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Proper Citation: RRID:MGI:3041700
Description: Allele Detail: Targeted This is a legacy resource.
Species: Mus musculus
Notes: Allele Detail: Targeted This is a legacy resource.
Phenotype: abnormal macula densa morphology, dehydration, increased circulating potassium level, abnormal ion homeostasis, renal/urinary system phenotype, abnormal renal sodium ion transport, abnormal juxtaglomerular apparatus morphology, abnormal juxtaglomerular cell morphology, abnormal extraglomerular mesangial cell morphology, postnatal lethality, complete penetrance, abnormal renal sodium reabsorbtion, increased circulating renin level, weight loss, increased hematocrit, increased renin activity, decreased circulating sodium level, hypovolemia, increased urine sodium level, abnormal renal glomerulus morphology, increased circulating aldosterone level
Affected Gene: Nr3c2
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Source: Integrated Animals
Source Database: MGI, Mouse Genome Informatics MGI