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URL: http://pga.gs.washington.edu
Proper Citation: SeattleSNPs - Variation Discovery Resource (RRID:SCR_001859)
Description: The SeattleSNPs PGA is focused on identifying, genotyping, and modeling the associations between single nucleotide polymorphisms (SNPs) in candidate genes and pathways that underlie inflammatory responses in humans. SeattleSNPs is focused on variation analysis in genes related to the inflammatory response. These gene targets are found in specific pathways and from interacting molecules contributing to this response. Available Resources: - Baseline assembled and complete genomic sequence and chromosomal location for candidate gene targets - Mapping of exon and repeat structure for candidate genes - Amplification primers and conditions - SNPs mapped by location in gene structure - SNPs with immediate surrounding sequence for genotype assay design - Genotypes and relative allele frequencies of the SNPs - Special features of SNPs - location (5', coding, etc.), amino acid substitutions, recurrent variation - Manuals on all protocols, data analysis procedures, and use of software tools - Workshop on genetic variation analysis and a gene submission program for variation analysis Sponsors: SeattleSNPs is funded as part of the National Heart Lung and Blood Institute's (NHLBI) Programs for Genomic Applications (PGA).
Synonyms: SeattleSNPs
Resource Type: portal, software resource, training material, data or information resource, narrative resource, topical portal
Keywords: exon, gene, gene target, allele, amino acid, amplification, assay, chromosomal, genomic sequence, genotyping, humans, inflammatory response, molecule, pathway, primer, recurrent varation, repeat structure, singe nucleotide polymorphism (snp), substitution, variation analysis
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