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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Website Status Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
TETRA
 
Resource Report
Resource Website
50+ mentions
TETRA (RRID:SCR_004573) TETRA software resource Standalone software programs that can be used to calculate how well tetranucleotide usage patterns in DNA sequences correlate. Such correlations can provide valuable hints on the relatedness of DNA sequences. tetranucleotide, dna sequence is listed by: OMICtools
has parent organization: Max Planck Institute for Marine Microbiology; Bremen; Germany
PMID:15305919
PMID:15507136
OMICS_01474 SCR_004573 TETRA - Fragment assignment by intrinsic tetranucleotide frequencies 2026-02-07 02:06:49 66
BioPig
 
Resource Report
Resource Website
1+ mentions
BioPig (RRID:SCR_004636) BioPig software resource Software providing a framework for genomic data analysis using Apache Pig and Hadoop. mapreduce/hadoop, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Lawrence Berkeley National Laboratory
PMID:24021384 biotools:biopig, OMICS_01225 https://bio.tools/biopig SCR_004636 2026-02-07 02:06:25 2
Nonpareil
 
Resource Report
Resource Website
50+ mentions
Nonpareil (RRID:SCR_004629) Nonpareil software resource Estimate average coverage and create Nonpareil curves for metagenomic datasets. is listed by: OMICtools PMID:24123672 OMICS_01419 SCR_004629 2026-02-07 02:06:50 78
AbundanceBin
 
Resource Report
Resource Website
1+ mentions
AbundanceBin (RRID:SCR_004648) AbundanceBin software resource An abundance-based software tool for binning metagenomic sequences, such that the reads classified in a bin belong to species of identical or very similar abundances. AbundanceBin also gives estimations of species abundances and their genome sizes -two important characteristic parameters for a microbial community. metagenome, sequence is listed by: OMICtools
has parent organization: Indiana University; Indiana; USA
PMID:21385052 Acknowledgement requested, Free, Public OMICS_01471 SCR_004648 2026-02-07 02:06:25 6
VariationHunter
 
Resource Report
Resource Website
10+ mentions
VariationHunter (RRID:SCR_004865) VariationHunter software resource A software tool for discovery of structural variation in one or more individuals simultaneously using high throughput technologies. structural variation, genome, next-generation sequencing is listed by: OMICtools
is related to: SPLITREAD
has parent organization: Simon Fraser University; British Columbia; Canada
has parent organization: SourceForge
PMID:22048523
PMID:20529927
OMICS_00328 SCR_004865 VariationHunter-CommonLaw 2026-02-07 02:06:33 12
Phymm and PhymmBL
 
Resource Report
Resource Website
10+ mentions
Phymm and PhymmBL (RRID:SCR_004751) Phymm, PhymmBL software resource Software for Phylogenetic Classification of Metagenomic Data with Interpolated Markov Models to taxonomically classify DNA sequences and accurately classify reads as short as 100 bp. PhymmBL, the hybrid classifier included in this distribution which combines analysis from both Phymm and BLAST, produces even higher accuracy. metagenome, sequence, taxonomy, classification, phylogenetic classification, genome, short read is listed by: OMICtools
has parent organization: University of Maryland; Maryland; USA
NLM R01-LM006845 PMID:19648916
PMID:21527926
Open-source license OMICS_01461 SCR_004751 2026-02-07 02:06:53 12
deStruct
 
Resource Report
Resource Website
1+ mentions
deStruct (RRID:SCR_004747) deStruct software resource A software tool for identifying structural variation in tumour genomes from whole genome illumina sequencing. structural variation, genome, genomics is listed by: OMICtools
has parent organization: Google Code
Tumor, Cancer Open unspecified license OMICS_00314 SCR_004747 deStruct - Bioinformatics tool for identifying structural variation in tumour genomes 2026-02-07 02:06:53 7
ALDEx2
 
Resource Report
Resource Website
100+ mentions
ALDEx2 (RRID:SCR_003364) software resource Software tool to examine compositional high-throughput sequence data with Welch's t-test. A differential relative count abundance analysis for the comparison of two conditions. For example, single-organism and meta-rna-seq high-throughput sequencing assays, or of selected and unselected values from in-vitro sequence selections. Uses a Dirichlet-multinomial model to infer abundance from counts, that has been optimized for three or more experimental replicates. Infers sampling variation and calculates the expected Benjamini-Hochberg false discovery rate given the biological and sampling variation using several parametric and non-parametric tests. Can to glm and Kruskal-Wallace tests on one-way ANOVA style designs. standalone software, r, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: aldex
has parent organization: Western University; Ontario; Canada
PMID:24910773 Free, Available for download, Freely available biotools:aldex2, OMICS_04634 https://bio.tools/aldex2 SCR_003364 2026-02-07 02:06:00 492
RCircos
 
Resource Report
Resource Website
100+ mentions
RCircos (RRID:SCR_003310) software resource Software package that provides a simple and flexible way to generate Circos 2D track plot images for genomic data visualization. The types of plots include: heatmap, histogram, lines, scatterplot, tiles and plot items for further decorations include connector, link (lines and ribbons), and text (gene) label. All functions require only R graphics package that comes with R base installation. standalone software, unix/linux, mac os x, windows, r is listed by: OMICtools
is related to: shinyCircoss
has parent organization: CRAN
has parent organization: Bitbucket
PMID:23937229 Free, Available for download, Freely available OMICS_04661 https://bitbucket.org/henryhzhang/rcircos/ SCR_003310 RCircos: Circos 2D Track Plot 2026-02-07 02:06:16 229
JCVI Primer Designer
 
Resource Report
Resource Website
1+ mentions
JCVI Primer Designer (RRID:SCR_003275) JCVI Primer Designer software resource High throughput PCR primer design software. Target regions defined through a rich set of descriptors, such as Ensembl accessions and arbitrary genomic coordinates, may be specified. Primer pairs are then selected computationally to produce a minimal amplicon set capable of tiling across the specified target regions. As part of the tiling process, primer pairs are computationally screened to meet the criteria for success with one of two PCR amplification protocols. perl, command-line, pcr primer design, pcr, primer, high throughput sequencing is listed by: OMICtools
has parent organization: SourceForge
PMID:18405373 Free, Available for download, Freely available OMICS_02330 SCR_003275 2026-02-07 02:05:59 1
ddCt
 
Resource Report
Resource Website
100+ mentions
ddCt (RRID:SCR_003396) ddCt software resource Software package providing an approximation method to determine relative gene expression with quantitative real-time PCR (qRT-PCR) experiments. It requires no standard curve for each primer-target pair, therefore reducing the working load and yet returning accurate enough results as long as the assumptions of the amplification efficiency hold. The package implements a pipeline to collect, analyze and visualize qRT-PCR results, for example those from TaqMan SDM software, mainly using the ddCt method. The pipeline can be either invoked by a script in command-line or through the API consisting of S4-Classes, methods and functions. differential expression, gene expression, microtitre plate assay, q-pcr is listed by: OMICtools
has parent organization: Bioconductor
Free, Available for download, Freely available OMICS_02312 SCR_003396 Delta-Delta-Ct 2026-02-07 02:06:02 319
ggbio
 
Resource Report
Resource Website
10+ mentions
ggbio (RRID:SCR_003313) software resource An R package for extending the grammar of graphics for genomic data. The graphics are designed to answer common scientific questions, in particular those often asked of high throughput genomics data. All core Bioconductor data structures are supported, where appropriate. The package supports detailed views of particular genomic regions, as well as genome-wide overviews. Supported overviews include ideograms and grand linear views. High-level plots include sequence fragment length, edge-linked interval to data view, mismatch pileup, and several splicing summaries. standalone software, unix/linux, mac os x, windows, r, infrastructure, visualization, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
PMID:22937822 Free, Available for download, Freely available biotools:ggbio, OMICS_04660 http://www.tengfei.name/ggbio/
https://bio.tools/ggbio
SCR_003313 ggbio - Visualization tools for genomic data 2026-02-07 02:06:16 13
NormFinder
 
Resource Report
Resource Website
1000+ mentions
NormFinder (RRID:SCR_003387) NormFinder software resource Software for identifying the optimal normalization gene among a set of candidates. It ranks the set of candidate normalization genes according to their expression stability in a given sample set and given experimental design. It can analyze expression data obtained through any quantitative method e.g. real time RT-PCR and microarray based expression analysis. NormFinder.xla adds the NormFinder functionality directly to Excel. A version for R is also available. normalization, gene is used by: RefFinder
is listed by: OMICtools
PMID:15289330 Free, Available for download, Freely available OMICS_02317 https://www.moma.dk/software/normfinder SCR_003387 NormFinder software - Determine the optimal normalization gene 2026-02-07 02:06:02 2382
PrimerSeq
 
Resource Report
Resource Website
1+ mentions
PrimerSeq (RRID:SCR_003295) PrimerSeq software resource Software that designs RT-PCR primers that evaluate alternative splicing events by incorporating RNA-Seq data. It is particularly advantageous for designing a large number of primers for validating alternative splicing events found in RNA-Seq data. It incorporates RNA-Seq data in the design process to weight exons by their read counts. Essentially, the RNA-Seq data allows primers to be placed using actually expressed transcripts. This could be for a particular cell line or experimental condition, rather than using annotations that incorporate transcripts that are not expressed for the data. Alternatively, you can design primers that are always on constitutive exons. PrimerSeq does not limit the use of gene annotations and can be used for a wide array of species. primer, rna-seq, rt-pcr, windows, mac os x, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
PMID:24747190 Free, Available for download, Freely available biotools:primerseq, OMICS_02328 https://bio.tools/primerseq SCR_003295 Primer Seek in RNA-Seq 2026-02-07 02:06:15 7
OmicCircos
 
Resource Report
Resource Website
50+ mentions
OmicCircos (RRID:SCR_003292) software resource An R software application and package used to generate high-quality circular plots for visualizing genomic variations, including mutation patterns, copy number variations (CNVs), expression patterns, and methylation patterns. standalone software, unix/linux, mac os x, windows, r, annotation, statistical method, visualization is listed by: OMICtools
has parent organization: Bioconductor
PMID:24526832 Free, Available for download, Freely available OMICS_04659 http://www.bioconductor.org/packages/release/bioc/html/OmicCircos.html SCR_003292 OmicCircos: High-quality circular visualization of omic data 2026-02-07 02:05:59 78
MIPgen
 
Resource Report
Resource Website
10+ mentions
MIPgen (RRID:SCR_003325) software resource Software for a fast, simple way to generate designs for MIP assays targeting hundreds or thousands of genomic loci in parallel. Packaged with MIPgen are scripts that aid in visualization of MIP designs and processing of MIP sequence reads to SAM files that can then be passed through any standard variant calling pipeline. standalone software, c++, python, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: University of Washington; Seattle; USA
PMID:24867941 Free, Available for download, Freely available OMICS_04657, biotools:mipgen https://github.com/shendurelab/MIPGEN
https://bio.tools/mipgen
SCR_003325 MIPgen - One stop MIP design and analysis 2026-02-07 02:06:00 47
PoPoolation2
 
Resource Report
Resource Website
100+ mentions
PoPoolation2 (RRID:SCR_003284) software resource Software to compare allele frequencies for SNPs between two or more populations and to identify significant differences. PoPoolation2 requires next generation sequencing data of pooled genomic DNA (Pool-Seq). It may be used for measuring differentiation between populations, for genome wide association studies and for experimental evolution., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. standalone software, next generation sequencing, population genetics, population genomics, statistics, toolkit, population is listed by: OMICtools
has parent organization: Google Code
PMID:22025480 Free, Available for download, Freely available OMICS_05824 SCR_003284 2026-02-07 02:06:15 242
DAFGA
 
Resource Report
Resource Website
1+ mentions
DAFGA (RRID:SCR_003319) software resource A python script package which estimates the evolutionary rate of a particular functional gene in a standardized manner by relating its sequence divergence to that of the 16S rRNA gene. It provides gene-specific parameter sets for OTU clustering and taxonomic assignment at desired rank, and it can be implemented into the diversity measurements offered by QIIME or Mothur. standalone software, python is listed by: OMICtools PMID:24939150 Free, Available for download, Freely available OMICS_04654 SCR_003319 DAFGA: Diversity Analysis of Functional Gene Amplicons, Diversity analysis of Functional Gene Amplicons 2026-02-07 02:06:16 1
Snakemake
 
Resource Report
Resource Website
100+ mentions
Snakemake (RRID:SCR_003475) Snakemake software resource A Python based language and execution environment for make-like workflows. The system supports the use of automatically inferred multiple named wildcards (or variables) in input and output filenames. python, workflow, bio.tools is used by: RiboSnake
is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Google Code
PMID:22908215
DOI:10.1093/bioinformatics/bts480
Free, Available for download, Freely available OMICS_02299, biotools:snakemake https://snakemake.github.io/ SCR_003475 snakemake - A Python based language and execution environment for make-like workflows 2026-02-07 02:06:20 353
PheWAS R Package
 
Resource Report
Resource Website
1+ mentions
PheWAS R Package (RRID:SCR_003512) software resource Software package contains methods for performing Phenome-Wide Association Study. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Vanderbilt University; Tennessee; USA
PMID:20335276 Free OMICS_00242, biotools:phewas https://bio.tools/phewas SCR_003512 Phenome-Wide Association Study 2026-02-07 02:06:21 6

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