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Proper Citation: RRID:MGI:5767567
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: increased plasmacytoid dendritic cell number, increased effector memory CD4-positive, alpha-beta T cell number, increased CD4-positive, alpha beta T cell number, decreased Ly6C-positive immature NK cell number, increased Ly6C-positive NK T cell number, increased gamma-delta T cell number, increased Ly6C low monocyte number, preweaning lethality, incomplete penetrance, decreased dendritic cell number, decreased memory-marker CD4-positive NK T cell number, increased effector memory CD8-positive, alpha-beta T cell number, decreased marginal zone B cell number, increased monocyte cell number, increased KLRG1-positive CD4-positive, CD25-positive, alpha-beta regulatory T cell number, increased KLRG1-positive NK cell number, decreased immature NK cell number, increased mature NK cell number, decreased CD8-positive, alpha-beta T cell number, decreased memory-marker gamma-delta T cell number
Affected Gene: Arhgef1
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Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI
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