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Proper Citation: RRID:MGI:3722645
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: abnormal small intestine goblet cell morphology, decreased thymocyte number, macrocytosis, increased double-negative T cell number, increased NK cell number, abnormal intestinal mucosa morphology, abnormal intestinal epithelium morphology, abnormal reticulocyte morphology, abnormal vocalization, decreased small intestinal villus size, abnormal definitive hematopoiesis, abnormal granulocyte morphology, increased number of Howell-Jolly bodies, hyperresponsive, abnormal crypts of Lieberkuhn morphology, abnormal small intestinal villus morphology, anemia, decreased body size, postnatal lethality, incomplete penetrance, thymus hypoplasia, premature death, decreased double-positive T cell number, reduced fertility, decreased fetal size, short snout, spontaneous skin ulceration, abnormal colon goblet cell morphology, broad head, decreased hematocrit, decreased granulocyte number, abnormal small intestine morphology, hemorrhage
Affected Gene: E2f4
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Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI
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