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http://ftp://ftp.biomath.jussieu.fr/pub/mlbgh (not available)
Software application that is an extension of the GENEHUNTER program to perform sib-pair and sib-ship linkage analysis using the Maximum Likelihood Binomial (MLB) method. (entry from Genetic Analysis Software)
Proper citation: MLBGH (RRID:SCR_009297) Copy
http://mga.bionet.nsc.ru/soft/mitpene/mitpene.html (in Russian)
Software program for analysis of mitochondrial diseases (entry from Genetic Analysis Software)
Proper citation: MITPENE (RRID:SCR_009294) Copy
http://www.uni-kiel.de/medinfo/mitarbeiter/krawczak/download/index.html
Software application (entry from Genetic Analysis Software)
Proper citation: MKGST (RRID:SCR_009295) Copy
http://genome.sph.umich.edu/wiki/Minimac
Software application that is a low memory, computationally efficient implementation of the MaCH algorithm for genotype imputation. It is designed to work on phased genotypes and can handle very large reference panels with hundreds or thousands of haplotypes. The name has two parts. The first, mini, refers to the modest amount of computational resources it requires. The second, mac, is short hand for MaCH, our widely used algorithm for genotype imputation. (entry from Genetic Analysis Software)
Proper citation: MINIMAC (RRID:SCR_009292) Copy
http://www.mds.qmw.ac.uk/statgen/dcurtis/software.html
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 16,2023. Software application (entry from Genetic Analysis Software)
Proper citation: MFLINK (RRID:SCR_009290) Copy
http://www.uni-hohenheim.de/~frisch/software.html
Software application (entry from Genetic Analysis Software)
Proper citation: PLABSIM (RRID:SCR_009328) Copy
http://www.people.fas.harvard.edu/~junliu/plem/
Software application (entry from Genetic Analysis Software)
Proper citation: PL-EM (RRID:SCR_009329) Copy
http://www.sanger.ac.uk/resources/software/peer/
Software collection of Bayesian approaches to infer hidden determinants and their effects from gene expression profiles using factor analysis methods. Applications of PEER have * detected batch effects and experimental confounders * increased the number of expression QTL findings by threefold * allowed inference of intermediate cellular traits, such as transcription factor or pathway activations This project offers an efficient and versatile C++ implementation of the underlying algorithms with user-friendly interfaces to R and python.
Proper citation: PEER (RRID:SCR_009326) Copy
http://www.sfbr.org/sfbr/public/software/pedsys/pedsys.html
Full-scale database system developed as a specialized tool for management of genetic, pedigree and demographic data. (entry from Genetic Analysis Software)
Proper citation: PEDSYS (RRID:SCR_009324) Copy
A Java Api for the visual analysis of large and complex pedigrees that provides all the necessary functionality for the interactive exploration of extended genealogies. Available packages are mostly focused on a static representation or cannot be added to an existing application; the goal of this open-source library is to provide an application program interface that enables the efficient construction of visual analytic applications for the analysis of family based data. (entry from Genetic Analysis Software)
Proper citation: PEDVIZAPI (RRID:SCR_009325) Copy
http://www.sph.umich.edu/csg/abecasis/Merlin
Software application that carries out single-point and multipoint analyses of pedigree data, including IBD and kinship calculations, nonparametric and variance component linkage analyses, error detection and information content mapping. For multipoint analyses in dense maps, Merlin allows the user to impose constraints on the number of recombinants between consecutive markers. Merlin estimates haplotypes by finding the most likely path of gene flow or by sampling paths of gene flow at all markers jointly. It can also list all possible nonrecombinant haplotypes within short regions. Finally, Merlin provides swap-file support for handling very large numbers of markers as well as gene-dropping simulations for estimating empirical significance levels. (entry from Genetic Analysis Software)
Proper citation: MERLIN (RRID:SCR_009289) Copy
http://www.medgen.de/index.html
Powerful pedigree drawing program with two drawing modes: Input mode for fast and automatic drawing; edit mode for text annotations, legends, special symbols. Both input and edit mode provide auto numbering, auto resizing of symbols and fonts, and zooming. PED 4.2a complies with the Recommendations for standardized human pedigree nomenclature. Apart from fully sizeable printed output, pedigrees can be exported as metafiles to virtually any Windows word processor or drawing program. (entry from Genetic Analysis Software)
Proper citation: PED (RRID:SCR_009320) Copy
http://www.genetics.ucla.edu/software/
Software application for genetic analysis of human pedigree data under models involving a small number of loci. MENDEL is useful for segregation analysis, linkage calculations, genetic counseling, allele frequency estimation, and related kinds of problems. (entry from Genetic Analysis Software)
Proper citation: MENDEL (RRID:SCR_009288) Copy
Software program for detecting autosomal marker Mendelian incompatibilities in pedigree data (entry from Genetic Analysis Software)
Proper citation: PEDAGREE (RRID:SCR_009321) Copy
http://watson.hgen.pitt.edu/register/
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 16,2023. Software application that uses as input a trio of files: 1) a LINKAGE-format locus file modified to contain locus name information; 2) a LINKAGE-format pedigree file; and 3) a map file. Mega2 then takes this trio of input files and, via a menu-driven interface, transforms them into various other file formats, thus greatly facilitating a variety of different analyses. In addition, for many of these options, it also sets up a C-shell script that then can automatically run these analyses (if you are using Mega2 in a Unix environment that supports C-shell scripts). (entry from Genetic Analysis Software)
Proper citation: MEGA2 (RRID:SCR_009286) Copy
Software application for mapping of quantitative trait loci (QTLs) for several types of mapping populations: BC1, F2, RILs, (doubled) haploids, full-sib family of outbreeders. Analyses: interval mapping, composite interval mapping, nonparametric mapping, automatic cofactor selection, permutation test for interval mapping. QTL charts. Everything available in an intuitive MS-Windows user interface. (entry from Genetic Analysis Software)
Proper citation: MAPQTL (RRID:SCR_009284) Copy
http://www.broad.mit.edu/ftp/distribution/software/mapmaker3/
Software application (entry from Genetic Analysis Software)
Proper citation: MAPMAKER/EXP (RRID:SCR_009281) Copy
https://github.com/gaow/genetic-analysis-software/blob/master/pages/MAPMAKER%26HOMOZ.md
Software application that calculates multipoint lod scores in pedigrees with inbreeding loops (entry from Genetic Analysis Software)
Proper citation: MAPMAKER/HOMOZ (RRID:SCR_009282) Copy
http://ftp://linkage.rockefeller.edu/software/relative
Software application for relationship estimation, in particular between putative sibs when parents are untyped (entry from Genetic Analysis Software)
Proper citation: RELATIVE (RRID:SCR_009355) Copy
http://genome.sph.umich.edu/wiki/RelativeFinder
Software program for checking relationships between pairs of individuals. There are many excellent programs that carry out similar tasks. Some of the unique features in relativeFinder are the batch mode options, that allow large jobs to be divided into many smaller jobs (suitable for deployment on a compute cluster environment), and the flexibility of the underlying Merlin engine, which allows relative finder to handle large pedigrees and consider a variety of alternate relationships -- including potential relationships specified by the user on the fly. (entry from Genetic Analysis Software)
Proper citation: RELATIVEFINDER (RRID:SCR_009356) Copy
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