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http://eagle-i.itmat.upenn.edu/i/0000013f-5317-8a44-a468-831a80000000

Core facility that provides the following services: Optical/bioluminescence in vivo imaging, Small animal bioluminescence/fluorescence imaging support services. The Optical/Bioluminescence Sub-Core of the SAIF provides the capability to perform cellular and molecular non-invasive in-vivo bioluminescence, fluorescence or near-infrared imaging. The instrumentation allows sensitive, non-invasive molecular imaging for a variety of applications including detection and quantification of various bioluminescent or fluorescent reporter-expressing cells or tissues (in culture or in small animals). The facility currently houses a Perkin Elmer IVIS Lumina II, two LI-COR Pearl Impulse Imagers and a Perkin Elmer IVIS Spectrum. The Facility offers assistance with experimental design, regulatory approval, troubleshooting, data management, analysis and display.

Proper citation: Penn Small Animal Imaging Facility: Optical/Bioluminescence Sub-Core (RRID:SCR_010033) Copy   

•   Source: SciCrunch Registry

http://www.med.upenn.edu/gtp/vectorcore/

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 30,2023. Core whose main aim is to provide vector technology for preclinical studies and other basic research applications. Its services include rovision of AAV, adenoviral and lentiviral based vectors, consultation and advice in the design of custom vectors and in vector serotype/pseudotype selection, and design, cloning and production of plasmid DNA for the production of custom vectors.

Proper citation: University of Pennsylvania Center for Molecular Therapy for Cystic Fibrosis Vector Core Facility (RRID:SCR_010038) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/00000142-345f-30d3-91c7-0c6080000000

The CTRC Sleep Core provides services in support of clinical sleep research. It is based at two sites: the CHOP Sleep Laboratory, convenient to the CTRC Outpatient Facility on the 7th Floor of Main Hospital and the University of Pennsylvania?s Sleep Laboratory, located on the 11th Floor of the Gates Building which is part of the medical complex of the Hospital of the University of Pennsylvania. The Sleep Core contains a total of six designated research beds, dedicated staff, and state-of-the-art equipment that provides support for a variety of sleep-related research initiatives. Studies performed in the Sleep Core include overnight polysomnography, multiple sleep latency testing, neurobehavioral testing and actigraphy. The Sleep Core��s goals include providing highest-quality sleep studies, extending sleep research to disciplines not traditionally involved in this area, further developing extant multidisciplinary programs, and offering training opportunities for medical students, residents, fellows, and junior faculty in clinical sleep research. The Sleep Core is associated with CHOP?s and UPHS? American Academy of Sleep Medicine-accredited Sleep Center Laboratories. Services for pediatric and adult subjects: * Study Design * Overnight Polysomnography ** Polysomnography Interpretation * Multiple Sleep Latency Testing * Actigraphy * Neurobehavioral testing * Sleep Core Library

Proper citation: Penn/CHOP CTRC Sleep Core (RRID:SCR_010041) Copy   

•   Source: SciCrunch Registry

http://upr.eagle-i.net/i/0000012b-00c0-7187-9e37-5ded80000000

Patient Coordinator Services is responsible for scheduling the subjects for the research-related appointments; her goal is to facilitate the participation of the subjects in the clinical studies in collaboration with the research staff and the investigators.

Proper citation: Puerto Rico Clinical and Translational Research Consortium Patients Coordinator Services (RRID:SCR_010045) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/00000138-7c65-0571-fbab-3b8480000000

Core facility that provides the following services: Microscope access service, Imaging experimental design consultation service, Confocal microscopy service, Microscopy training service, Scanning electron microscopy sample preparation service, Sputter coating access service, Scanning electron microscope access service. The Cell & Developmental Biology (CDB) Microscopy Core is a full-service facility serving the entire University of Pennsylvania community. Our aim is to provide personalized assistance on all aspects of imaging, from tips on sample preparation to training on one of our microscopes to processing and analysis of image data. Our facility currently houses five confocal and three widefield light microscopes, a scanning electron microscope, and several computers dedicated to image processing and analysis.

Proper citation: Penn Cell and Developmental Biology Microscopy Core (RRID:SCR_010004) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/00000138-9a9a-cba0-9cd7-d7e280000000

Core facility that provides the following services: NMR spectrometer access, NMR spectrometer training, NMR spectroscopy service, Consultation service for NMR experimental design. Penn Chemistry NMR Facility provides researchers in the Chemistry and Materials Science and Engineering department access to state-of-the-art instrumentation for high resolution NMR spectroscopy. The Facility provides users extensive training to use spectrometers without supervision and expert advice/consultation on advanced applications of NMR spectroscopy to solve research problems. At present, the Facility operates ten high resolution NMR spectrometers (300-600 MHz) of varying capabilities located in the Chemistry building at the corner of 34th and Spruce street, Philadelphia, PA. Penn Chemistry NMR Facility provides limited solution NMR services (data acquisition and spectrum/structure analysis) to other departments/centers of University of Pennsylvania based on hourly charges. However, these services will be limited to the availability of instrument time and personnel. NMR Facility accepts service samples from outside academic and industrial customers based on per hour charges.

Proper citation: Penn Chemistry NMR Facility (RRID:SCR_010005) Copy   

•   Source: SciCrunch Registry

http://hawaii.eagle-i.net/i/00000130-492c-c443-cec9-714480000000

The Clinical Protocol and Data Management Shared Resource (CPDM) is a component of the Center?s Clinical Trials Unit that provides central management and oversight of all clinical trials activities of the Center. The Shared Resource provides a range of management and quality control functions that are essential for conducting clinical trials research in Hawaii?s decentralized community practice setting. It includes a central location for all cancer protocols, a centralized database of protocol-specific data, an updated list of currently active protocols for the use of Center investigators, and status reports of protocols. It provides a centralized organization for activating and monitoring protocols throughout Hawaii?s multiple community offices and medical centers involving several Institutional Review Boards (IRBs). Quality control functions include: insuring subject safety and compliance with federal requirements through the Data and Safety Monitoring plan, insuring staff competency through training for research nurses, CRAs, clinical trials assistants and community office, clinic, and hospital staff engaged in Hawaii?s cancer clinical trials enterprise, and insuring recruitment of underserved minorities through focused outreach activities.

Proper citation: UH Manoa Clinical Protocol and Data Management Shared Resource (RRID:SCR_010094) Copy   

•   Source: SciCrunch Registry

http://hawaii.eagle-i.net/i/0000012b-3598-59d9-2f73-b43980000000

The Evolutionary Genetics Core Facility (EGCF) at the Hawaii Institute of Marine Biology (HIMB) is located on Coconut Island in Kaneohe Bay, Oahu. The NSF EPSCoR-supported Core Facility provides technical services and support for the faculty and students doing research at HIMB and the University of Hawaii system, as well as other institutions worldwide. The EGCF provides access to various instrumentation and equipment and offers fee-based genomic services including sequence and fragment analysis. The EGCF manager is available to provide services and assist with questions regarding lab instrumentation or protocols.

Proper citation: UH Manoa Evolutionary Genetics Core Facility (RRID:SCR_010095) Copy   

•   Source: SciCrunch Registry

http://hawaii.eagle-i.net/i/0000012b-3599-35df-2f73-b43980000000

HURL''s facilities include two deep-diving (2000 m) submersibles Pisces V and Pisces IV, a remotely operated vehicle RCV-150, and the support ship R/V Ka''imikai-o-Kanaloa. The two submersibles are housed and maintained at Makai Pier. HURL Data Archive: HURL provides a data package for each Pisces IV, Pisces V or RCV-150 dive. This package includes voice transcripts (Pisces IV & V only), graphs of environmental data (Pisces IV & V only), copies of videotapes with videologs, and copies of up to 250 slides with a photolog. The Data Archive is the custodian of the original data which remain the property of HURL. Databases of organisms and substrates observed on the dives are available for use by the principal investigator. Use of dive data by other scientists is subject to principal investigator approval for 2 years. HURL and NOAA-NURP reserve the right to use slides and video from dives for program promotion.

Proper citation: UH Manoa HURL Submersible Facility (RRID:SCR_010097) Copy   

•   Source: SciCrunch Registry

http://hawaii.eagle-i.net/i/0000012e-b6e0-c912-1247-b2dc80000000

HSFL was established in May 2007 within the School of Ocean and Earth Science and Technology (SOEST) and the College of Engineering (CoE) at the University of Hawaii. As a multidisciplinary research and education center HSFL brings together individuals from diverse areas to work on the exploration and understanding of the space environment. The mission of HSFL is to: * Promote innovative engineering and science research for terrestrial and planetary space missions. * Develop, launch, and operate small spacecraft from the Hawaiian Islands to accelerate the validation of new space technologies. * Provide workforce training in all aspects of unmanned space missions. * Build synergistic collaborations among educational, governmental, and corporate institutions interested in space exploration. Hawaii is located in a unique position to become a low-cost gateway to space and to place the University of Hawaii as the only university in the world to have both satellite fabrication capabilities and unique, direct access to orbital space. This will enable diverse missions that study Earth''s oceans and continents from low-Earth orbit, as well as the testing of engineering experiments in the hostile environment of space.

Proper citation: UH Manoa Hawaii Space Flight Laboratory (RRID:SCR_010098) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/00000138-7ce8-c10b-fbab-3b8480000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on June 1,2023. Core facility that provides the following services: Flow cytometry analysis service, Cell sorting and analysis service, Flow cytometer analyzer access, Introductory flow cytometry training, Advanced and customized flow cytometry training, Flow cytometry consultation service, FACSAria training, Flow cytometry data analysis, BSL2+ biohazardous human cell sorting, BSL2+ murine biohazardous cell sorting, BSL2+ murine cell sorting access, Non-infectious cell sorting access. The Flow Cytometry and Cell Sorting Resource Laboratory is currently recognized as one of the largest and most comprehensive flow cytometry laboratories in the US. In 2010 it was designated a laboratory of exceptional merit by the National Cancer Institute. Using state-of-the-art technology, the resource provides a broad array of, instrumentation, support, education and consultation to the research community at the University of Pennsylvania. A wide variety of cell sorting applications are supported, from high-speed multicolor (up to 14 colors) cell sorting to low-speed, large nozzle, improved viability sorting. Additionally, a wide variety of cell analysis services (up to 20 parameters) are offered, from traditional analog, easier to use tabletop analyzers to many-laser, many-color, high-speed, fully-digital modern instrumentation. Currently the facility offers 6 cell sorters and 19 analytical instruments. A very active training and consultation program is in place to support these activities. The Scientific Director, Dr. Jonni Moore, and the Technical Director, each have over 25 years experience in the field of cytomics. Researchers at the University of Pennsylvania are increasingly engaged in research projects that require 8-plus-parameter cell sorting of infectious cells and primary human tissues. Investigators using the Flow Cytometry and Cell Sorting Shared Resource have access to virtually any type of cytometric services required for a vast array of applications.

Proper citation: Penn Flow Cytometry and Cell Sorting Resource Laboratory (RRID:SCR_010011) Copy   

•   Source: SciCrunch Registry

http://hawaii.eagle-i.net/sweet/provider?uri=http://hawaii.eagle-i.net/i/0000012a-2513-2fac-c99c-aef680000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 30,2023. Core to provide bioinformatics analysis and consulting service, to increase the research capacity in bioinformatics in the State of Hawaii, to provides software applications, hardware, access, and support to researchers who utilize genomic and proteomic data. Undertake collaborative project with INBRE researchers to develop novel tools or applications that address specific needs. Develop an academic program in bioinformatics with the John A. Burns School of Medicine (JABSOM). Recruit a full-time junior faculty member to lead the academic program. Conduct training workshops and courses, and run a user support help desk.

Proper citation: University of Hawaii at Manoa INBRE Bioinformatics Core Facility (RRID:SCR_010099) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/00000138-9b39-142c-9cd7-d7e280000000

Core facility that provides the following services: Investigational drug services, Clinical trial support services. The IDS is charged with safe and responsible handling of investigational drugs. The purpose of the IDS is to maintain control and accountability of investigational drug use in the Medical Center to promote maximum benefit and safety for patients enrolled in studies. Investigational drugs are procured, stored, inventoried, dispensed and used through the IDS in compliance with regulations or guidelines of the FDA, JCAHO, ASHP, Code of Federal Regulations, Pennsylvania State Board of Pharmacy, other applicable organizations and in accordance with Hospital, Medical Center and University policies and guidelines.

Proper citation: Penn Investigational Drug Service (RRID:SCR_010012) Copy   

•   Source: SciCrunch Registry

http://hawaii.eagle-i.net/i/0000012b-1c5f-dcdf-06c2-9c7f80000000

Core facility that provides the following services: Real-time/quantitative PCR service, Long read (900bp) sequencing service, Microarray sample labeling service, Automated liquid handling service, DNA/RNA sample concentration service, Spectrophotometry service, Microarray scanning service. Offers services in the areas of qPCR, Microarray, Sequencing, and Other Genomic Services. May expand or remove services depending on need or interest. If you have recurring processes that you would like to automate or have us take over, we would be glad to sit down and talk with you to discuss how we can help you acheive your goals. We are aiming to be a self-sustaining entity consisting solely on a chargeback system. Our prices reflect the costs of equipment service contracts, potential and actual maintenence costs, as well as direct and indirect labor costs and administration. Our costs are kept low by being able to provide services in bulk with high throughput, it is therefore sometimes necessary to have minimum orders or fees in order to maintain a positive cost structure.

Proper citation: UH Manoa COBRE Genomics Core (RRID:SCR_010090) Copy   

•   Source: SciCrunch Registry

http://hawaii.eagle-i.net/i/0000012a-2512-b15c-c99c-aef680000000

Core facility that provides the following services: Fluorescent microscopy consultation service.

Proper citation: UH Manoa RCMI Molecular Pathology Core (RRID:SCR_010091) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/00000138-ba32-e90b-9cd7-d7e280000000

Core facility that provides the following services: Illumina sequencing service, 5500xl sequencing service. The recent boon in high-throughput sequencing technologies has offered enormous potential to applications in genome sequencing, transcriptome profiling, epigenetics, metagenomics, discovery of non-coding RNAs and protein binding sites. A primary mission of PGFI is to lead the development of new genomics technologies at the University of Pennsylvania. In response to the ever growing demand for high-throughput sequencing at Penn, PGFI?s HTS facility was established. In this facility, investigators have access to different types of HTS technology: Illumina?s HiSeq and Applied Biosystem?s SOLiD4 and 5500xl. With two HiSeqs, the facility can provide the latest innovation from Illumina featuring up to 3 billion paired-end reads (up to 100x100 bp reads) per flow cell, 8 lanes per flow cell and 2 flow cells per machine. With the SOLiD4, the facility can provide up to 1.4 billion reads per slide, 50 x 25 bp paired-end reads, up to 8 sectors per slide and 2 flow cells per machine. With the 5500xl, the facility can provide up to 180 Gb or more than 2.8 B reads per run. The 5500xl offers 75 bp fragment runs, 75x35 bp paired-end runs and up to 60 bp x 60 bp mate paired runs with the added bonus of pay-as-you-go sequencing. All platforms offer multiplexing capability. Currently Illumina offers 48 barcodes and Life Technologies offers 96 barcodes. The SOLiD 4 system provides greater than 99.94% accuracy due to 2-base encoding. The 5500xl offers up to 99.99% accuracy utilizing 2-base encoding and Exact Call Chemistry.

Proper citation: Penn High-Throughput Sequencing Facility (RRID:SCR_010015) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/00000138-e7cd-3f54-eb5b-b63c80000000

Core facility that provides the following services: Immunohistochemistry (IHC) staining service, Tissue processing and sectioning service, Staining service. The Histology and Gene Expression Core Facility provides expert professional services for members of the Cardiovascular Institute. Services for non- Institute investigators are available on a fee-for-service basis as time permits. The Histology and Gene Expression Core offers all histology-related services include tissue processing, embedding, sectioning, staining, immunocytochemistry and InSitu Hybridization.

Proper citation: Penn Histology and Gene Expression Core (RRID:SCR_010017) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/00000138-ba97-298d-9cd7-d7e280000000

Core facility that provides the following services: ELISA AND ELISpot assays, Multi-color flow cytometry immunophenotyping and proliferation assays, Luminex multiplex and Cytometric Bead immunological assays, Peripheral blood mononuclear cell isolation, Intraepithelial lymphocyte isolation from intestinal biopsy, Cryopreservation, Immunological assay training. The Human Immunology Core will provide expertise and instrumentation for the analysis of immune function in patients during treatment with anticancer drugs and immunotherapy. The Core will serve as a central facility for incorporating the newest technologies and performing validated immunology assays for phase I/II clinical studies, while also offering expert scientific and technical consultations to users interested in conducting this kind of innovative research.

Proper citation: Penn Human Immunology Core (RRID:SCR_010018) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/00000139-5064-ad11-4778-6c3080000000

Core facility that provides the following services: Mass spectrometer access. The Mass Spectrometry Facility is part of the Shared Instrument Facilities of the Department of Chemistry. It provides low and high resolution mass spectra to Penn Chemistry and to other research groups throughout the university community for the determination of elemental composition and purity of a wide variety of compounds. Investigators interested in using the facility are encouraged to call and discuss their project. Usage fees will be quoted at this time. Fees depend upon the instrument involved in the analysis, complexity of the project, training, etc.

Proper citation: Penn Mass Spectrometry Facility (RRID:SCR_010021) Copy   

•   Source: SciCrunch Registry

https://www.bioinformatics.upenn.edu/

Core facility that provides the following services: Desktop sequence analysis tools subscription, Database and web applications support, Genomic-scale sequencing analysis, Sequence analysis application support, Transcript profiling consultation service, Transcript profiling application support, Transcript profiling data analysis, Automating large or repetitive tasks, Web space for biological databases, Bioinformatics/genomics resource identification, and Data storage. The bioinformatics staff of the Penn Molecular Profiling Facility is available to provide experimental design and analytical services to users of the Facility and the basic and biomedical research community. Additional services are provided, including grant support, data management and custom computational projects. This facility provides one-on-one training and hosts instructional workshops. Their goal is to ensure that scientists across the University are able to exploit existing and emerging computational technologies, especially related to their genomics scale datasets.

Proper citation: University of Pennsylvania Molecular Profiling Facility Bioinformatics (RRID:SCR_010022) Copy   

•   Source: SciCrunch Registry