C CA233291;
NCI U2C CA233311;
NCI U2C CA233238;
NCI U2C CA233285;
NCI U2C CA233303;
NCI U2C CA233284;
NCI U2C CA233254
PMID:35277708 Free, Freely available https://github.com/miti-consortium/MITI SCR_022830 MITI Consortium 2026-02-15 09:22:20 0
miQC
 
Resource Report
Resource Website
1+ mentions
miQC (RRID:SCR_022697) software application, data processing software, data analysis software, software resource Software tool as flexible, probablistic metrics for quality control of scRNA-seq data. Adaptive probabilistic framework for quality control of single-cell RNA-sequencing data. Data driven QC metric that jointly models proportion of reads mapping to mtDNA and number of detected genes with mixture models in probabilistic framework to predict which cells are low quality in given dataset. scRNA-seq data quality control, QC metric, low quality data prediction, single cell RNA-sequencing data NCI CA237170;
NHGRI HG009007;
European Union Horizon 2020 research and innovation program ;
Academy of Finland ;
Cancer Foundation Finland
PMID:34428202 Free, Available for download, Freely available SCR_022697 2026-02-15 09:22:56 2
Stitchr
 
Resource Report
Resource Website
1+ mentions
Stitchr (RRID:SCR_022139) software application, sequence analysis software, data processing software, software resource, data analysis software Software Python tool for stitching coding T cell receptors nucleotide sequences from V,J,CDR3 information. Produces complete coding sequences representing fully spliced TCR cDNA given minimal V,J,CDR3 information. Stitch together coding TCR nucleotide sequences, Python, T cell receptors nucleotide, V and J gene symbols, hypervariable CDR3 amino acid sequence, fully spliced TCR cDNA NCI R01 CA164273;
NIAID R43 AI120313;
NCI R43 CA232942;
Emily Venanzi Fund
PMID:35325179 Free, Available for download, Freely available SCR_022139 2026-02-15 09:22:12 3
Physician Data Query
 
Resource Report
Resource Website
1+ mentions
Physician Data Query (RRID:SCR_006833) PDQ clinical trial, database, ontology, people resource, registry, data or information resource, controlled vocabulary NCI''s comprehensive cancer database that contains summaries on a wide range of cancer topics; a registry of 8,000+ open and 19,000+ closed cancer clinical trials from around the world; a directory of professionals who provide genetics services; the NCI Dictionary of Cancer Terms, with definitions for 6,800+ cancer and medical terms; and the NCI Drug Dictionary, which has information on 2,300+ agents used in the treatment of cancer or cancer-related conditions. The PDQ cancer information summaries are peer reviewed and updated monthly by six editorial boards comprised of specialists in adult treatment, pediatric treatment, supportive care, screening and prevention, genetics, and complementary and alternative medicine. The Boards review current literature from more than 70 biomedical journals, evaluate its relevance, and synthesize it into clear summaries. Many of the summaries are also available in Spanish. adult, pediatric, child, alternative, breast, clinical trial, colorectal, hypercalcemia, legal, lung, medicine, medullary, nausea, ovarian, pain, pathophysiology, pediatric, pharmaceutical, physician, prevention, prognosis, prostate, psychosocial, query, risk factor, screening, social, syndrome, thyroid, treatment, umls, genetics, medical, drug, peer review is listed by: BioPortal
has parent organization: National Cancer Institute
Cancer, Cancer-related condition NCI nif-0000-21318 SCR_006833 PDQ - NCI''s Comprehensive Cancer Database 2026-02-15 09:19:20 2
Synapse
 
Resource Report
Resource Website
1000+ mentions
Synapse (RRID:SCR_006307) Synapse database, service resource, storage service resource, data repository, data or information resource A cloud-based collaborative platform which co-locates data, code, and computing resources for analyzing genome-scale data and seamlessly integrates these services allowing scientists to share and analyze data together. Synapse consists of a web portal integrated with the R/Bioconductor statistical package and will be integrated with additional tools. The web portal is organized around the concept of a Project which is an environment where you can interact, share data, and analysis methods with a specific group of users or broadly across open collaborations. Projects provide an organizational structure to interact with data, code and analyses, and to track data provenance. A project can be created by anyone with a Synapse account and can be shared among all Synapse users or restricted to a specific team. Public data projects include the Synapse Commons Repository (SCR) (syn150935) and the metaGenomics project (syn275039). The SCR provides access to raw data and phenotypic information for publicly available genomic data sets, such as GEO and TCGA. The metaGenomics project provides standardized preprocessed data and precomputed analysis of the public SCR data. data sharing, collaboration, data management, analysis, genome, phenotype, crowd sourcing, open data, provenance, resource management, annotation, authoring, markup, r, python, java, command-line, cloud, FASEB list is used by: NF Data Portal
is listed by: FORCE11
is listed by: DataCite
is listed by: re3data.org
is related to: clearScience
is related to: Exemplar Microscopy Images of Tissues
has parent organization: Sage Bionetworks
Cancer, Normal, Cardiovascular disease, Floppy hat syndrome Life Sciences Discovery Fund ;
NCI ;
NHLBI ;
Alfred P. Sloan Foundation
The community can contribute to this resource nlx_151983, DOI:10.17616/R3B934, r3d100011894, DOI:10.7303 https://doi.org/10.17616/R3B934
https://doi.org/10.48550/arxiv.1506.00272
https://doi.org/10.7303/
https://dx.doi.org/10.7303
https://doi.org/10.17616/R3B934
SCR_006307 2026-02-15 09:19:12 1002
Geneshot
 
Resource Report
Resource Website
1+ mentions
Geneshot (RRID:SCR_017582) web service, data access protocol, software resource Software tool as search engine for ranking genes from arbitrary text queries. Enables to enter arbitrary search terms, to receive ranked lists of genes relevant to search terms. Returned ranked gene lists contain genes that were previously published in association with search terms, as well as genes predicted to be associated with terms based on data integration from multiple sources. Search results are presented with interactive visualizations. Ranking, gene, arbitrary, text, query, list, predict, association, data, integration, interactive, visualization, bio.tools is listed by: Debian
is listed by: bio.tools
NHLBI U54 HL127624;
NCI U24 CA224260;
NIGMS T32 GM062754;
NIH Office of the Director OT3OD025467
PMID:31114885 Free, Freely available biotools:Geneshot https://bio.tools/Geneshot SCR_017582 2026-02-15 09:22:09 4
Structure Harvester
 
Resource Report
Resource Website
100+ mentions
Structure Harvester (RRID:SCR_017636) software resource, data access protocol, web service, service resource, production service resource, analysis service resource Web based program for collating results generated by program STRUCTURE. Provides assess and visualize likelihood values across multiple values of K and hundreds of iterations for easier detection of number of genetic groups that best fit data. Reformats data for use in downstream programs, such as CLUMPP.It is complement for using software Structure in genetics population. Website and program for visualizing STRUCTURE output and implementing Evanno method., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. Visualizing, STRUCTURE, Evanno, method, collating, result, detection, genetic, group, fit, data, reformat is related to: University of California at Santa Cruz; California; USA
is related to: University of California at Irvine; California; USA
is related to: University of California at Los Angeles; California; USA
works with: STRUCTURE
NCI U24 CA143858;
NCI R21 CA135937
DOI:10.1007/s12686-011-9548-7 THIS RESOURCE IS NO LONGER IN SERVICE SCR_017636 StructureHarvester 2026-02-15 09:22:05 297
Interactive Line Graph
 
Resource Report
Resource Website
Interactive Line Graph (RRID:SCR_018334) data analysis service, software resource, data access protocol, web service, service resource, production service resource, analysis service resource Interactive web based tool for creating line graphs for scientific publications. Users can view different summary statistics, examine lines for any individual in data, focus on time points or groups of interest, and view changes between any two time points and conditions. Line graph, scientific publication, summary statistics, examine lines, time point, changes between time points, data, statistic, plot NCI P50 AG44170;
Office of Research on Women Health
PMID:27332507 Free, Freely available SCR_018334 2026-02-15 09:22:20 0

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