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Proper Citation: RRID:MGI:4437914
Description: Allele Detail: Transgenic, Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Transgenic, Targeted This is a legacy resource.
Phenotype: decreased interferon-gamma secretion, alopecia, decreased CD4-positive, alpha beta T cell number, increased double-positive T cell number, decreased T cell number, decreased CD8-positive, alpha-beta T cell number, abnormal CD4-positive T cell differentiation, abnormal CD8-positive, alpha-beta T cell differentiation, decreased T cell proliferation, abnormal T cell activation, rectal prolapse, decreased single-positive T cell number, dermatitis, decreased interleukin-2 secretion, decreased body weight, increased T cell apoptosis, abnormal regulatory T cell physiology
Affected Gene: Plcg1, Gt(ROSA)26Sor
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No rating or validation information has been found for Tg(Cd4-cre)1Cwi; Plcg1tm1Gcrp/Plcg1tm1Rwen; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+.
No alerts have been found for Tg(Cd4-cre)1Cwi; Plcg1tm1Gcrp/Plcg1tm1Rwen; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+.
Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI
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