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Cellosaurus is database indexing available cell lines from various collections: American Type Culture Collection (ATCC), Bioresource Collection and Research Center, Taiwan (BCRC), Banco de Células do Rio de Janeiro (BCRJ), CellBank Australia (CBA), Collection of Cell Lines in Veterinary Medicine (CCLV), Cell Lines Service (CLS), Coriell, Drosophila Genomics Resource Center (DGRC), Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (DSMZ), European Bank for induced pluripotent Stem Cells (EBiSC), European Collection of Authenticated Cell Cultures (ECACC), Interlab Cell Line Collection (ICLC), Institute for Fermentation Osaka (IFO), Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna (IZSLER) biobank, Japanese Collection of Research Bioresources (JCRB) Cell Bank, Kunming Cell Bank of Type Culture Collection (KCB), Korean Cell Line Bank (KCLB), Millipore, National Cell Bank of Iran (NCBI_Iran), National Cancer Institute - Developmental Therapeutics Program (NCI-DTP), NINDS Human Cell and Data Repository (NHCDR), NIH AIDS Reagent Program (NIH-ARP), NISES, RIKEN Bioresource Center Cell Bank (RCB), Royan Stem Cell Bank (RSCB), Tick Cell Biobank (TCB), Tohoku University cell line catalog (TKG), and Ximbio.
Discontinued
https://web.expasy.org/cellosaurus/CVCL_0058
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Anecdotal: The 'S' series of HeLa clones was named after Dr. Florence Sabin., Virology: Has at least 4 five HPV18 integration sites in the genome (PubMed=26550473)., Population: African American., Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982)., Part of: ENCODE project common cell types; tier 2.
Proper citation: NCBI_Iran Cat# C572, RRID:CVCL_0058 Copy
Contaminated Discontinued
https://web.expasy.org/cellosaurus/CVCL_1906
Organism: Homo sapiens (Human)
Disease: Human papillomavirus-related endocervical adenocarcinoma
Category: Cancer cell line
Comments: Virology: Not susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19) (PubMed=33389257)., Population: African American., Part of: KuDOS 95 cell line panel., Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=4864103; PubMed=5641128; PubMed=566722; PubMed=1246601; PubMed=20143388). Originally thought to originate from a 56 year old male patient with a laryngeal carcinoma..
Proper citation: NCBI_Iran Cat# C144, RRID:CVCL_1906 Copy
https://web.expasy.org/cellosaurus/CVCL_0327
Organism: Mus musculus (Mouse)
Disease: Hepatocellular carcinoma of the mouse
Category: Cancer cell line
Comments: Characteristics: Secretes several liver products including albumin, alpha-fetoprotein, alpha 1-antitrypin and amylase (ECACC=92110305).
Proper citation: NCBI_Iran Cat# C517, RRID:CVCL_0327 Copy
https://web.expasy.org/cellosaurus/CVCL_D293
Organism: Mus musculus (Mouse)
Disease:
Category: Hybridoma
Comments: Part of: Tumor Immunology Bank (TIB) collection from Salk (transferred to ATCC in 1981).
Proper citation: NCBI_Iran Cat# H163, RRID:CVCL_D293 Copy
https://web.expasy.org/cellosaurus/CVCL_0363
Organism: Homo sapiens (Human)
Disease: Gestational choriocarcinoma
Category: Cancer cell line
Comments: Caution: A TP53 mutation is indicated as being at p.Gln167His (c.501G>T) in PubMed=7819056 but has not been confirmed by CCLE and Cosmic-CLP., Karyotypic information: Near tetraploid karyotype (PubMed=33096371)., Characteristics: Established by serial cloning into hamster cheek pouches., Population: Caucasian., Part of: COSMIC cell lines project., Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Proper citation: NCBI_Iran Cat# C544, RRID:CVCL_0363 Copy
Discontinued
https://web.expasy.org/cellosaurus/CVCL_0059
Organism: Chlorocebus sabaeus (Green monkey)
Disease:
Category: Spontaneously immortalized cell line
Comments: Anecdotal: Verda reno means green kidney in Esperanto and Vero means truth also in Esperanto., Virology: Susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19). But Vero C1008 (often known as Vero E6) (Cellosaurus=CVCL_0574) seems to be more appropriate for amplification and quantification (PubMed=32511316; PubMed=33389257)., Virology: Susceptible to infection by SARS coronavirus (SARS-CoV). Produces a lytic infection (PubMed=15731278; PubMed=16494729)., Biotechnology: Used for the production of the Sinovax SARS-CoV-2 (COVID-19) vaccine (Trade name: CoronaVac; also known as PiCoVacc) (DrugBank=DB15806). The cell line is used to produces the inactivated SARS-CoV-2 virus strain CN02 (PubMed=32376603)., Biotechnology: Used for the production of the Bharat Biotech SARS-CoV-2 (COVID-19) vaccine (Trade name: Covaxin; also known as BBV152) (DrugBank=DB15847). The cell line is used to produces a inactivated SARS-CoV-2 virus strain., Biotechnology: Used for the production of the tetravalent dengue vaccine (Trade Name: Dengvaxia)., Biotechnology: Used for the production of the live smallpox (vaccinia) vaccine (Trade name: ACAM2000)., Biotechnology: Used for the production of the live oral rotavirus vaccine (Trade Name: Rotarix)., Biotechnology: Used for the production of the Chromatographically Purified Rabies Vaccine (CPRV)., Biotechnology: Used for the production of the Purified Vero-cell Rabies Vaccine (PVRV) (Trade name: VERORAB)., Biotechnology: Used for the production of the inactivated poliovirus vaccine (Trade name: Imovax Polio)., Biotechnology: Used for the production of the Japanese encephalitis virus (JEV) vaccine (Trade name: IXIARO/JESPECT)., Part of: Naval Biosciences Laboratory (NBL) collection (transferred to ATCC in 1982)., Group: Vaccine production cell line., Group: Non-human primate cell line.
Proper citation: NCBI_Iran Cat# C101, RRID:CVCL_0059 Copy
https://web.expasy.org/cellosaurus/CVCL_2199
Organism: Mus musculus (Mouse)
Disease: Mouse multiple myeloma
Category: Cancer cell line
Comments: Group: Hybridoma fusion partner cell line.
Proper citation: NCBI_Iran Cat# C129, RRID:CVCL_2199 Copy
https://web.expasy.org/cellosaurus/CVCL_Y438
Organism: Homo sapiens (Human)
Disease: Chronic lymphocytic leukemia
Category: Transformed cell line
Comments:
Proper citation: NCBI_Iran Cat# C547, RRID:CVCL_Y438 Copy
https://web.expasy.org/cellosaurus/CVCL_9V71
Organism: Homo sapiens (Human)
Disease: Waldenstrom macroglobulinemia
Category: Transformed cell line
Comments:
Proper citation: NCBI_Iran Cat# C215, RRID:CVCL_9V71 Copy
https://web.expasy.org/cellosaurus/CVCL_2783
Organism: Rattus norvegicus (Rat)
Disease:
Category: Hybrid cell line
Comments: Group: Hybridoma fusion partner cell line.
Proper citation: NCBI_Iran Cat# C133, RRID:CVCL_2783 Copy
https://web.expasy.org/cellosaurus/CVCL_9V35
Organism: Ovis aries (Sheep)
Disease:
Category: Finite cell line
Comments:
Proper citation: NCBI_Iran Cat# C471, RRID:CVCL_9V35 Copy
https://web.expasy.org/cellosaurus/CVCL_9V89
Organism: Ovis aries (Sheep)
Disease:
Category: Finite cell line
Comments:
Proper citation: NCBI_Iran Cat# C460, RRID:CVCL_9V89 Copy
https://web.expasy.org/cellosaurus/CVCL_9V88
Organism: Ovis aries (Sheep)
Disease:
Category: Finite cell line
Comments:
Proper citation: NCBI_Iran Cat# C464, RRID:CVCL_9V88 Copy
https://web.expasy.org/cellosaurus/CVCL_9V90
Organism: Ovis aries (Sheep)
Disease:
Category: Finite cell line
Comments:
Proper citation: NCBI_Iran Cat# C462, RRID:CVCL_9V90 Copy
https://web.expasy.org/cellosaurus/CVCL_3884
Organism: Homo sapiens (Human)
Disease: Colon adenocarcinoma
Category: Cancer cell line
Comments: From: Scott and White Clinic; Temple; USA.
Proper citation: NCBI_Iran Cat# C146, RRID:CVCL_3884 Copy
https://web.expasy.org/cellosaurus/CVCL_9V21
Organism: Homo sapiens (Human)
Disease:
Category: Hybrid cell line
Comments: Group: Hybridoma fusion partner cell line.
Proper citation: NCBI_Iran Cat# C490, RRID:CVCL_9V21 Copy
https://web.expasy.org/cellosaurus/CVCL_4326
Organism: Mus musculus (Mouse)
Disease:
Category: Spontaneously immortalized cell line
Comments:
Proper citation: NCBI_Iran Cat# C514, RRID:CVCL_4326 Copy
https://web.expasy.org/cellosaurus/CVCL_4327
Organism: Mus musculus (Mouse)
Disease:
Category: Spontaneously immortalized cell line
Comments:
Proper citation: NCBI_Iran Cat# C513, RRID:CVCL_4327 Copy
https://web.expasy.org/cellosaurus/CVCL_3420
Organism: Mus musculus (Mouse)
Disease:
Category: Spontaneously immortalized cell line
Comments:
Proper citation: NCBI_Iran Cat# C537, RRID:CVCL_3420 Copy
Misidentified
https://web.expasy.org/cellosaurus/CVCL_L803
Organism: Mus musculus (Mouse)
Disease:
Category: Undefined cell line type
Comments: Problematic cell line: Misidentified. Originally thought to be of human origin but found to be from mouse (PubMed=12592342; PubMed=20143388)..
Proper citation: NCBI_Iran Cat# C642, RRID:CVCL_L803 Copy
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