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Proper Citation: RRID:MGI:5517355
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: increased T cell proliferation, abnormal T cell physiology, abnormal B cell differentiation, abnormal thymus morphology, abnormal B cell physiology, thymus hyperplasia, increased IgG1 level, abnormal T cell morphology, increased B cell number, enlarged spleen, decreased follicular B cell number, decreased mature B cell number, increased B cell proliferation, increased CD4-positive, alpha-beta memory T cell number, abnormal B cell number, abnormal T cell number, decreased B cell apoptosis, autoimmune response, abnormal B cell morphology, spleen hyperplasia, increased anti-double stranded DNA antibody level, increased double-positive T cell number, increased germinal center B cell number, increased interleukin-2 secretion, increased regulatory T cell number, increased transitional stage T1 B cell number, increased spleen germinal center size
Affected Gene: Ptpn22
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No rating or validation information has been found for Ptpn22tm1.1Draw/Ptpn22+.
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Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI
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