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URL: https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13825199
Proper Citation: RRID:RGD_13825199
Description: Rattus norvegicus with name WI-Mc4rm1Hubr from RGD.
Species: Rattus norvegicus
Notes: The Mc4r mutant rat line was generated by target-selected ENU-driven mutagenesis, and high-throughput resequencing of genomic target sequences in progeny from mutagenized rats (Wistar/Crl background) revealed an ENU-induced premature stop codon in helix 8 (K314X) of Mc4r. The heterozygous mutant rat was backcrossed to wild-type Wistar background for six generations to eliminate confounding effects from background mutations induced by ENU.
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Source: Integrated Animals
Source Database: Rat Genome Database (RGD)
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