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Organism Name
unc-26(pek288[R216Q]) IV.
RRID:WB-STRAIN:WBStrain00054666 RRID Copied  
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RRID:WB-STRAIN:WBStrain00054666
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Organism Information

URL: http://www.wormbase.org/db/get?name=WBStrain00054666

Proper Citation: RRID:WB-STRAIN:WBStrain00054666

Description: Caenorhabditis elegans with name unc-26(pek288[R216Q]) IV. from WB.

Species: Caenorhabditis elegans

Synonyms: unc-26(pek288[R216Q]) IV.

Notes: Made_by: Sisi Yang|"unc-26(pek288) is a CRISPR-engineered R216Q substitution in unc-26/synaptojanin 1 associated with early-onset Parkinsonism (EOP) (Quadri et al., 2013; Krebs et al., 2013). This allele shows abnormal focal accumulation of ATG-9 in presynaptic nerve terminals, defects in activity-induced synaptic autophagy, and defects in sustained neurotransmission and locomotory behaviors in aging animals. Reference: Yang S, et al. Neuron. 2022 Mar 2;110(5):824-840.e10. PMID: 35065714"

Affected Gene: WBGene00006763(unc-26)

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Ratings and Alerts

No rating or validation information has been found for unc-26(pek288[R216Q]) IV..

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Data and Source Information

Source: Integrated Animals

Source Database: WormBase (WB)