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https://www.derc.cuimc.columbia.edu/services/advanced-tissue-pathology-and-imaging-core

Core that provides spectrum of advanced cellular and tissue pathology and imaging services for diabetes researchers at Columbia University. It also has microscopy equipment and services such as confocal, live 2-photon and scanning and transmission electron microscopy.

Proper citation: Columbia Diabetes Research Center Advanced Tissue Pathology and Imaging Core Facility (RRID:SCR_015085) Copy   

•   Source: SciCrunch Registry

http://www.hopkinsmedicine.org/diabetes-research-center/research-cores/cell-biology.html

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 9,2024. Core that provides services in tissue analysis and imaging, islet biology, liver biology, and adipocyte biology. It includes the indepedent cores Derivation of IPSC and Bioenergetics as well as the Specialty Animal Surgery Subcore and Bone Biology Subcore.

Proper citation: Johns Hopkins University - University of Maryland Diabetes Research Center Cell Biology Core (RRID:SCR_015090) Copy   

•   Source: SciCrunch Registry

http://drtc.bsd.uchicago.edu/islet-cell-biology-core-about/

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on November 7,2024. Core which provides services and hands-on training in the isolation and functional characterization of pancreatic islets from normal and diabetic humans and mice. It also maintains a repository of insulinoma cell lines for distribution. It puts emphasis on facilitating studies of primary islet cells and it has developed many unique tools and techniques for carrying such studies including novel animals models, biophysical methods and a library of adenovirus-based expression constructs for studying beta-cell function.

Proper citation: University of Chicago Diabetes Research and Training Center Islet Cell Biology Core (RRID:SCR_015132) Copy   

•   Source: SciCrunch Registry

http://www.hopkinsmedicine.org/diabetes-research-center/research-cores/healthcare-population.html

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 9,2024. Contains description of and contact information for multiple health and social science departments.

Proper citation: Johns Hopkins University - University of Maryland Diabetes Research Center Health and Populations Science Core (RRID:SCR_015093) Copy   

•   Source: SciCrunch Registry

https://diabetescenters.org/cores/ucsd-ucla-genomics-and-epigenetics-core

Core which provides Diabetes Research Center investigators access to high-throughput sequencing, data acquisition and analysis. Its main services include Sample QC and Processing, Illumina Platform Library Preparation and Sequencing, and Expression microarrays (RNA, microRNA).

Proper citation: University of California San Diego - University of California Los Angeles Diabetes Research Center Genomics and Epigenetics Core Facility (RRID:SCR_015097) Copy   

•   Source: SciCrunch Registry

http://depts.washington.edu/diabetes/viral-vector-and-transgenic-mouse/

Core facility that provides Diabetes Research Center affiliates with vectors necessary to overexpress, knockdown, knockout, or alter expression of RNAs and proteins of interest in cultured cells, isolated tissues, and animals.

Proper citation: University of Washington Diabetes Research Center Vector and Transgenic Mouse Core (RRID:SCR_015130) Copy   

•   Source: SciCrunch Registry

https://www.iths.org/resources/directory/listing/drc-quantitative-and-functional-proteomics-core-university-of-washington

Core facility that provides the powerful tools of modern mass spectrometry and complex data set analysis to Diabetes Research Center investigators to permit structural identification and quantitation of proteins involved in diabetes and its complications.

Proper citation: University of Washington Diabetes Research Center Quantitative and Functional Proteomics Core Facility (RRID:SCR_015131) Copy   

•   Source: SciCrunch Registry

https://diabetescenters.org/cores/ucsd-ucla-metabolic-and-molecular-physiology-core

Provides DRC investigators with thorough scientific consultation and timely, accurate, and easily accessible mouse, tissue, and cellular phenotyping. Services include whole animal, tissue and cellular metabolism, insulin action, and inflammatory signaling as well as cardiac, vascular and renal phenotyping associated with diabetes complications research. It also administers drugs and other substances to mice by different routes in a well-controlled setting.

Proper citation: University of California San Diego - University of California Los Angeles Diabetes Research Center Metabolic and Molecular Physiology Core Facility (RRID:SCR_015095) Copy   

•   Source: SciCrunch Registry

http://digestivediseasescenters.org/content/ddrc-texas-medical-center-cellular-molecular-morphology-core

Core facility whose services include histology, immunohistochemistry, RNA in situ hybridization, mRNA probe generation, frozen sections for enzyme histochemistry, immunofluorescent antibody studies, live and fixed cell confocal, deconvolution microscopy and super resolution microscopy (SIM and STORM), and transmission electron microscopy, quantitative morphometric analysis, high throughput microscopy and high content analysis, laser capture microdissection for molecular genetic analyses, and digital images for internet communication and publication.

Proper citation: Texas Medical Center Digestive Diseases Center Cellular and Molecular Morphology Core (RRID:SCR_015219) Copy   

•   Source: SciCrunch Registry

https://www.bcm.edu/research/centers/digestive-disease/core-facilities/study-design-and-clinical-research

Core that provides epidemiological and biostatistical support for design and analysis, and also provides investigators with access to the clinical specimens required for their basic and translational research activities. It offers assistance as well as didactic training in issues involving local and foreign IRB?s, HIPPA regulations, and importing or exporting clinical specimens.

Proper citation: Texas Medical Center Digestive Diseases Center Study Design and Clinical Research Core Services (RRID:SCR_015218) Copy   

•   Source: SciCrunch Registry

https://www.bcm.edu/research/centers/digestive-disease/core-facilities/integrative-biology

Core that aims to provide turnkey access to organoids/enteroid technologies to TMC-DDC researchers. These include samples (enteroids, organoids), reagents (specialized growth media, etc.), training, and consultative expertise. The core also provides access to gnotobiotic facilities and animals, training and consultative expertise.

Proper citation: Texas Medical Center Digestive Diseases Center Integrative Biology Core (RRID:SCR_015220) Copy   

•   Source: SciCrunch Registry

http://www.massgeneral.org/csibd/cores/clinical.aspx

Core whose objective is to provide an infrastructure that facilitates the translation of basic research findings into the clinic. Its services include consultation, training, and education, biospecimen services, and facilitating data collection and analysis.

Proper citation: Center for the Study of Inflammatory Bowel Disease Clinical Core (RRID:SCR_015227) Copy   

•   Source: SciCrunch Registry

https://cdtr.wustl.edu/our-cores/research-partnerships-with-american-indianalaska-native-core/

Core facility whose services include consultation for community engagement strategies, communication with Native and non-Native American policy experts, and technical assitance in developing culturally appropriate study paradigms.

Proper citation: Washington University Center for Diabetes Translation Research Research Partnerships with American Indian/Alaskan Native Communities Core (RRID:SCR_015183) Copy   

•   Source: SciCrunch Registry

http://www.massgeneral.org/csibd/cores/morphology.aspx

Core that provides CSIBD investigators with the technical support, expertise and access to instrumentation necessary for their morphological and cell biological studies related to IBD. These services include routine tissue fixation and processing for light microscopy, imaging flow cytometry, perfusion-fixation of organs, conventional electron microscopy, low temperature embedding in Lowicryl HM20, and immunocytochemistry.

Proper citation: Center for the Study of Inflammatory Bowel Disease Morphology Core (RRID:SCR_015228) Copy   

•   Source: SciCrunch Registry

http://www.mayo.edu/research/centers-programs/center-cell-signaling-gastroenterology-c-sig/cores-services/clinical-core

Core facility which supports faculty research by facilitating access to human biospecimens. Its services include centralized access to participating Mayo Clinic GI biobanks and other institutional biospecimen resources, de-identified, phenotypic and demographic data, and coordination of fresh tissue acquisition from surgical pathology.

Proper citation: Mayo Clinic Center for Cell Signaling in Gastroenterology Clinical Core (RRID:SCR_015229) Copy   

•   Source: SciCrunch Registry

https://keck.usc.edu/liver-diseases-research-center/about-the-center/scientific-cores/

Core facility which provides primary hepatocytes cultures of normal and diseased mice and rats and various cell lines to investigators. The cell separation subcore plays a role in translational research in DILI and alcoholic hepatitis, supporting funded studies of the role of innate and adaptive immune systems in elucidating pathophysiology, identifying biomarkers, and predicting response to treatments.

Proper citation: USC Liver Transplant Program and Center for Liver Disease Cell Separation and Culture Core (RRID:SCR_015233) Copy   

•   Source: SciCrunch Registry

http://cure.med.ucla.edu/cores/administrative

Management core that develops mission, goals, and strategies relating to the functioning of the CURE:DDRCC.

Proper citation: CURE - Digestive Diseases Research Center Administrative Core (RRID:SCR_015231) Copy   

•   Source: SciCrunch Registry

https://www.cincinnatichildrens.org/research/divisions/d/dhc/cores/pluripotent-stem-cell

Core whose services include generation of human induced pluripotent stem cells (iPSCs) from DHC-relevant patient cells and directed differentiation of human pluripotent stem cells (hPSCs) to human intestinal organoids (HIOs).

Proper citation: Cincinnati Digestive Health Center Pluripotent Stem Cell and Organoid Core (RRID:SCR_015199) Copy   

•   Source: SciCrunch Registry

https://keck.usc.edu/liver-diseases-research-center/about-the-center/scientific-cores/

Core that maintains and provides access and training in the use of a large base of major and expensive equipment, including thermocyclers, plate readers, centrifuges, a wide range of customized HPLC services, and Seahorse metabolic applications.

Proper citation: USC Liver Transplant Program and Center for Liver Disease Analytical Metabolic Instrumentation Core (RRID:SCR_015232) Copy   

•   Source: SciCrunch Registry

http://www.massgeneral.org/csibd/cores/genetic.aspx

Core whose services include breeding and maintenance of mutant mouse stocks, characterization of murine models, bone marrow transfers and adoptive T cell transfers, in vivo tracking of fluorescently labeled bacteria and cells, and whole body imaging of bioluminescent and fluorescent signals.

Proper citation: Center for the Study of Inflammatory Bowel Disease Genetic Animal Models Core (RRID:SCR_015238) Copy   

•   Source: SciCrunch Registry