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URL: https://github.com/virajbdeshpande/AmpliconArchitect
Proper Citation: AmpliconArchitect (RRID:SCR_023150)
Description: Software package designed to call circular DNA from short read WGS data.Used to identify one or more connected genomic regions which have simultaneous copy number amplification and elucidates architecture of amplicon.Used to reconstruct structure of focally amplified regions using whole genome sequencing and validate it extensively on multiple simulated and real datasets, across wide range of coverage and copy numbers.
Resource Type: software resource, software toolkit
Defining Citation: DOI:10.1038/s41467-018-08200-y
Keywords: call circular DNA, short read WGS data, connected genomic regions identification, simultaneous copy number amplification, amplicon
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