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URL: https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=13792682
Proper Citation: RRID:RGD_13792682
Description: Rattus norvegicus with name SD-Abcc6em2Qlju+/- from RGD.
Species: Rattus norvegicus
Notes: This strain was produced by injecting ZFNs into SD embryos. ZFNs were designed to target exon 1 of rat Abcc6 gene at the binding site/cutting site 5-CACGCCTGGAGAGTCCTGcgcaggCCTGAGGGTGAGTCC-3 (c.24-c.62). The resulting mutation is a 23 bp-deletion (TGCGCAGGCCTGAGGGTGAGTCC) from the first coding exon of the rat Abcc6 gene. The mutation is predicted to cause out of frame translation and a premature stop codon. No protein in the homozygous mutant was detected by immunostaining.
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Source: Integrated Animals
Source Database: Rat Genome Database (RGD)