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Organism Name
B6;129S7-Prnptm1Cwe Tg(Prnp)a19Cwe/CweCnrm
RRID:IMSR_EM:00180 RRID Copied  
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RRID:IMSR_EM:00180
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Organism Information

URL: https://www.infrafrontier.eu/emma/strain-details/?q=180

Proper Citation: RRID:IMSR_EM:00180

Description: Mus musculus with name B6;129S7-Prnptm1Cwe Tg(Prnp)a19Cwe/CweCnrm from IMSR.

Species: Mus musculus

Synonyms: PrPC-KO. Tga19. B6;129S7 Prnp-Tg(Prnp)a19Cwe/Cwe. Tga19. STOCK Prnp Tg(Prnp)19Cwe. B6;129S7-Prnp Tg(Prnp)a19Cwe/CweIbcm

Notes: gene symbol note: transgene insertion a19; Charles Weissmann|prion protein; mutant strain: Tg(Prnp)a19Cwe|Prnp

Affected Gene: transgene insertion a19; Charles Weissmann|prion protein

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Ratings and Alerts

No rating or validation information has been found for B6;129S7-Prnptm1Cwe Tg(Prnp)a19Cwe/CweCnrm.

Issue
Warning. Researchers have noted that this genotype does not sufficiently model human Creutzfeldt-Jakob disease.

Issue
Warning. Researchers have noted that this genotype does not sufficiently model human Gerstmann-Straussler-Scheinker syndrome.

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Data and Source Information

Source: Integrated Animals

Source Database: European Mouse Mutant Archive