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Proper Citation: RRID:MGI:3768245
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: small Peyer's patches, decreased IgM level, large intestinal inflammation, peritoneal inflammation, increased susceptibility to bacterial infection induced morbidity/mortality, abnormal humoral immune response, decreased myeloid dendritic cell number, increased susceptibility to bacterial infection, cecum inflammation, decreased B cell proliferation, abnormal class switch recombination, premature death, decreased immunoglobulin level, abnormal Peyer's patch T cell area morphology, abnormal Peyer's patch follicle morphology, decreased Peyer's patch number, abnormal Peyer's patch germinal center morphology, abnormal colon morphology, diarrhea, decreased interleukin-6 secretion, decreased IgA level, decreased IgE level, decreased IgG1 level, decreased susceptibility to viral infection induced morbidity/mortality, decreased B cell proliferation, increased susceptibility to bacterial infection
Affected Gene: Nfkb1
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Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI
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