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URL: https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=2311071
Proper Citation: RRID:RGD_2311071
Description: Rattus norvegicus with name ZDF-Leprfa/fa/Crl from RGD.
Species: Rattus norvegicus
Notes: A mutation occurred in a colony of outbred Zucker rats in the laboratory of Dr. Walter Shaw at Eli Lilly Research Laboratories in Indianapolis, IN in 1974???75. Part of this colony containing the mutation was moved to Indiana University Medical School (IUMS), to the laboratory of Dr. Julia Clark in 1977. Several groups of animals with diabetic lineage were identified and rederived in 1981. Inbreeding of selected pairs from this rederivation was done in the laboratory of Dr. Richard Peterson at IUMS. An inbred line of ZDF rat was established in 1985. To Genetic Models, Inc. in 1991. To Charles River in 2001. Control models for the ZDF Rat (Obese fa/fa) are the ZDF Rat (Lean fa/+) or ZDF Rat (Lean +/?). Charles River Laboratories
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Source: Integrated Animals
Source Database: Rat Genome Database (RGD)