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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
Provides evolutionary and computational biology investigators with computing and large data storage capacity for use in analyzing and managing large volumes of research data. Core contains advanced mix of high performance computing clusters, servers and data storage components, knowledge and technical skills required to compress years of analysis into days.
Proper citation: Idaho University IBEST Computational Resources Core Facility (RRID:SCR_017734) Copy
https://weillcornellmicroscopy.org/overview
Core sassist users with all their microscopic imaging needs, from the conception of idea, to final image analysis and presentation. Offers regular widefield microscopes for fluorescence and brightfield imaging, laser scanning microscopes (confocal and multiphoton), super-high resolution microscope (Zeiss Airyscan), automated high content optical microscopy, and electron microscopy.Provides access to several image analysis software packages, and image analysis workstations that are optimized for handling large amounts of imaging data. Available software include MetaMorph, MetaXpress and Imaris, Fiji/ImageJ.
Proper citation: Weill Cornell Medical College Microscopy and Image Analysis Core Facility (RRID:SCR_017693) Copy
https://cell-innovation.nig.ac.jp/maser/Tools/visualization_top_en.html
One stop platform for NGS big data from analysis to visualization. There are about 400 analysis pipelines integrated on Maser. List of all analysis pipelines, including descriptions and approximate execution times, can be found on page for ‘All pipelines’ in the User Guide.. Regist custom genome software registers custom genomes to Genome Explorer (IN: FASTA).
Proper citation: regist custom genome (RRID:SCR_015999) Copy
Core for full DNA and RNA analysis services. Canada's largest integrated provider of sequencing, genotyping and biochips services. Offers scientific community around the world genomic services in support of research in human health, agrifood, forestry and sustainable development.
Proper citation: CES Genome Quebec Core Facility (RRID:SCR_017703) Copy
http://www.biotech.wisc.edu/facilities/dnaseq/home
Core provides sequencing resources. Service support for Illumina Next Generation and Sanger sequencing projects, from project design and sample preparation through downstream analysis. Provides DNA extraction, SNP genotyping, and fragment analysis services, and can facilitate custom projects upon request.
Proper citation: Wisconsin-Madison University Biotechnology Center DNA Sequencing Core Facility (RRID:SCR_017759) Copy
https://www.unr.edu/proteomics
Core offers mass spectral proteomic analysis. Assists with qualitative and quantitative characterization of proteins in biological matrices such as plasma/serum, tissue, cell lines and other biological material to gain understanding of physiological pathways, molecular interactions and regulatory signaling.
Proper citation: University of Nevada at Reno Nevada Proteomics Center Core Facility (RRID:SCR_017761) Copy
https://voices.uchicago.edu/ucflow/
Core offers services in cytometry and antibody technology, helps to design projects, data acquisition, analysis and/or interpretation beyond routine practices,critical drafting and/or revision of manuscript for intellectual content purposes.
Proper citation: Chicago University Cytometry and Antibody Technology Core Facility (RRID:SCR_017760) Copy
Services include advise on microscope to use for research project, image acquisition, optimization image analysis and sample preparation, free of charge access to 500GB per laboratory on CMCI server in order to store data for project. Facility houses four wide-field, near-field (TIRF), three confocal (swept-field and laser-scanning) microscopes and laser capture microdissection system.
Proper citation: Concordia University Center for Microscopy and Cellular Imaging Core Facility (RRID:SCR_017804) Copy
Provides services in sequencing using ABI model 3730 DNA Sequencer with the XL Upgrade,design and have synthesized primers for primer walking experiments, DNA fragment analysis such as microsatellites, AFLP, SNP analysis.
Proper citation: Maine University DNA Sequencing Core Facility (RRID:SCR_017803) Copy
http://chemistry.vcu.edu/research/facilities/chemical-and-proteomic-mass-spectrometry-core-facility/
Core provides mass spectrometric services, from basic mass measurement to complex proteome analyses.Services include basic mass measurement, ESI-MS/MS,LC-MS,Exact mass measurement,Protein identification.
Proper citation: Virginia Commonwealth University Chemical and Proteomic Mass Spectrometry Core Facility (RRID:SCR_017806) Copy
http://nmr.uthscsa.edu/contact.shtml
Core offers high field NMR instrumentation for structural studies of biological macromolecules. Instrumentation includes four-channel Bruker Avance 500, 600, and 700 MHz NMR spectrometers, ultra high sensitivity 5mm 1H-13C-15N triple-resonance cold probe for 600 MHz spectrometers. Service include acquisition and analysis of required spectra for elucidation of small molecule structures (includes synthetic molecules, natural products, cofactors, lipids, and short peptides (30 amino acids or less)). Types of projects conducted collaboratively include determination of three-dimensional structures of biological macromolecules, including proteins and nucleic acids, both alone and as complexes with various ligands.
Proper citation: Texas University Health Science Center at San Antonio Biomolecular NMR Core Facility (RRID:SCR_017775) Copy
Core research facility providing genomic services that include next generation sequencing , single cell sequencing, metagenomic, targeted amplicon sequencing, and Sanger sequencing.
Proper citation: University of Missouri-Columbia DNA Core Facility (RRID:SCR_017778) Copy
http://biochem.slu.edu/proteincore/coreindex.shtml
Core facility that supports expression, purification, and analysis of reagent and preclinical proteins by providing instrumentation and consultation for protein production from small to large scale. Available equipment includes shaking incubators, 5 L fermentor, high pressure cell disruptor, hollow fiber concentrator, Maxwell16 magnetic bead purification system, AKTA Purifier chromatograph, analytical ultracentrifuge, analytical HPLC, and MALDI-QIT-TOF mass spectrometer.
Proper citation: Saint Louis University School of Medicine Protein Core Facility (RRID:SCR_017811) Copy
Research oriented service laboratory providing informatics support to research community. Services include data analysis and mining in proteomics, genomics and chemistry, systems biology approaches such as pathway, network and interaction analyses, large scale statistical and machine learning studies, protein structure, function and stability prediction, sequence and domain analyses,d esign and implementation of relational databases and software programs, consultation on experimental design involving data acquisition, management and analysis, report, grant, and manuscript preparation.
Proper citation: Kansas University at Lawrence Applied Bioinformatics Laboratory Core Facility (RRID:SCR_017751) Copy
https://www.unmc.edu/vcr/cores/vcr-cores/mgec/index.html
Core Facility provides expertise and advice for experimental design of transgenic or gene knockout experiments, including DNA construct production and genotyping assays, makes reagents available for generation of transgene or gene targeting constructs, and performs all experimental aspects, which include pronuclear injection of transgene constructs, generation of recombinant mouse ES cells, blastocyst injection, and embryo transfer surgeries, for generation or rederivation of genetically manipulated mouse strains. Transgenic founder mice or chimeric animals with targeted alleles are then transferred to individual investigator for analysis.
Proper citation: Nebraska University Medical Center Mouse Genome Engineering Core Facility (RRID:SCR_017755) Copy
http://www.med.unc.edu/csb/unc-peptides
Core offers services for: High quality synthetic peptides, stable isotope labeled peptides, peptides with PTM and fluorescent and affinity tags, synthesis of peptide libraries. Analysis of synthetic peptides. Purification, lyophilization and aliquoting of synthetic peptides.
Proper citation: North Carolina University at Chapel Hill School of Medicine High Throughput Peptide Synthesis and Array Core Facility (RRID:SCR_017837) Copy
http://bioimaging.dbi.udel.edu
Microscopy facility that houses equipment including confocal microscopes: LSM780 confocal microscope (Located at CBBI),LSM880 confocal microscope (Located at DBI 117),electron microscopes and their accessory instrumentation:Thermo Scientific Apreo VS SEM microscope,Hitachi S-4700, Leica EM ACE600 and Tousimis Autosamdri-815B,CX7 high content analysis system. Our staff has technical expertise across different microscopy platforms and methodologies.
Proper citation: University of Delaware BioImaging Center Core Facility (RRID:SCR_017814) Copy
Provides system for Splicing isoform Annotation. This LISA platform allows high throughput annotation and functional analysis of Alternate Splicing in humans.
Proper citation: Quebeck Sherbrooke University Genomic Core Facility (RRID:SCR_017785) Copy
http://hihg.med.miami.edu/cgt/genotyping
Core provides services in analyzing genetic variation, performing genome-wide association studies, conducting non-human genotyping. Offers flexible platforms from low to high throughput, tailored to research needs. Specializes in Illumina Genotyping Arrays and TaqMan Allelic Discrimination Assays, with fully automated processing using Tecan EVOs and BioMek liquid handlers and Genologics LIMS for reliable data tracking.Applications include: GWAS – Identify genetic variants linked to traits and diseases; PRS Analysis – Assess genetic risk for complex diseases; Pharmacogenomics – Study genetic factors in drug response; Population Genetics – Explore ancestry and genetic diversity; CNV Analysis – Detect large-scale genomic variations; Methylation Analysis.
Proper citation: University of Miami Hussman Institute for Human Genomics Genotyping Core Facility (RRID:SCR_017820) Copy
http://proteomics.rockefeller.edu/
Core provides analysis of proteins, peptides, lipids, polar metabolites and small molecules by high resolution/high mass spectrometry. Targeted and hypothesis free analysis are offered combined with relative quantitation based on either label free, tandem mass tags or metabolic labelling. Acquisition tools include Data Dependent (DDA) and Data Independent (DIA).
Proper citation: The Rockefeller University Proteomics Resource Center Core Facility (RRID:SCR_017797) Copy
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